Relevant organisms Flashcards
For an antibiotic to work it must
Enter the bacterial cell
Reach its site of action
Bind to a target that is involved in an essential bacterial function
Significantly impair that function
Gram Postive
___ peptidoglycan layer
thick
Gram Negative
___ peptidoglycan layer
Thin
Outer membrane of gram negative bacteria contains
lipopolysaccharides and porins
porins are
small hydrophilic channels that permit diffusion of nutrients and small molecules
Periplasmic space
Located between cytoplasmic membrane and outer membrane of Gram negative bacteria
Location of beta-lactamases in Gram-negative bacteria
Gram Positive Aerobic Organisms:
Cocci Clusters
Coagulase positive
Staphylococcus aureus
Gram Positive Aerobic Organisms:
Cocci Clusters
Coagulase negative
other Staphylococcus species: epidermidis, hominis, haemolyticus, capitus, saprophyticus
Gram Positive Aerobic Organisms:
Pairs and Chains
Streptococcus spp.
Enterococcus spp.
Gram Positive Aerobic Organisms:
Rods
Listeria
Nocardia
Gram Postive Anaerobic
Cocci
peptostreptococcus
Gram Postive Anaerobic:
Rods
Clostridium spp. (spore-forming)
Propionibacterium
Actinomyces
Gram Negative Aerobic
Bacilli (Rods)
Lactose-fermenting
Enterobacteriaceae family (gut bacteria)
Escherichia coli Klebsiella pneumoniae Enterobacter spp. Proteus mirabilis Salmonella spp.
Gram Negative Aerobic
Bacilli (Rods)
Non-Lactose-fermenting
Pseudomonas aeruginosa
Acinetobacter baumannii
Stenotrophomonas maltophila
Gram Negative Aerobic:
Cocci
Neisseria meningitidis
Neisseria gonorrhoeae
Moraxella catarrhalis