Red cell immunology/Donor selection/Blood components Flashcards
1
Q
Types of donors?
A
- voluntary
- replacement
- directed
- autologous
- apheresis
2
Q
reasons for temporary deferral?
A
- tattoo
- medications- antibiotics, aspirin, vaccination
- pregnancy
- malaria exposure
3
Q
reasons for permanent deferral?
A
- HIV positive
- hepatitis infection
- hematological malignant disease- leukemia, lymphoma and multiple myeloma.
- chronic renal disease
- cardiac disease due to hypertension
4
Q
how much is in a unit of whole blood?
A
450 ml
note: 63 ml of antiocoagulant
5
Q
whats the most common used anticoagulant in the collection of blood?
A
CPDA-1
6
Q
Red cells Red cells stored in CPDA1 are kept for 35 days at what temp?
A
4 *C
7
Q
A transfusion of red cells is considered to be satisfactory if more than 75% of the cells survive within the circulation for at least 24 hr. T or F.
A
T
8
Q
During storage, what changes in composition occur resulting from red cell metabolism?
A
- decrease ATP
- increase red cell destruction
- decrease tissue oxygenation (decline in 2,3 DPG)
- increased potassium concentrate in plasma
- hypocalcemia
- decreased activity of FV and FVIII
