Red Eye - Exam 3 Flashcards
**_____ COPIOUS PURULENT DISCHARGE ; eyes can be “stuck shut” in the morning. can be ___ or ____. How is it transmitted?
CONJUNCTIVITIS
unilateral or bilateral
TRANSMITTED VIA DIRECT CONTACT
FINGERS, TOWELS, HANDKERCHIEFS, CONTAMINATED EYE DROPS
**_____ is the MC cause of conjunctivitis in adults. ____ in children. ____ who wear contacts.
Staph Aureus in adults
S Pneu in children
Pseudomonas in those who wear contacts
What is the treatment of choice for conjunctivitis in NONcontact lense wearers? For severe infection/contact lens use ______
erythromycin ophthalmic ointment or trimethoprim-polymyxin B drops (POLYTRIM)
TOPICAL FLUOROQUINOLONE
VIGAMOX OR MOXEZA (MOXIFLOXACIN)
OFLOXACIN OPHTHALMIC (OCUFLOX / FLOXIN)
CIPROFLOXACIN OPHTHALMIC
gonococcal infections in the eye are treated with _____. Chlamydial infections are treated with _____.
ROCEPHIN (CEFTRIAXONE) 1G IM – SINGLE DOSE can add ERYTHROMYCIN OR BACITRACIN
1G AZITHROMYCIN PO – SINGLE DOSE
**____ is the MC infectious cause of blindness (preventable blindness)
chlamydial
_____ pulls the eyelid inside out
Trachoma
USUALLY BILATERAL
COPIOUS WATERY DISCHARGE
FOREIGN BODY SENSATION
TYPICALLY LASTS 10 DAYS
ASSOCIATED WITH PHARYNGITIS, FEVER, MALAISE, PREAURICULAR ADENOPATHY aka flu like s/s
What am I?
What is the MC?
What is the treatment?
viral conjunctivitis
MC: adenovirus
supportive care: cold compress to reduce discomfort
pt education on hygiene
ITCHING
TEARING
REDNESS
STRINGY DISCHARGE
OCCASIONALLY PHOTOPHOBIA AND VISUAL LOSS
COBBLESTONE PAPILLAE NOTED ON EXAM
HYPEREMIA (bloodshot look to eye) AND CHEMOSIS (conjunctiva looks bulgy coming out of eye)
What am I?
**What are the 2 slum dunk characteristics?
Allergic conjunctivitis
**stringy discharge and cobblestone papillae
What is the treatment for mild-moderate allergic conjunctivitis? Severe?
TOPICAL ANTIHISTAMINES
ALAWAY (KETOTIFEN), PATANOL OR PATADAY (OLOPATADINE)
or
topical NSAIDS: diclofenac, ketorolac
severe: topical corticosteroids: LOTEPREDNOL (Alrex, Lotemax)
When would you NOT want to give steroids on a case of allergic conjunctivitis?
NO CORTICOSTEROIDS IF H/O OR SUSPECTED HSV
MAY CAUSE EXACERBATION
What does the uvea consist of?
the layer and structures of the eye beneath the sclera.
(1) the iris (and pupil)
(2) the ciliary body (secretes the aqueous humor)
(3) the choroid
the _____ is the layer of blood vessels and CT between the sclera and retina
choroid
Uveitis: anterior portion consists of ___ and ____.
The posterior portion consists of _____
Anterior portion:
Iris
Ciliary Body
Posterior portion:
Choriod
What are the different types of INTRAOCULAR INFLAMMATION OF THE UVEA? **What is the MC type?
ACUTE OR CHRONIC
NON-GRANULOMATOUS VS. GRANULOMATOUS
ANTERIOR OR POSTERIOR
ACUTE NONGRANULOMATOUS ANTERIOR UVEITIS
Describe a non-granulomatous uveitis. What is the predominant cell type?
Inflammation with no epithelial or giant cells
PRESENTS ACUTELY
UNILATERAL PAIN
REDNESS
PHOTOPHOBIA
VISUAL LOSS
PMN cells
Describe a granulomatous uveitis. What is the predominant cell type?
inflammation noted with histiocytes
INDOLENT
SLOW GROWING
BLURRED VISION
MILDLY INFLAMED EYE
RECURRENT
macrophages
What are some causes of acute NON-GRANULOMATOUS ANTERIOR?
ACUTE = PRIMARILY IMMUNOLOGIC aka autoimmune causes
HLA-B27 RELATED CONDITIONS
ANKYLOSING SPONDYLITIS
REACTIVE ARTHRITIS
PSORIASIS
ULCERATIVE COLITIS
CROHN’S DISEASE
What are some causes of chronic NON-GRANULOMATOUS ANTERIOR?
