Recon Flashcards
What is the most common cause of early revision in hip resurfacing?
periprosthetic fracture
most common
What linear wear rate has been associated with osteolysis and loosening?
> 0.1 mm/year
5 variables leading to PE wear characteristics
PE thickness:
- should be >8mm
Articular surface design:
- higher congruity/contact surface area leads to lower contract stress and better wear characteristics
Kinematics:
- ie knee kinematics. Change them to get most congruous implant
PE sterilization:
- Gamma radiation Sterilization in oxygen depleted environment is best
- Then package in vacuum, argon or nitrogen environment
PE machining
- Best is with direct-compression molding
4 complications of free fibula vascularized bone graft?
- sensory deficit
- motor weakness
- FHL contracture
- tibial stress fracture from side graft is taken
5 Considerations in sickle cell in arthroplasty
Pre-op
Check for osteomyelitis
Avoid sickle cell crisis (lots of fluids, oxygenate, avoid acidosis)
CHF often present with chronic anmeia
pre-op transfusion/plasmaphoresis
Intraop
Protrusio
Widened canal (marrow hyperplasia)
poor bone quality
osteonecrosis
Postop
Higher infection rates (no salmonella)
Do NOT need to cover for salmonella
Higher rates of dislocation
Techniques to reduce nerve injury in THR for DDH?
- good pre-operative planning
- limb lengthening
- subtrochanteric osteotomy
- intra-operative wake-up test
- neurophysiologic intraoperative monitoring
- downsizing implant components if presenting with deficits peri-operatively
On an AP xray, what landmarks are most useful for assessing acetabular cup position?
- medial border of cup should approximate the ilioischial line and lie close to the teardrop
- inferior border of cup should be at level of inferior teardrop line
Postpartum female with hip pain - what do you think of?
transient osteoporosis of hip
5 ways to avoid failure of cemented femoral stem.
- smooth stem
- > 2 mm mantle
- rigid stem
- centralized stem
- No defects of mantle
Two main contraindications to hip osteotomy?
Restricted hip motion
Advanced OA
List 4 devices available for fixation of a TKA periprosthetic femoral fracture
condylar buttress plate (non-locking)
locking supracondylar plate
blade plate
dynamic compression screw
Most common nerve injury with hip scope?
Pudendal from traction
Describe femoral rollback
Lateral condyle has a larger curvature of radius so as you flex & extend the knee, the lateral condyle will pivot about the medial side
Conceptually, what is the ideal patient to use constrained components in THA?
In patients with a soft tissue insufficiency not amenable to repair or augmentation
it is NOT to correct for malalignment
Saggital balancing:
Flexion: Loose
Extension: Tight
What do you do?
resect femur + thicker poly
or
release capsule posteriorly and thicker poly
Differentiate adhesive, abrasive, and third body wear.
adhesive wear
most important in osteolytic process
microscopically PE sticks to prosthesis and debris gets pulled off
abrasive wear
cheese grater effect of prosthesis scraping off particles
third body wear
particles in joint space cause abrasion and wear
Indications for a hinged knee prosthesis?
- global instability
- massive bone loss in a neuropathic joint
- oncologic procedures
- hyperextension instability
3 benefits of increasing offset?
- increased soft-tissue tension
- decreased impingement
- decreased joint reaction force
Risks of patellar periprosthetic fracture
patellar osteonecrosis
asymmetric resection of patella
inappropriate thickness of patella
implant related
- central single peg implant
- uncemented fixation
- metal backing on patella
- inset patellar component
General workup algorithm for MoM patients
Yearly assessment (x-ray, blood levels)
If high risk: get advanced imaging (MARS MRI)
Revision if:
Symptomatic, osteolysis, poor cup abduction angle, increasing metal ion level, pseudotumour
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5 risks of HO in TKA
Periosteal stripping of anterior femur
Male
Obesity
Post-traumatic
Hypertropic osteophystes preop
Arthropathy (DISH, AS)
Paget’s
Cementless components
Approach: iliofemoral > Kocher > II
Manipulation post op
(NOT RA)
in DDH THA, name 3 ways to decrease sciatic nerve palsy
Visualize/palpate for tension
lengthen 4cm or 15-20% of length (some say
Neuromonitoring
Risk factors for Hip OA
Modifiable
Articular cartilage
Muscle weakness
Heavy physical stress at work
High impact sporting activities
Non-modifiable
Female
Increased age
Genetics
Developmental/acquired deformities
Hip dysplasia
SCFE
LCP
2 ways of testing for nickel sensitivity?
