Refractive development and prescribing in children Flashcards

1
Q

what does prescribing =

A

management of refractive error

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2
Q

list 3 reasons why you would prescribe a refractive correction in adults

A

Manage ametropia
Symptoms

Occupational

Manage BV problems

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3
Q

list 3 reasons why you would prescribe a refractive correction in children

A

Manage ametropia
Symptoms?

Prevent amblyopia

To treat amblyopia
Manage BV problems

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4
Q

what 3 things will you consider/rule out before prescribing a refractive error for a child

A

No POH
FTND (full term normal delivery)
No FOH
BSV

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5
Q

what 4 questions do you want to ask yourself before you prescribe

A

Is refractive error within normal range for age?

Is emmetropization still taking place?
Will prescribing interfere with emmetropization?

Will level of refractive error cause amblyopia?

Will prescribing spectacles improve vision?
Will child adapt to their refractive correction?

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6
Q

what is the mean range of refractive error for a child 0-12 months of age
what type of refractive error are most of these infants found to have
how many of infants in this age group have anisometropia and of what D value

A

Large spread of refractive error
Mean cyclo refraction +2DS ± 2SD = -2 to +4 is normal

Most infants are hyperopic

Anisometropia >1.00DS = 31%

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7
Q

what is the prevalence of astigmatism that is normal for a child 0-12 months of age and what is the D value
which type of astigmatism is more common than in adults
by what age is astigmatism lost and how much of it is lost

A

Astigmatism >1.00DC = 67.8%

Significant WTR and ATR astigmatism more common than in adults

About two-thirds of astigmatism lost by 18 months

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8
Q

what happens to the spread of refractive error by the age of 6
what is the mean range of refractive error
by what age will astigmatism settle down by for a child ages 3-6 years old
which type of astigmatism is more common in later childhood

A

Very narrow spread of refractive errors
Mean +0.75DS to +1DS

Astigmatism may not stabilise till age 5

WTR astigmatism more common in later childhood than ATR

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9
Q

what is anisometropia
which age group of children is it more common in
what is the prevalence of anisometropia is this age group and of what D value
what 2 things is anisometropia commonly associated with

A

Interocular difference in refractive states between R and L eyes

More common in infants 0 to 3 years

Anisometropia >1.00DS = 31%

More commonly associated with:

  • Hyperopic than myopic corrections
  • Large refractive errors > +5.00DS or > - 6.00DS
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10
Q

what did the los angeles study discover about the worldwide prevalence of ametropia in children between age 6 months - 6 years old about:
Myopia
Hyperopia
Astigmatism

A

Myopia:

  • values of anything over -0.50D was considered (so not high)
  • if far less common than hyperopia
  • but is more likely in asian children than white children
  • myopia prevalence stable prevalence across age groups

Hyperopia:
- most common refractive error in both Asian and white children
but
- is more common in white children than in asian children (i.e. in east and south asian children)
- prevalence decreased after infancy and then increased again in older age groups

Astigmatism
- WTR astigmatism predominated at all ages

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11
Q

describe which types of ethnic children and environments myopia is more prevalent in and less prevalent in

A

More prevalent in:
Chinese children
Urban environments

Less prevalent in:
European children
Rural environments

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12
Q

which ethnic background had the highest prevalence of myopia living in the UK which was second and which was the lowest
what refractive error value did the account for
which age group did this account for
what was the ethnic difference largely accounted for

A
  • South asian
  • black
  • white european
  • -0.50D >
  • age 10-11 years old
  • largely accounted for by ethnic differences in axial length
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13
Q

in which age group is the prevalence of myopia higher

and therefore when will myopia in a child increase

A

higher in 12 y/o compared to 6-7 y/o

myopia will increase most likely as the child gets older

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14
Q

what is Emmetropization

A

Developmental process that co-ordinates growth of refractive component of eye

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15
Q

what is the two separate theories/processes of Emmetropization

A

Active

  • Visual experience guides refractive state towards emmetropia
  • Self-controlling – ability to recognise and correct imperfections

Passive

  • Genetic control
  • Pre-programmed
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16
Q

what are the 4 factors involved with genetics and emmetropisation

A

Twin studies
Myopia genes
Family history
Prevalence varies from country to country