JUVENILE IDIOPATHIC ARTHRITIS
What are some causes of GRANULOMATOUS ANTERIOR uveitis?
SARCOIDOSIS
TOXOPLASMOSIS
TUBERCULOSIS
HIV
SYPHILIS
“SALT AND PEPPER” FUNDUS
HERPES
OCULAR TRAUMA
**“INFLAMMATORY CELLS AND FLARE” (proteins) WITHIN THE AQUEOUS is classic _____. How do you dx it? What will you see in severe cases?
anterior uveitis
slit lamp exam
SEVERE CASES = HYPOPYON
PUS IN THE ANTERIOR CHAMBER
In uveitis, CELLS MAY ALSO BE SEEN ON THE CORNEAL ENDOTHELIUM, what are they known as? in granulomatous you see _____. In non-granulomatous you seen _____
KERATIC PRECIPITATES (KPS) aka inflammatory cellular deposits
GRANULOMATOUS = LARGE KPS
IRIS NODULES MAY BE SEEN
NON GRANULOMATOUS = KPS ARE SMALLER
NO IRIS NODULES
in posterior uveitis, INFLAMMATORY LESIONS MAY BE PRESENT IN THE ____ or ____. What will new lesions look like? old lesions?
RETINA OR CHOROID
NEW LESIONS:
YELLOW WITH INDISTINCT MARGINS
RETINAL HEMORRHAGES
OLD LESIONS:
DEFINITE MARGINS
COMMONLY PIGMENTED
GRADUAL VISUAL LOSS—-SLOWER IN ONSET
MAY BE DUE TO VITREOUS HAZE AND OPACITIES
CAN PRESENT WITH FLOATERS AS WELL
BILATERAL INVOLVEMENT COMMON
What am I?
What is the cause?
posterior uveitis
idiopathic
autoimmune
pars planitis
infectious causes
What is pars planitis?
disease of the eye between the iris and choroid
What is the treatment for anterior uveitis?
refer to ophthalmology
**topical corticosteroids
dilation of the pupil to relieve discomfort: reduces painful spasms of ciliary muscles
What is the treatment for posterior uveitis?
systemic steroids
pupil dilation NOT needed
if infectious, treat with appropriate abx
______ is inflammation of the cornea. What are the different types?
keratitis
bacterial
viral
acanthomoeba
fungal
**____ are at the highest risk of developing bacterial keratitis. What is an additional cause? What is the MC pathogens?
contact lens wearers (especially those who wear them overnights)
corneal trauma
**PSEUDOMONAS
MORAXELLA
STAPHYLOCOCCI (INCLUDING MRSA)
STREPTOCOCCI
PT WILL COMPLAIN OF FOREIGN BODY SENSATION
TROUBLE KEEPING EYE OPEN
CORNEA APPEARS HAZY WITH ULCER AND ADJACENT STROMAL ABSCESS
HYPOPYON OFTEN PRESENT
What am I?
How do you dx?
What is the treatment?
bacterial keratitis
ULCER IS SCRAPED TO RECOVER MATERIAL FOR GRAM STAIN AND CULTURE
refer to ophthalmology
EMPIRICALLY WITH FLUOROQUINOLONES DROPS: OFLOXACIN 0.3%, CIPROFLOXACIN 0.5%, VIGAMOX, MOXEZA
HOURLY (DAY AND NIGHT) FOR THE FIRST 48 HOURS
Then tailor tx based on culture results
What are some causes of viral keratitis? Why is it dangerous?
PRIMARY OCULAR HERPES SIMPLEX-> can cause blindness
can cause blindness->TRAVELS TO SENSORY GANGLIA WHERE LATENCY DEVELOPS, VIRUS CAN COLONIZE THE TRIGEMINAL GANGLION
RED EYE
PHOTOPHOBIA
FOREIGN BODY SENSATION
WATERY DISCHARGE
REACTIVATED VIRUS ENTERS CELLS OF CORNEA
PRIMARY INFECTION MAY MANIFEST AS EYELID, CONJUNCTIVAL, AND CORNEAL ULCERATION
DENDRITIC (BRANCHING) CORNEAL ULCER
What am I?
What is the slam dunk s/s? How do you dx it?
Herpes simplex keratitis
**DENDRITIC (BRANCHING) CORNEAL ULCER
CORNEAL ULCERS IDENTIFIED WITH FLUORESCEIN STAIN
What is the treatment for HERPES SIMPLEX keratitis?
URGENT REFERRAL TO OPHTHALMOLOGIST
TOPICAL AND/OR ORAL ANTIVIRALS: treat until 1 week after lesions heals
ACYCLOVIR 400MG FIVE TIMES DAILY
ACYCLOVIR 3% OINTMENT