- patch testing
- lymphocyte transformation test (LST)
2 indications for chronic suppressive antibiotics in periprosthetic infection
Patient too sick to undergo surgery
Complex arthroplasty with huge revision needed
Name 8 risks of AVN of the hip (or of anything)
“ASEPTIC”
Alcoholism/AIDS/Immnosuppressed
Steroids/Sickle cell
Erlenmeyer flask (Gaucher)
Pancreatitis
Trauma
Idiopathic
Caissons (The Bends)
Hypercoaguable state
Risks for knee OA
Modifiable
Articular trauma
Occupation: repetitive knee bending
Muscle weakness
Large body mass
Metabolic syndrome
- Central (abdominal obesity)
- Dyslipidemia (high triglycerides & high LDLs)
High BP
Elevated fasting glucose
Non-modifiable
Female
Increased age
Genetics
Race
African american males are the least likely to receive total joint replacement when compared to whites and Hispanics
What procedure has the lowest reoperation rates for patients with unicompartmental OA?
TKA
3 surgical options for AVN femoral head in post-collapse:
Rotational osteotomy (may be done precollapse). Only if small lesion
Resurfacing
THA
Arthrodesis
Describe a differential MCL release in varus TKA
Posterior oblique tight in extension: release if tight in extension
Anterior portion tight in flexion: release if tight in flexion
(Small/large) head:neck ratios in THA ______ dislocation risk by increasing ______ distance
Large
decreases
Jump
5 risk factors for squeaking with ceramic bearings?
- edge loading
- impingement and acetabular malposition
- third-body wear
- loss of fluid film lubrication
- thin, flexible (titanium) stems
What is the main determinant for number of wear particles created?
Volumetric wear
V=3.14r^2 * w
(the circular area of the head times the rate at which it penetrates medially)
w = linear wear rate
Optimal micromotion in biologic fixation?
Rule of 50’s
- pore size 50-300um
- preferably 50-150um
- porosity of 40-50%
- gaps <50um
- micromotion <150um
What type of inflammatory response does MoM create?
Lymphocytic (it’s a hypersensitivity response)
vs. macrophage for PE
What is the mechanism of failure for fracture of cemented femoral stems?
Cantilever bending.
Cemented stems are thinner and more prone to breaking.
3 causes of TKA periprosthetic femoral fractures
poor bone quality
Mechanical stress riser
Neurologic disorders
Name 5 risk factors for dislocation after THA
female
Treatment for AVN of femoral head
Treatment for acute fracture
inflammatory arthritis
age > 70
What is a complication unique to cermaic bearings and what is the cause?
stripe wear
occurs during lift-off separation of the head during gait (edge loading)
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
glucosamine and chondroitin
STRONG evidence AGAINST
Two risks with not resurfacing patella in THR?
Higher risk of anterior knee pain
Higher risk of secondary resurfacing
(No difference in complications such as AVN, fracture, ect)
Well fixed cup with a broken locking mechanism, what is the best option?
Bone graft acetabular defects and cement in a new liner
patella baja in setting of Revision TKA. What do you do for exposure?
Tibial tubercle osteotomy so that you can realign patella at same time
5 complications of hip resurfacing?
periprosthetic femoral neck fracture
implant loosening (aseptic)
HO
increased metal ion level
Pseudotumour
5 Risks of supracondylar fracture post TKA
Rheumatoid arthritis
chronic steroid therapy
Parkinson’s disease
osteopenia
female gender
Surgical options for a stiff TKA (4)
MUA
arthroscopic or open adhesiolysis +/- MUA
quadricepsplasty
component revision.
By how much does a hip fusion decrease efficiency of gait?