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17
Q

what are the 6 factors involved with environment and emmetropisation

A
Increased near work
Parental cigarette smoking
Accommodative lag and variability
Decreased time spent outdoors
Urban environment 
Increased ambient lighting at night-time
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18
Q

between which ages does emmetropisation occur fast

and by when does it slow down for hyperopes and for myopes

A

Fast from 3 to 12 months

Age 2 years for hyperopes
Age 4 to 5 years for myopes

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19
Q

by what age is emmetropisation mostly complete

which types of children have faster changes

A

Mostly complete by 3 years of age

Faster changes in those with higher ametropia

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20
Q

how can you see whether emmetropisation has taken place in a child or if its still occurring

A

you monitor their refraction over a period of 4-6 months

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21
Q

which 3 types of patients will less likely emmetropise

A

Very high refractive error (> 5DS at 3 months)
Poor VA
ATR astigmatism

22
Q

in which types of patients is emmetropisation less likely to be transient and what do you need to consider at this point

A

Anisometropia > 3DS less likely to be transient

Consider VA – amblyopia

23
Q

what should you do when a child is going through emmetropisation to encourage the process to take place and how does this help

A

prescribe the full rx - as your giving a full stimulus

Some believe that while emmetropization is active, a partial correction should be prescribed (i.e. under-correction of the refractive error) to allow a stimulus for emmetropization…
However, evidence does not support this

24
Q

what is a risk factor of amblyopia

A

Uncorrected high refractive error during first few years of life

25
Q

what is the RCO guidelines risk factors for the development of amblyopia in children age 3+ with isometropia (hence at what rx do you need to prescribe from) in:
Myopia
Hyperopia
Astigmatism

A

Isometropia: same rx between both eyes

Myopia: -3.50D in one meridian
Hyperopia: +4.50D in one meridian
Astigmatism: 2.00D

26
Q

what is the RCO guidelines risk factors for the development of amblyopia in children age 3+ with anisometropia (hence at what rx do you need to prescribe from) in:
Myopia
Hyperopia
Astigmatism

A

Anisometropia: difference of 2.00D rx between both eyes

Myopia: -2.00D
Hyperopia: +1.50D
Astigmatism: 2.00D

27
Q

which type of uncorrected rx will it be most likely for a child age 3+ to develop amblyopia and an esotropia

A

Hyperopia > +4.50DS (in one meridian)

28
Q

when will a child be more asymptomatic about their uncorrected ametropia

A

when they’re at school

29
Q
for a child who is at school age, when/how much will you correct their:
Myopia
Hyperopia
Astigmatism
Anisometropia
A

Myopia
- Full correction of myopia
(No evidence that under- or partial correction reduces myopia progression)

Hyperopia
- Uncorrected hyperopia >+1.50DS can impact VA
Little solid evidence of benefit of correcting small refractive errors (up to +1.50DS, or astigmatism up to 1DC)

Astigmatism
- Correct astigmatism >2DC

Anisometropia
- Correct anisometropia of > +1.50DS hyperopia, > -2.00DS myopia

30
Q

what will you do for a
18 months old child
V: R 6/12 L 6/12

Cyclo ret:
R +4.50DS
L +4.50DS

A

Not prescribe

will monitor them in 1 year

31
Q

what will you do for a
3 years old child
V: R 6/18 L 6/18

Cyclo ret:
R +6.00DS
L +6.00DS

A

Prescribe full rx
full time wear - this rx is amblyogenic
follow up next sight test in 6 weeks

32
Q

what will you do for a
4 years old child
V: R 0.28 logMAR L 0.22 logMAR

Cyclo ret:
R: +0.50/-1.50x180 VA 0.22
L: +0.50/-0.50x180 VA 0.20

A

Not prescribe
will monitor them in 1 year
this rx will not be likely to cause amblyopia
child will also not be symptomatic

33
Q

what will you do for a
6 years old child
V: R 0.28 logMAR L 0.12 logMAR

Cyclo ret:
R: -0.50/-1.50x180 VA 0.00
L:-0.50/-0.50x180 VA 0.00

A

Prescribe full rx
full time wear
this child will be symptomatic and there shows to be an improvement in va’s with new rx
monitor to look for progression and if it quickly progresses then you need to monitor them every 6 months

34
Q

what do you need to advise to the parent when prescribing glasses to an asymptomatic child

A

that the rx is important to use as its there to prevent amblyopia

35
Q

what are the 8 myths regarding young children and prescriptions

A

do not need spectacles
will not wear spectacles
will benefit from small hyperopic prescriptions
will not tolerate full astigmatic corrections
will not tolerate full hyperopic prescriptions
will not tolerate a full anisometropic prescription
should be given partial prescriptions
do not require bifocals, they are for old people!

