Regenerative Perio Flashcards

1
Q

What are examples of regenerative techniques?

A

Bone substitutes
Guided tissue regeneration
Growth factors and biologics
Grafting and combined therapies

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2
Q

What are 3 ways bone substitutes?

A

Bone forming cells = osteogeneisis
Scaffold cells = osteoconductive
Bone inducing = osteoinduction

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3
Q

Types of bone substitutes?

A
Bone autogenous
Bone allograft
Bone xenograft
Bone alloplastic material
Bioactive glass
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4
Q

What is bone autogenous graft?

A

Autograft

Bone taken from elsewhere pt body

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5
Q

What is bone allograft?

A

Use of bone tissue from donar

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6
Q

What is done xenograft?

A

Use of bone tissue from another species

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7
Q

What is alloplastic graft?

A

Hydroxyapatite

Substance found in bone

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8
Q

What is Bio-Oss?

A

Bone xenograft

Bio-Oss = bovine porous bone mineral

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9
Q

How does Bio-Oss work?

A

Causes clot stabilisation –> revasularisation and migration of osteoblast –> growth of woven bone enhance by scaffold of BioOss
Bone integration

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10
Q

How to use Bio-Glass?

A

Introduce into defect site –> react w/ body fluids

Modified surface bioglass induces tissue regeneration

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11
Q

Why is guided tissue regeneration used in perio?

A

Used to prevent epithelial migration along cement wall of pocket

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12
Q

What is GTR?

A

Placing a membrane barrier to cover bone and PDL - separates bone and PDL from gingival epithelium
Prevents epithelial migration favouring repopulation by cells PDL/bone

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13
Q

Basic technique of GTR?

A

Surgical flap
Membrane inserted
Suture into position

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14
Q

What kind of membranes are used?

A

Resorbable

Prevents second surgery which could damage newly formed tissue

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15
Q

Example of growth factor/biolpgical?

A

Enamel matrix derivatives = Emdogain

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16
Q

What is Emdogain?

A

Made from enamel matrix protein of tooth germ of swine in matrix

Applied as gel to exposed intra-bony defects

17
Q

What does Emdogain do?

A

Differentiate cells at dental follicle into cementoblast

18
Q

What scenarios can Emdogain be used in?

A

Intra-bony defects

Recession

19
Q

What is procedure for tx of recession w/ Emdogain?

A
Coronally advanced flap
Root surface conditioning
Emdogain application
Periodontal dressing
Maintenance