50%
Femoral rollback clinically improves what?
improves quadriceps function and range of knee flexion by preventing posterior impingement during deep flexion
3 indications for ETO as per JAAOS 2013 (Paprosky)
Significant varus remodeling
a well fixed uncemented implant
a long column of cement below the stem
What effect does osteoprotegrin have on bone turnover?
Inhibits RankL thereby inhibitng bone turnover.
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4 ways to decrease free radicals in polyethylene production
Vitamin E
Mechanical deformation
Low doses of radiation alternated with annealing
Final sterilization in ethylene oxide gas
How long do ESR and CRP take to return to normal following surgery?
CRP = 21 days
ESR = 90 days
4 risks for creating stress shielding
stiff femoral stem: (most important risk factor)
large diameter stem
extensively porous coated stem
greater preoperative osteopenia
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
rehabilitation, education and wellness activity
STRONG evidence FOR
POsition of hip arthrodesis
20-35 degrees of flexion
0-5 degrees adduction
5-10 degrees ER (equal to contralateral)
Avoid abudction as it creates pelvic obliquity and increased back pain
How thich do you want a cement mantle?
At least 2 mm thick
3 complications unique to ceramic heads?
- fracture
- sqeaking
- stripe wear
hydroxyapatite coating is what kind of agent?
What effect on biologic fixation does it have?
osteoconductive
Allows more rapid closure of gaps
shorter time to biologic fixation (in animals, and in humans in some studies)
What are the five goals of revision total knee surgery?
- extraction of components with minimal bone loss and destruction
- restoration of bone deficiencies
- restoration of joint line
- balance knee ligaments
- stable revision implants
Surgeon wants to use extramedullary referencing for tibia cuts in a total knee arthroplasty. If he ignores the rotational mismatch between the ankle and the tibial tubercle, what will the result?
a. No coronal malalignment
b. Varus malalignment on coronal
c. Valgus malalignment on coronal
d. Increase posterior slope cut into tibia
b. Varus malalignment on coronal
What type of arthroplasty will worsen your golf game?
TKA: increases handicap
THA: no change
Name 6 tools to have on hand during revision arthroplasty (Paprosky Jaaos 2013)
Manufacturere specific explant tools
flexible osteotomes
trephines
high speed burrs
ultrasonic cement removal instruments
universal extraction tools
Risk factors for dislocation following THR?
- prior hip surgery (greatest risk factor)
- female sex
- >70-80 years of age
- posterior surgical approach
- repairing capsule and reconstructing external rotators brings dislocation rate close to anterior approach
- malpositioning of components
- ideal positioning of acetabular component is 40 degrees of abduction and 15 degrees anteversion give or take 10 degrees in each position
- in general, excessive anteversion increases risk of anterior hip dislocation; excessive retroversion increases risk of posterior hip dislocation
- spastic or neuromuscular disease (Parkinson’s)
- drug or alcohol abuse
- decreased offset (decreases tissue tension and stability)
- decreased femoral head to neck ratio
2 risks for increased MoM serum ion levels
Smaller component size
Cup abduction angle >55
In sciatic nerve injury post-THA, what percentage fully recover?
80% remain symptomatic
What do you do for intra-operative calcar fracture during THR?
stem removal, cable wiring of the calcar, and re-insertion of the primary stem
Options for cartilage defects in an adult without end stage OA and no major coronal deformity. (List By Size)
femoral condyle defect
correct malaligment, ligament instability, meniscal deficiency
measure size
< 4 cm2 = microfracture or osteochondral autograft transfer (pallative if older/low demand)
> 4 cm2 = osteochondral allograft transplantation or autologous chondrocyte implantation
patellofemoral defect
address patellofemoral maltracking and malalignment
measure size
< 4 cm2 = microfracture or osteochondral autograft transfer
> 4 cm2 = autologous chondrocyte implantation (microfracture if older/low demand)
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List 4 options for a Vancouver B2 periprosthetic fracture
Cylindrical, distally fitted monoblock stem (old gold standard)
Modular, distally fitted, tapered stem (Wagner style - new gold standard)
Cemented stem
Allograft-prosthetic composite
Tumour replacement
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
NSAIDS
STRONG evidence FOR
2 contraindications for TT osteotomy
Osteolysis
Proximal tibial osteoporosis
How do you deal with the mechanical axis when doing a UKA?
