Reduced Lung Volume Flashcards
How is alveolar ventilation measured?
Respiratory rate x (tidal volume - deadspace)
What is regional ventilation?
Ventilation in specific regions of the lung
What is minute ventilation?
Respiratory rate x tidal volume
What is functional residual capacity?
Resting volume of the lung at the end of tidal breaths
What is the difference between atelectasis and lung collapse?
- Atelectasis is the collapse of alveoli
- Lung collapse is the collapse of whole regions of the lung
What is FRC a balance of?
- Inward elastic recoil of the lungs
- Springing out of the ribcage
What is closing capacity?
Volume of gas in the lungs at the time when small airways in the dependent portions (lower portions) of the lungs close during maximal exhalation
Why is pleural pressure less negative at the bottom of the lungs?
Because gravity pulls down the weight of the lung, making the space bigger (i.e. less pressure)
How is closing capacity measured?
Single breath nitrogen test
What factors does closing capacity increase with?
Age, COPD, smoking (loss of elastic recoil)
What is the relationship between closing capacity and body position?
- Higher when standing upright
- Lower when supine
What occurs when CC > FRC?
Dependent airway closure occurs during tidal breathing, i.e. much more likely to get lung collapse in those airways
What is the difference between CC and equal pressure point?
- CC is a volume
- EPP is where pleural pressure & pressure within alveoli are equal causing dynamic collapse (pressure-related, nothing to do with dependence/non-dependence)
What are the causes of reduced lung volume?
- External compression of lung tissue
- Reduced chest wall compliance
- Reduced central drive
- Decreased ability of respiratory muscles to generate force
- Loss of alveolar volume
What can cause external compression of lung tissue?
- Pleural space: Pleural effusion, empyema (pus), pneumothorax
- Abdomen: ascites (fluid), pregnancy, obesity
- Rib cage: Posture, flail segment, kyphoscoliosis
What causes reduced chest wall compliance?
- Kyphoscoliosis
- Obesity
- Pregnancy
- Age