REI

Question 1

Most common uterine change with Tamoxifen

Answer 1

Uterine polyps (8-36%) Endometrial hyperplasia (1-20%)

Question 2

What fold increase of uterine cancer with Tamoxifen

Answer 2

1.3-7.5x

Question 3

How to diagnose APLS

Answer 3

1 clinical + 1 lab (twice)

Question 4

Diagnosis of premature ovarian failure

Answer 4

age <40

3m amenorrhea

FSH >40 on two measures weeks apart

Question 5

Causes of premature ovarian failure

Answer 5

Fragile X permutations (16-25% of women with this get POI)

XO

17-a-hydroxylase deficiency

Galactosemia

aromatase deficiency

chemo

radiation

viral infection

autoimmune

unknown

Question 6

Medication to prevent OHSS

Answer 6

Cabergoline

Question 7

What BMI to offer bariatric surgery?

Answer 7

>40, or 35 with RF

Question 8

Genetic risk for ICSI

Answer 8

Imprinting disorders - Beckwith Wideman, Angelmans

Question 9

What percentage to OCPs reduce the risk of ovarian cancer

Answer 9

50%! (even for BRCA+ patients!)

Effect lasts 30 years after discontinuation

Question 10

What stages of endometriosis does removal of implants improve fertility

Answer 10

I and II

No evidence for or against III or IV

Question 11

Above how many cm does removal of an endometrioma improve fertility

Answer 11

>4cm

Question 12

First line/most cost effective intervention for unexplained infertility

Answer 12

Clomid WITH IUI

(clomid alone or IUI alone does not increase rate of live birth)