Red flags Flashcards
Red flag symptoms for abdominal pain
Gastrointestinal
* Sudden onset
* Haematemsis
* Change in bowel habit (more loose stool) for >3 weeks
* Dysphagia
* New onset dyspepsia
* Persistent unexplained vomitting
* Any abdominal distension
* Not passing flatus or absolute constipation
Urological
* Haematuria
* Testicular pain +/- swelling
* Inability to pass urine
Other
* Fever
* Presyncopal
* SOB
* Unexplained weight loss
* New rash
Red flags symptoms for amenorrhoea
- Older than 14 years and no signs of puberty
- Visual field defects or lack of sense of smell
- Virilisation
- Excessive weight loss
- Galactorrhoea
- Presence of abdominal mass
- No obvious cause
Red flag symptoms for arrhythmias
- Persistent arrhythmias, increasing in frequency
- Chest pain or dyspnoea
- Pre-syncope
- Syncope w/ or w/o palpitations
- Exertional palpiatations
- Unintentional weight loss
- FHx of sudden death
- Recreational drug use
- Alcohol misuse
Red flag symptoms for back pain
- Signs and symptoms suggestive of cauda equina or cord compression
- Immunosuppression
- Trauma
- Hx of cancer
- Nocturnal pain
- Systemic upset - unintentional w/l, night sweats, fevers
- Thoracic pain
- Abnormal gait
- History of steroid use
- Age less than 20 or >55
- History of osteoporosis
- Associated light headedness
Red flag symptoms for blurred vision
- Sudden onset
- Loss of vision
- Associated headache or weakness of arm, face or leg
- Speech disturbance
- Associated nause, vomiting or photophobia
- Any history of sudden eye pain and or redness
- Hx of trauma
- Scalp tenderness or jaw claudication
- New medications
- Polyuria or polydipsia and or unintentional w/l
- Problems w/ bright lights
- Flashers or floaters
- Recent COVID-19
Red flag symptoms for breathlessness
- Associated chest pain or palpitations
- Sudden onset with persistent symptoms
- Visible physical signs (cyanosis, unable to speak in sentences, confusion, agitation)
- Leg swelling
- Noisy breathing (stridor, wheeze, persistent cough)
- Hx of prolonged immobility, trauma or previous complications w/ breathing
- Onset of or worsening orthopnoea
- Haemoptysis
Red flag symptoms for chest pain
- Exertional
- Sudden onset
- Dyspnoea
- Haemoptysis
- Significant unintentional weight loss
- New onset dyspepsia if >55
- Hx of leg swelling, long-haul flights or any recent periods of immobility
- Cough for >3 weeks and/or fever
Red flag symptoms for constipation
- Change in bowel habit for more than 6 weeks
- Persistent rectal bleeding
- W/l, night sweats, appetite loss
- FHx of colorectal pathology
- Pain
- Vomiting
- Abdominal bloating
- New-onset confusion
- Significant weight gain
- Urinary urgency (women)
- Tenesmus (feeling of incomplete emptying)
- Inability to pass flatus
Red flag symptoms for persistent cough
- Persistent cough for >3 weeks
- Pleuritic chest pain
- Dyspnoea
- Haemoptysis
- Persistent nocturnal cough
- Wheeze
- Recurrent chest infections
- Coughing up phlegm every morning for more than 3 months of the year
- Unintentional weight loss
- History of night sweats
Red flag symptoms for diarrhoea
- Symptoms >4 weeks
- Bloody diarrhoea
- Unintentional weight loss
- Nocturnal diarrhoea
- Reduced urine output
- History of fever
- History of foreign travel
- History of eating out
- Significant abdominal pain
Red flag symptoms for diplopia
- Persistent headaches
- Changes in pupillary size
- Drooping of the eyelids
- Ocular fatigue on excessive use
- Loss of vision
- Existing neurological symptoms, such as weakness of arm, face, or leg, or dysphasia
- Excessive alcohol history
- Protruding eyeballs
- History of recent facial trauma
Red flag symptoms for dizziness
- Headache
- Ataxia
- Loss of consciousness
- Focal neurologic deficit
- Hearing loss
- Severe, continuous symptoms for >1 hour
Red flag symptoms for dyspepsia