Undercorrect the mechanical axis by 2-3 degrees
do NOT want it to be in neutral or varus as these are associated with poor outcomes
MCL rupture during TKA. What are 2 options?
Suture repair + PS/CR + hinged knee brace x 6 weeks
Unhinged constrained knee (VVC)
Elevation of the joint line by how much will lead to motion problems?
8mm
What is the effect of the routine use of antbiotic loaded cement in TKA?
Increased risk of aseptic loosening
6 risks of femoral neck fracture in hip resurfacing
notching of the femoral neck
osteoporotic bone
large areas of preexisting osteonecrosis
femoral neck impingement (from malaligned acetabular component)
female sex
varus positioning of femoral component
6 risk factors for nerve injury in THR?
- developmental dysplasia of the hip
- revision surgery
- female gender
- limb lengthening
- posttraumatic arthritis
- surgeon self-rated procedure as difficult
disruption of medial & lateral inferior geniculate arteries will results in what perioperatively during TKA?
patellar tendon rupture
Superior geniculate artery for quad tendon
7 techniques for femoral revision
- Primary total hip components – minimal loss of metaphyseal bone
- Extensively porous coated stems – metaphyseal bone loss with intact diaphysis
- Monoblock calcar revision stems
- Modular tapered diaphyseal fit stems
- Impaction grafting
- Allograft prosthetic composites
- Modular oncology stem
Fracture of ceramic on ceramic THA. What must you do at revision?
Replace with another ceramic component.
Despite thorough I&D, there will be ceramic debris left over that will cause massive 3rd body wear of any other type of component
Name the three most common hip scope portals, their landmarks and associated nerve injuries.
- Anterior = LCFN
- Intersection between superior GT and ASIS
- Anterolateral = SGN
- 2 cm anterior, 2 cm superior to AS aspect of GT
- Established first
- Posterolateral = Sciatic
- 2 cm posterior to tip of GT
Correction of what deformity has the highest rate of peroneal nerve palsy in TKA
valgus & flexion
Do you need to cover for salmonella after arthroplasty in sickle cell?
No
While there are increased infection rates overall, there were no salmonella infections
What is the most common complication of THA performed for salvage of a failed internal fixation for pathologic proximal femur fracture?
Deep joint infection
4 indications for constained liner in THR.
1) cases with no identifiable cause for instability
2) abductor deficiency
3) patients with neuromuscular disorders
4) recurrent instability with well positioned components
Contraindications to CR knee (3)?
- varus deformity > 10 degrees
- valgus deformity > 15 degrees
- No PCL
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
Viscosupplementation
STRONG evidence AGAINST
4 surgical techniques to treat a recurrant dislocator (hip) in revision setting.
- 1 realign components
- indicated if malalignment explains dislocatio
- 2 head enlargement
- optimize head-neck ratio
- (Dual mobility is similar option)
- 3 trochanteric osteotomy and advancement
- places abductor complex under tension which increases hip compression force
- 4 conversion to a constrained acetabular component
What is the proposed benefit of a mobile bearing knee?
Tibial poly rotates on the baseplate. This creates a larger surface area for contact and thought to decrease contact pressure and reduce wear.
5 indications for knee fusion?
- painful ankylosis after infection or trauma
- neuropathic arthropathy
- tumor resection
- salvage for failed TKA (most common)
- loss of extensor mechanism
Order of release in flexion contacture in TKA
osteophytes
posterior capsule
gastrocnemius
Risks of blood loss & allogenic transfusion in TKA (4)
Slower physical recovery
higher rates of postoperative infection
increased length of hospital stay
increased morbidity and mortality
5 causes of sciatic nerve injury in THR?
- compression (most common) due to
- hematoma
- retraction
- tight bandages
- direct trauma
- heat from polymethylmethacralate polymerization
- stretch
- unknown (40%)
Ficat Classification of femoral head AVN
I: normal
II: sclerotic or cystic lesions
IIa: no crescent sign
IIb: subchondral collapse (crescent sign) without flatterning of femoral head
III: flattening of femoral head
IV: OA with decreased joint space with articular collapse
*Note: some use the Steinberg classification (see picture), which is a modification of Ficat
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3 signs of prosthetic infection on radiographs.
