red eye and adnexal oncology Flashcards

1
Q

Give a differential diagnosis for conditions that cause red eye

A
• Uveitis (inflammation in the eye)
- No pain- mild pain
- Pericorneal redness or none
• Conjunctivitis (bacterial)
- No pain to itchy
- Peripheral or diffuse redness
• Conjunctivitis 
- No pain to itchy
- Peripheral or diffuse redness
• Conjunctivitis (allergic)
- No pain to itchy
- Peripheral or diffuse redness
• Conjunctivitis (all): Bulbar (eyeball) and palpebral (lid) can affect one or both
• Sclerites
- Sever/ boring pain
- Sectoral/ diffuse redness
• Acute glaucoma
- Severe with a headache
- Pericorneal redness
• Keratitis/ corneal ulcer 
- Sever pain and eyes closing
- Pericorneal redness
• Corneal abrasion
- Heals quickly
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2
Q

Explain uveitis

A
  • Symptoms: No pain- mild pain, pericorneal redness or none, minimal discharge/ none, blurred vision
  • Causes: Idiopathic, associated with systemic disease (ankylosing spondylitis, Behcet’s disease, sarcoidosis, wegner’s, systemic lupus erythematosus) , infection (TB, syphilis, toxoplasma, herpes simplex, Lyme’s disease, CMV), masquerade (intraocular lymphoma, leukaemia)
  • Treatment: treat infection, topical anti-inflammatories, systemic steroid, systemic immunosuppressants
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3
Q

What are the symptoms of conjunctivitis?

A
  • No pain to itchy
  • Peripheral or diffuse redness
  • Yellow discharge (bacterial)
  • Watery discharge (idiopathic)
  • Mucous discharge (allergic)
  • Normal vission
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4
Q

What are the symptoms of sclerites?

A
  • Severe/ boring pain
  • Sectional/ diffuse redness
  • No discharge
  • Normal vision
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5
Q

What are the symptoms of acute glaucoma?

A
  • Severe pain with a headache
  • pericorneal redness
  • Could have discharge but might not
  • Vision is lost
  • Fixed, dilated pupils
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6
Q

What are the symptoms of a corneal ulcer?

A
  • Severe pain and eyes closing
  • Pericorneal redness
  • Might have discharge
  • Lost vision
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7
Q

Explain preseptal cellulitis

A
  • Features: Pain, redness, lid swelling, systemically unwell

- Causes: Lid cyst or insect bite

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8
Q

Explain orbital cellulitis

A
  • Features: Pain, redness, lid swelling, systemically unwell, double vision/ limitation in EOEM, conjunctivitis/ chemosis, exophthalmos, blurred vision
  • Common causes: sinusitis, dental infections, haematological spread
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9
Q

Describe some adnexal and orbital pathologies

A
• Eyelid tumours (very common)
• Lacrimal drainage tumours (very rare)
• Orbital tumours (very rare and most are benign)
- Capillary haemangioma (benign)
- Cavernous haemangioma (benign)
- Pleomorphic adenoma (benign)
- Optic nerve glioma (benign)
- Lymphoma (malignant)
- Metastatic regional spread (malignant) 
- Rhabdomyosarcoma(malignant)
- Lacrimal gland carcinoma (malignant)
- Osteosarcoma (malignant)
- Liposarcoma (malignant)
- Primary melanoma (malignant)
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10
Q

Explain squamous cell papilloma

A
  • Benign
  • Pedunculated or sessile (broad-based)
  • Characteristic “raspberry” texture
  • Usually viral
  • Treatment: Rx excision or laser ablation
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11
Q

Explain basal cell papilloma

A
  • Benign
  • Greasy, brown, flat, round/oval
  • Similar texture to squamous cell papilloma
  • “stuck on” appearance
  • Unrelated to sun exposure
  • Treatment: Rx excision
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12
Q

Explain pyrogenic granuloma

A
  • Benign
  • Fast growing, highly vascularised granuloma
  • May follow surgery, infection, trauma
  • Erythematous pedunculated mass
  • Treatment: Rx excision
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13
Q

Explain actinic keratosis

A
  • Common pre-malignant condition, though relatively rare on eyelids
  • Flat, scaly, hyperkeratotic skin, occasionally forms cutaneous horn
  • Related to exposure to sunlight
  • Treatment: Rx excision or medical treatment
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14
Q

Explain keratoacanthoma

A
  • Rare, “squamous cell carcinoma in-situ”
  • Rapidly growing in otherwise healthy skin
  • Pink papule, hyperkeratotic crater
  • Sun exposure, immunosuppression
  • Treatment: Rx excision
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15
Q

Explain basal cell carcinoma

A
  • Common
  • Pale skin and sun exposure
  • Features: Slow, inexorable growth over months; usually non-pigmented, elevated, ulcerated; pearly, rolled, irregular boarder; telangiectasia; lack of tenderness
  • Nodular: common, classic firm pearly nodule
  • Ulcerative: common, may progress from nodular, cycles of crusting and bleeding
  • Morpheaform/ infiltrative: less common, indurated plaques
  • Treatment: excision, Mohs surgery, topical (imiquimod, efudex), chemotherapy, radiotherapy, photodynamic therapy
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16
Q

Explain squamous cell carcinoma

A
  • Scaly surface over a thick plaque
  • Growth over weeks rather than months
  • Treatment: Rx excision
17
Q

Explain sebaceous gland carcinoma

A
  • Nodular, indurated lid margin
  • Yellowish discolouration (lipid content)
  • Pagetoid spread along conjunctiva, map Bx
  • Biopsy is best diagnostic technique
  • Treatment: Rx excision
18
Q

Explain malignant melanoma

A
  • Lentigo maligna: flat, variably pigmented macule
  • Superficial spreading: slightly raised pigmented plaque
  • Nodular: vertically invasive (may be amelanotic)