- Iron deficiency anaemia
- Unintentional weight loss
- Dysphagia
- Persistent vomiting
- Epigastric mass
- Chronic GI bleeding
- Over 55 years with unexplained and persistent dyspepsia
- Low Hb, ferritin and/or mean corpuscular volume (MCV)
Red flag symptoms for epigastric pain
- Abdominal mass
- Central pulsatile mass with radiating pain
- Rebound tenderness with rigid abdomen
- Absent bowel sounds
- Acute pain and vomiting
- Ecchymosis of flanks or abdomen
Red flag symptoms for eye pain
- Sudden onset
- Visual loss
- Photophobia
- Fever
- Recent trauma
- Vomiting
- Associated red eye
- Contact lens wearer
- History of malignancy
- History of flashers or floaters
Red flag symptoms for facial pain
- Systemic upset
- Progressive pain, disability and distress
- Focal neurological deficit
- Weight loss
- Facial swelling or rash
- Vision disturbance
- Hearing loss/tinnitus/vertigo
- Unilateral nasal obstruction/discharge
Red flag symptoms for fever
- Persistent fever for >3 weeks with no clear cause
- Hx of foreign travel
- Persistent cough, SOB, haemoptysis
- New onset headache w/ or w/o focal neurological symptoms
- New onset headache w/ photophobia, neck stiffness
- New onset rashes
- New onset facial swelling/pain
- Persistent neck swelling/lymph glands for >6 weeks
- Night sweats for >6 weeks
- Unintentional weight loss
- New onset abdominal pain
- Bloody diarrhoea
- New onset urinary symptoms
- New onset testicular swelling
- New onset significant back pain
- New onset joint pain
- Recent HIV exposure
- New onset leg swelling
- Any obvious skin redness or breakdown
- Recent IVDU
- Recent chemotherapy
Red flag symptoms for haematuria
- Visible haematuria without urinary tract infection in patients aged 45 and over
- Visible haematuria that persists or recurs after successful Tx of UTI
- Non-visible haemarturia and either dysuria or raised WBC on blood test in pts aged 60 and over
- Abdominal mass clinically or on imaging
Red flag symptoms for haemoptysis
- Shortness of breath
- Reduced/absent breath sounds
- Malaise
- Weight loss
- Fatigue
- Back pain
- Calf pain/swelling
Red flag symptoms for dysphagia
(Dysphagia is a red flag symptom requiring urgent endoscopy 2WW)
- Drooling, inability to swallow saliva suggestive of complete obstruction - immediate referral may be needed
- Rapidly progressive dysphagia w/o neurological findings may suggest oesophageal malignancy
- Weight loss
- Focal neurological deficit
- Dysphagia and dyspepsia
- Hoarse voice
Red flag symptoms for headache
- Onset of headaches >50 years
- Thunderclap headache (SAH)
- Neurological signs or symptoms
- Meningism
- Immunosuppression or malignancy
- Red eye and haloes around lights - acute angle closure glaucoma
- Worsenign symptoms
- Symptoms of temporal arteritis
Red flag symptoms for hip pain
- Sudden onset
- History of trauma
- Any swelling
- Any deformity
- Inability to weight bear
- Any lumps/bumps felt in groin
- Night pain
- Noticeable groin pulsations
- Constipation or vomiting
- Haematuria
- Fever
- Lower limb neurological symptoms - weakness, numbness or tingling
- History of steroid use
- Testicular swelling
- Night sweats, unintentional weight loss, appetitie loss
- Hx of malignancy
Red flag symptoms for hoarse voice
- Persistent hoarseness (>3 weeks)
- Dysphagia
- Odynophagia
- Haemoptysis
- Otalgia w/ normal otoscopy
- Weight loss
- Excessive alcohol intake
- Smoking Hx
Red flag symptoms for jaundice
- Abdominal pain
- Palpable gall bladder
- Weight loss
- Fever
- Encephalopathy
- Evidence of bleeding from GI tract
- Coagulopathy
Red flag symptoms for widespread joint pain
- Night sweats
- Appetite loss
- Unintentional weight loss
- Joint swelling/redness and heat
- Early morning stiffness
- Persistent fever of more than 3 weeks
- Night pain
- New onset headaches
- Jaw claudication
- Scalp tenderness
