Regional Flashcards
what anesthetic agents can cause neuroapoptosis?
- GABAA agonists (propofol, benzos, volatile agents)
- NMDA antagonists (ketamine, N2O
what age kids are at risk of neuroapoptosis?
what increases the risk?
- kids < 3 yrs (occurs in utero during 3rd trimester too)
- increased risk with anesthesia time > 3 hrs and repeated exposure
why is use of neuraxial and regional techniques growing?
to avoid GA
T/F: regional techniques are safe and effective for intra-op and post-op analgesia in infants, children, but not in pre-term neonates
false - safe for infants, children, and neonates
advantages for using regional/spinals in peds
- opioid related adverse effects avoided
- promotes spontaneous ventilation and earlier extubation
- reduces risk of post-op apnea and respiratory dysfunction in high-risk infants
- airway instrumentation can be avoided
- enhances hemodynamic stability
advantage of continuous epidural analgesia in peds
- decreases time to extubation
- promotes return of bowel function
- decreases metabolic stress response
- may decrease postoperative sedation needs
- promotes shorter ICU length of stay
little fact: when combined with GA, regionals decrease intra-op volatiles, opioids and neuromuscular blocking agents
(reduces risk of negative cognitive outcomes)
yay
indications for spinals (5)
- lower abdominal procedures (urologic and hernias)
- lower extremity orthopedics
- omphalocele
- exploratory laparotomy
- myelomeningocele
T/F: there are frequent complications with spinal use in peds, mainly being permanent neurologic injury or death
false
“Complications infrequent; no reports of permanent neurological injury or death in children”
what can be added to a spinal to double the duration?
clonidine
complex procedures often benefit from a spinal combined with what other technique?
caudal catheter
agents commonly used for sedation with spinals?
precedex - infusion
fentanyl, midazolam - boluses
difference in conus medullaris in peds vs adults?
when is it the same as adults?
conus medullaris more caudal in neonates and infants (L3)
reaches adult level at 1 y/o
level of lumbar puncture in peds vs adults?
why?
at L4-L5 or L5-S1 to avoid spinal cord trauma
what approach to a spinal is preferred in peds?
midline
difference in sacrum in peds vs adults
- sacrum more narrow and flat
- access to subarachnoid space from caudal canal more direct (dural puncture more likely)
differnce in ligamentum flavum in peds vs adults?
consideration?
less dense in peds
harder to feel loss of resistance
duration of spinal in peds vs adults?
why the difference?
- peds have shorter block duration
- due to faster CSF turnover rate
in a pediatric patient, how much space is between the skin and the subarachnoid space?
1.5 cm
T/F: a spinal eliminates the incidence of post-op apnea in former premies
false - decreases but does not eliminate