36
Q

list 6 facts about the risk factors of myopia

A

Environmental factors play a crucial role in myopia development

Effect of gene-environment interaction on the aetiology of myopia is still controversial with inconsistent findings in different studies

A relatively hyperopic periphery can stimulate compensating eye growth in the centre

High levels of near work but low levels of outdoor activity had the least hyperopic mean refraction

Low levels of near work but high levels of outdoor activity had the most hyperopic mean refraction

Low outdoor time AND high near work were two to three times more likely to be myopic compared to those performing low near work and high outdoor activities

37
Q

what is the prevalence of pathological myopia

what 2 pathological eye conditions can it cause

A

1 to 3% of population

Chorio-retinal degeneration
POAG

38
Q

what are the 4 signs of Chorio-retinal degeneration (a pathological eye condition of myopia)

A

Lacquer cracks
Fuch’s spots
Retinal tears and breaks
Retinal detachment

39
Q

what consequence/problems can pathological myopia have on
a normal class child
on children in the third world
and what restriction will the child have in the future

A

Continued costs of correction

Limited access to corrective appliances in third world

Restrictions on career choices
Pilot, fire-fighter, police

40
Q

name 2 systemic conditions associated with myopia

A

Marfan’s syndrome

Stickler Syndrome

41
Q

what is Marfan’s syndrome and what are the 6 signs

A

Connective tissue disorder (associated with myopia)

Long arms, legs and fingers; tall thin body type
Severe myopia
Dislocated lens
Detached retina
Early glaucoma
Early cataracts
42
Q

what is Stickler Syndrome and what are the 4 signs

A

Genetic connective tissue disorder (associated with myopia)

Paravascular vitreo-retinal degenerations
Dragging of retinal vessels at disc
Condensations of vitreous gel
Multiple posterior vitreo-retinal adhesions

43
Q

what is the outcome of pre term babies without retinopathy or prematurity ROP
what is the outcome pre term babies with retinopathy or prematurity ROP

A

Infants without ROP are myopic at birth but tend towards emmetropia as they approach full term

Infants with ROP have high rates in the development of myopia
Treatment does not seem to affect refractive error

44
Q

in extremely premature babies, what is their:
Mean spherical equivalent
Astigmatism value and prevalence
Anisometripia value and prevalence

A

MSE: -4.86D but + 2.4D at term
Astigmatism: 1.00D – 67.8%
Anisometropi: 1.00D – 31%

so higher rate or astigmatism and anisometropia and higher rate of myopia in premature babies

45
Q

list 7 treatments/managements that are thought to prevent myopia

A

Atropine
to paralyse accommodation

Bifocals and multifocals
to reduce accommodation at near

Contact lenses
To flatten cornea or retard axial elongation
Orthokeratology

Under-correction

Diet

Outdoor activities

Sunlight

But at present, there are no definitive answers

46
Q

what is high hyperopia not considered to be

what are the 3 ocular signs of high hyperopia

A

NO pathological hyperopia

Shallower vitreous and anterior chambers

Optic nerve head drusen

Large positive angle kappa, giving appearance of divergent strabismus (so look at ret results to see if it links)

47
Q

list 2 ocular conditions associated with hyperopia

A

Autosomal dominant nanophthalmos

Leber Amaurosis

48
Q

what is Autosomal dominant nanophthalmos and what are the 3 ocular signs

A

Uncommon developmental ocular disorder

Small eye
High incidence of CAG
Hyperopia

49
Q

what is Leber Amaurosis and what are the 2 ocular signs

A

Inherited retinal disorder

Nystagmus
Hyperopia

50
Q

name a hyperopia associated syndrome

A

Down’s Syndrome

51
Q

what do children with down’s syndrome fail to do and hence what is the outcome of their hyperopia, myopia and range of rx
what other ocular signs will they have and what is the prevalence

A
Failure to emmetroprize
Hyperopia > 3.00DS ~40%
Myopia > 0.75DS  ~11%
Range +8.00DS to -7.50DS
= has significant ametropia, so must correct it before they get amblyopia 

Astigmatism > 1.00D ~55%

Strabismus ~ 30%

Poor accommodation (these kids are mostly given bifocals)

52
Q

list 8 eye conditions linked with astigmatism

A
Previous eye surgery
Previous corneal injury
Corneal dystrophies
Congenital cataract
Optic nerve hypoplasia
Retinitis pigmentosa
Albinism
Nystagmus