reintroduction to microbiologie Flashcards

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1
Q

microorganisms

A

Eukaryotes

  • protozoa
  • fungi

prokaryotes - bacteria
viruses
prions

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2
Q

protozoa

A

unicellular eukaryotes
often affect immunocrompomised
many free living

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3
Q

funig

A
eukaryotic
different froms
external rigid wall of chitin
filamentous or yeast forms
dimorphic if display different forms
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4
Q

bacteria cellular forms

A
cocci
diplococci
tetrags
sarcina
streptococci
staphylococci
bacilli
extended irregular rods
kidney bean
corkscrew
helical
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5
Q

gram +/-

A
Gram +
-	purple
-	retain gram stain
-	1 membrane
-	peptidoglycan outer layer i.e. cell wall
Gram – 
-	pink
-	2 membranes
-	inner and outer membrane
-	periplasmic space between
-	LPS on the outside
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6
Q

peptidoglucan

A
  • polymer of N acetyl muramic acid and N acetyl glucosamine

- crosslinked via amino acid pentapeptides and anchored to cell wall

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7
Q

pili and fibriae

A
  • proteinaceous filamentous structures

- often used for attachment to host cells or surfaces

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8
Q

pathogen

A

disease causing bacteria

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9
Q

opportunistic

A

commensals that sometime cause disease

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10
Q

e coli

A

gram - rod

commensal

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11
Q

bacteriodes

A

gram - anaerobic bacilli

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12
Q

clostirdal

A

gram + anaeboic spore forming bacilli

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13
Q

mycobacteria

A

thick cell wall of mycolic acid (waxy nature)

ziehl Nielsen stain red
cannot be stained with gram +/- stain

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14
Q

chlamydia

A

obligaet

gram - cell wall

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15
Q

viruses

A

obligate intracellular paracites

viral genome uses host to encode viral protiesn

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16
Q

basic viral structure

A

nucleic acid encapsulated by proteinaceous capsid
varying shape and symmetry
some have lipid coat

17
Q

lytic life cycle

A
  • virus attaches to cell
  • endocytosis
  • uncoats
  • replicates genome via host mechanisms
  • threshold reached and bursts
18
Q

viral latency

A

Infection does not result in lytic life cycle

1) incorporation into genome – retrovirus
2) latent infection of host cell away from site of infection eg herpes

19
Q

prions

A

heat resistant
Normal PrPc converted to rogue
aggregate into long fibres and amyloid plaques