- periosteal reaction
- scattered patches of osteolysis
- generalized bone resorption without implant wear
How do you deal with MCL injury intra-operatively?
MCL transection/deficiency
- suture repair or suture anchor reattachment, use of either CR or PS implant, hinged knee brace for 6 weeks postoperatively
- use of unlinked constrained prosthesis
Both MCL and LCL
- revision to an hinged knee (linked constrained prosthesis)
How do you get an antibiotic spacer to elute more abx?
Increase porosity (hand mix instead of vacuum)
increase concentration of antibiotic
Increase surface area of cement (antibiotic beads)
4 variables that affect THA stability?
- component design (i.e. head size, skirts)
- component position (version/abduction)
- soft-tissue tensioning (offset)
- soft tissue function
Risk factor for sciatic nerve injury in THA
(4)
What percentage of patients have subclinical injury
What percentage of patients with a clinical nerve injury have persistent injury
Female
Revision surgery
DDH
70% have subclinical injury
80% of patients with nerve injury hae persistent neurologica dysfunction
In a loose femoral component (cemented > uncemented), how does the proximal femur remodel?
varus and retroversion
4 risks of iliopsoas impingement post THA
Retained cement
Malposition acetabular component
LLD
Excessive length of screws
After THA for CDH, patient has sciatic nerve palsy not responsive to conservative measures. What are 2 surgical options?
SUbtroch osteotomy
downsizing components
T/F? sterilization in argon/nitogen creates free radicals
True: free radicals are needed to create cross-linking
HOWEVER, sterilization in oxygen causes unacceptably high levels of free radicals, leading to a brittle PE with higher rates of failure
4 signs of a well fixed femoral component?
- spot-welds
- new endosteal bone that contacts porous surface of implant
- absence of radiolucent lines around porous portion of femoral stem
- proximal stress shielding in extensively-coated stems
- absence of stem subsidence on serial radiographs
3 contraindications to MoM implants
Pregnant women
Renal disease (metal ions excreted by kidneys)
Metal hypersensitivity due to metal ions
5 considerations for hemophiliac in arthroplasty
Replace factors to 100% preop
Abnormal morphology: valgus, flattened femorla head, acetabuluar dysplasia (like LCP)
Increased infection rates
Higher rate of failure
(no effect on HO)
What does stripe wear indicate?
Impingement and excursion that occurs during dislocation of component
stripe wear is cuased by edge loading and recurrent subluxation during gait
What is the general cutoff for metal ion levels that indicates further workup?
7ppb of cobalt or chromium
Contraindications to UKA
inflammatory arthritis
ACL deficiency
absolute contraindication for mobile-bearing UKA and lateral UKA
controversial for medial fixed-bearing
fixed varus deformity > 10 degrees
fixed valgus deformity >5 degrees
restricted motion
arc of motion
flexion contracture of > 5-10°
previous meniscectomy in other compartment
tricompartmental arthritis (diffuse or global pain)
younger high activity patients and heavy laborers
overweight patients (> 82 kg)
grade IV patellofemoral chondrosis (anterior knee pain)
AAOS classification for femoral bone loss
attached
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Bone marrow edema in femoral head AVN is predictive of what 2 things:
pain
eventual collapse
Outcomes (success rate) of 2 stage revision for infected arthroplasty?
70-90% in delayed (after 4-6 week abx) reimplantation
vs.
35% for early 2nd stage reimplantation
In setting of multiple revision TKA with multiple lateral scars. Where do you make your incision?
At the most lateral scar
Blood supply comes from medial so you want to preserve blood supply to lateral skin as much as possible
How does the Anderson Orthopedics Bone Loss Classification help decision making in revision TKR?
Type 1 – metaphyseal bone is intact and supportive of prosthesis – contained defects can be filled with graft or cement
Type 2 – Deficiency of metaphyseal bone compromises implant support – need to use a extended stem and combine this with either structural bone graft or a modular prosthesis that allows for augmentation
Type 3 – deficiency of metaphyseal region – Tumor prosthesis
Saggital balancing:
Flexion: Tight
Extension: Ok
What do you do?
