Relapse Risks

Question 1

What is the risk of relapse after a first depressive episode?
After a second MDE?
After a third MDE?

Answer 1

1st - 50%
2nd - 80%
3rd - >90%

Question 2

What is the risk of subsequent mood episodes after a first manic episode?

Answer 2

> 90%

Question 3

What is the risk of relapse after a first brief psychotic episode?

Answer 3

80% (4 in 5 will have a recurrence within 5 years)

Question 4

How many people with schizophreniform disorder will go on to develop schizophrenia/schizoaffective d/o within 2 years?

Answer 4

~50%

Question 5

How many people with MCI will go on the develop Major Neurocognitive Disorder?

Answer 5

Cumulative: 1/3, with a conversion rate of about ~10% per year and most converting within 2-3 years