- Significant lethargy
- Hx of IBD
- Hx of uveitis
Red flag symptoms for loss of appetite
- Significant unintentional weight loss
- New-onset dyspepsia, age >55
- Dysphagia
- Symptoms raising suspicion of malignancy
- Persistent low mood
- Features suggesting alcohol dependence
- Mini–Mental State Examination (MMSE) score, or equivalent, suggesting cognitive impairment
- Genitourinary, gastrointestinal or respiratory symptoms
- Loss of taste or smell contributing to the loss of appetite
Loss of consiousness red flag symptoms
- Preceding chest pain
- Preceding dyspnoea
- Preceding headaches
- Preceding palpitations
- Preceding abdominal pain
- Associated weakness of arm, face or leg
- Associated with exercise or posture
- Blood loss
- Evidence of GI bleeding
- Associated tongue biting, urinary incontinence or prolonged limb jerking
- New medication
- Preceding lightheadedness
- Known diabetic on an oral hypoglycaemic or insulin
Red flag symptoms for muscle weakness
- Persistent weakness (> 4 weeks)
- Muscle wasting
- Loss of power
- Recurrent falls
- Unusual paraesthesiae
- Visual symptoms
- Significant, unintentional weight loss
- Night sweats
- Loss of appetite
Red flag symptoms for muscle pain
- > 4 weeks duration
- History of significant trauma
- Early morning symptoms
- Persistent fevers/systemic upset
- Abnormal rashes
- Associated weakness
- Muscle wasting
- Significant unintentional weight loss
- Joint pains
- Swelling or redness
- Significant fatigue
- New numbness or power loss in a limb
- Loss of bowel or bladder control
Red flag symptoms for neck pain
- Significant preceding trauma or neck surgery
- Systemic upset (unintentional weight loss, night sweats, fevers)
- Severe pain
- Nocturnal pain
- Relatively young (<20 years) or old (>55 years)
- Signs of spinal cord compression
- Significant vertebral body tenderness
- History of TB, HIV, cancer or inflammatory arthritis
- Severe headache +/– fever +/– non-blanching rash
Red flag symptoms for night sweats
- Significant unintentional weight loss
- Any symptoms warranting a two-week wait referral (see cancer risk assessment tools)
- A history of foreign travel
- Risk factors for HIV
- Palpable lymph glands
- Risk factors for TB
- Recurrent bacterial infections requiring antibiotics
- History of alcohol excess or recreational drug use
- Signs of meningeal irritation (meningism), such as neck stiffness, photophobia, headache
- Haemoptysis
- Symptoms suggestive of COVID-19, such as cough, anosmia, dysgeusia
- Persistent nose bleeds, bleeding gums or petechiae
Red flag symptoms for numbness
- Sudden or rapid onset
- Confusion or loss of consciousness
- Slurred speech
- Change in vision
- Saddle anaesthesia
- Loss of bladder or bowel control
- Difficulty walking
- Numbness after a head, neck or back injury
Red flag symptoms for oedema
- Periorbital oedema in a child
- Change in medication
- Accompanying breathlessness
- Pain, hyperpigmentation, absent leg pulse
- Signs of sepsis
- High blood pressure
Red flag symptpms for palpitations
- Chest pain
- Acute dizziness or syncope
- Shortness of breath
- Hypotension
- Focal neurological symptoms
Red flag symptoms for persistent cough
- Persistent cough for more than three weeks
- Pleuritic chest pain
- Dyspnoea
- Haemoptysis
- Persistent nocturnal cough
- Wheeze
- Recurrent chest infections
- Coughing up phlegm every morning for more than three months of the year
- Unintentional weight loss
- History of night sweats
Red flag symptoms for pharyngitis
- Persistent sore throat for >6 weeks
- Persistent cough, fever, loss of taste and loss of smell
- Excessive drooling
- Trismus
- Unilateral facial swelling
- Dysphagia
- Dyspnoea
- Immunosuppressant medication, such as carbimazole and monoclonal antibodies (MABs)
- Persistent unilateral tonsillar enlargement
- Neck stiffness
