Regulation of GI System Flashcards

1
Q

What are the two main components of neural regulation in digestion?

A
  1. Enteric nervous system (ENS)
  2. Autonomic nervous system (ANS)
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2
Q

How does the parasympathetic nervous system affect digestion?

A

It stimulates digestion, increasing motility and secretions.

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3
Q

How does the sympathetic nervous system affect digestion?

A

It inhibits digestion, reducing motility and blood flow.

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4
Q

What are the three phases of regulation?

A

Cephalic, gastric and intestinal

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5
Q

What triggers the cephalic phase of digestion?

A

The sight, smell, taste, or thought of food.

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6
Q

What happens during the cephalic phase?

A

The CNS stimulates saliva, gastric acid, and digestive enzyme secretion

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7
Q

What stimulates the gastric phase?

A

Stomach distension and the presence of peptides in the stomach.

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8
Q

What is the intestinal phase triggered by?

A

The presence of chyme in the duodenum.

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9
Q

Which hormone increases appetite and where is it secreted?

A

Ghrelin, secreted by the stomach when it is empty.

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10
Q

Which hormone signals satiety and where is it secreted?

A

Leptin, secreted by adipose tissue.

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11
Q

What role does insulin play in appetite regulation?

A

Promotes satiety by acting on the hypothalamus.

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12
Q

What hormones are released during digestion to suppress appetite?

A

Peptide YY (PYY) and Cholecystokinin (CCK)

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13
Q

What is peristalsis?

A

Wave-like contractions that propel food through the digestive tract.

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14
Q

What is segmentation?

A

Alternating contractions that mix chyme in the small intestine.

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15
Q

What are short reflexes in the ENS and give an example.

A

Reflexes confined entirely to the ENS, independent of the CNS. For example, the local stretch of the intestinal wall triggers nearby peristalsis and secretion.

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16
Q

What are long reflexes in the ENS?

A

Reflexes that involve communication between the ENS and the CNS via the autonomic nervous system.

17
Q

What neurotransmitter makes the gut muscles contract?

A

Acetylcholine (ACh)

18
Q

Where is the ENS located?

A

Entirely within the wall of the GI tract.

19
Q

Outline the roles of CCK, gastrin, VIP and secretin.

A
  1. Stimulates the pancreas to secrete digestive enzymes.
  2. Stimulates the stomach to secrete HCl.
  3. Inhibits pancreatic secretions.
  4. Stimulates the pancreas to secrete bicarbonate.