- Photophobia
- Non-blanching rash
Red flag symptoms for rectal bleeding
- Weight loss
- Change in bowel habit, especially diarrhoea and/or increased frequency
- Iron-deficiency anaemia
- Abdominal mass
- Rectal/anal mass
- Faecal occult blood
Respiratory tract infections red flag symptoms
- Cough >3 weeks
- Persistent cough in a smoker
- Haemoptysis
- Persistent hoarseness >3 weeks
- Persistent sore throat
- Persistent palpable neck lumps
- Persistent unilateral enlarged tonsil
- Difficulty completing sentences
- Difficulty swallowing (particularly own saliva)
- Shortness of breath
- Pleuritic chest pain
- Headache, photophobia and neck stiffness
- Non-blanching rash
- Nasal flaring/grunting in babies
- Recession of intercostal muscles in young children
Skin rash red flag symptoms
- Rash covering more than 90% of a person’s body surface area
- Punched-out lesions in a person with eczema
- Fever
- An unwell patient (adult or child)
- Diarrhoea
- Nausea and vomiting
- Headache
- Photophobia
- Non-blanching rash
- Arthralgia and muscle pains
- Pharyngitis
- Blisters and bullae
- Scalded skin appearance
- Skin lesions
Swollen calf red flag symptoms
- Recent immobility or surgery
- 3cm discrepancy compared to the other calf
- Unilateral swelling
- Calf pain/tightness/redness
Tingling red flag symptoms
- Onset after trauma, surgery or systemic infection
- Multiple areas involved or progressive symptoms
- Additional behavioural or memory changes, or dizziness/headaches
- Fever or other systemic upset
- Disturbances of autonomous nervous system or objective muscular weakness
- Patient is at high risk because of age, existing chronic conditions or lifestyle factors
Tinnitus red flag symptoms
- Sudden and pulsatile tinnitus
- Significant neurological signs/symptoms
- Severe vertigo
- Sudden unexplained hearing loss
- Developing after head injury
- Severe functional or psychological distress
Tired all the time red flag symptoms
- Significant unexplained weight loss
- Lymphadenopathy with features of malignancy or infection such as HIV
- Other features of malignancy - haemoptysis, dysphagia, rectal bleeding, altered bowel habit, breast lump, postmenopausal bleeding (also see NICE guidance on suspected cancer2)
- Muscle or joint pain suggestive of inflammatory joint or connective tissue disease
- Localising or focal neurological signs
- Suicidal ideation
Tremor red flag symptoms
- Sudden onset
- Progressive
- Stepwise (suggestive of stroke or MS)
- Neurological deficits
- Age under 50 years in the absence of family history of essential tremor
Urinary retention red flag symptoms
- Pain
- Painless acute retention
- Haematuria or clots
- History of prolonged bladder outflow obstruction
Vomiting red flags
- Severe abdominal pain – consider GI obstruction, acute pancreatitis or cholecystitis. If guarding, peritonism and absent or scanty bowel sounds are found, think acute abdomen.
- Rectal bleeding – consider GI inflammation or malignancy
- Haematemesis – peptic ulcer, Mallory-Weiss tear, oesophageal varices, malignancy
- Acute or focal neurological symptoms – CNS infection, tumour, stroke. Beware the patient with vomiting and unexplained headache
- Chest pain or other features of acute coronary syndrome. Ischaemic gastroparesis should be considered in older patients with known atherosclerotic disease
- Anorexia or weight loss may indicate cancer. Also consider psychiatric causes
- Shock, volume depletion or life-threatening illness – consider adrenal insufficiency, which is a medical emergency, with nausea, vomiting, volume depletion and low sodium
Unintentinal weight gain red flag symptoms
- Rapid onset
- Recurrent hypoglycaemia
- Headache
- Uncontrollable hunger
- Shortness of breath
- Abdominal pain
- Hair or skin change
- Constipation or cold intolerance
- Menstrual disturbance
- Mood disturbance