Downsize femur
or
Slope tibia
Two features that antibiotic must have to be used in cement (ie for a spacer)
Heat stable
Water soluble
Decreasing offset does what to JRF in THA?
Increases it
b/c it weakens abductors
2 surgical treatments for Psoas impingment post-THR and what is indication for each?
1) Psoas release/tenotomy –> well positioned cup
2) Acetabular revision –> excessive anterior cup overhang
What is the minimum number of THA cases a surgeon must perform per year to have a base level of competence (decreased complications)
35
TT osteotomy techniqe (for TKR exposure)?
- 6-10 cm bone fragment cut from medial to lateral
- fixed with screws or wires
Contraindications to hip fusion?
active infection
severe limb-length discrepancy greater than 2.0 cm.
bilateral hip arthritis
adjacent joint degenerative changes
- lumbar spine
- contralateral hip
- ipsilateral knee
severe osteoporosis
degenerative changes in lumbar spine
contralateral THA
increased failure rate (40%) in THA when there is a contralateral hip arthrodesis
Treatment of acetabular bone loss by poprovsky grade?
- Type 1: Minimal deformity, intact rim
- Type 2A: Superior bone lysis with intact superior rim
- Type 2B: Absent superior rim, superolateral migration
- Type 2C: Localized destruction of medial wall
- Type 3A: Significant bone loss, superolateral cup migration
- Type 3B: Significant bone loss, pelvic discontinuity
Sheth et al. reviewed acetabular bone loss in revision total hip arthroplasty. They state that Paprosky Type 1 and 2 defects can usually be managed with porous-coated hemisphere cup secured with screws. Type 3 defects require reconstruction cages to protect with cups and structural augments or custom triflange implants.
What are the 4 steps of osteolysis?
- particulate debris formation
- macrophage activated osteolysis
- prosthesis micromotion
- particulate debris dissemination
Name two types of surface wear and two types of fatigue wear.
Surface = adhesive or abrasive
Fatigue = delamination or pitting
What is the go -to osteotomy for a valgus knee?
Varus producing distal femoral osteotomy
Most accurate and precise way to measure polyethylene wear
radiostereometric analysis
What single test must you order before converting a hip fusion to a THR?
EMG to assess gluteus medius.
If non-functional then you need to use a constrained liner.
3 ways to decrease post-op pain in TKA?
Per-articular injection
Peripheral nerve blockage
Not using tourniquet
AAOS CPG 2015
5 risk factors for neurovascular injury in TKA
- severe valgus or flexion defromity
- pre-operative neuropathy
- tourniquet longer than 120 min
- post op hematoma
- use of epidural anesthesia
Most important type of wear in the osteolytic process?
adhesive wear
PE sticks to prosthesis and debris gets pulled off
Why is it a bad idea to use posterior referencing in valgus knee?
Hypoplastic lateral condyle will lead to increased IR of the femoral component if unrecognized
What two things happen (biologically) with a chronic (>4 week) infection that necessitates explant instead of just I&D with a poly exchange?
bacteria forms a biofilm
bacteria invades bone-implant interface
5 Risk factors for developing motor nerve palsies post THA:
developmental dysplasia of the hip
revision surgery
female gender
limb lengthening
posttraumatic arthritis
surgeon self-rated procedure as difficult
Uncemented components
Other than instability, what is an important risk of valgus contracture release in TKR?
Peroneal nerve injury
Three technical methods to avoid wound complication in revision TKA
- Use most lateral incision
- dont cross incisions at angles less than 6o degrees
- 5-6 cm skin bridges
Name 4 options for extensor mechanism repair post rupture post TKA
Priamry repair
Autograft/Allograft reconstruction
Synthetic material
Gastrocs rotation flap
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Optimal porosity in biologic fixation:
50%
rule of 50’s
- pore size 50-300um
preferably 50-150um
porosity of 40-50%
gaps <50um
micromotion <150um
What is a Kerboul angle and what does it predict?
Combination of angles of involved areas of AVN on AP and Lateral xray. Higher the number higher the chance for progression.
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Patient with PS knee suffers acute pain and inability to move knee. Diagnosis and management?
Cam jump
Reduce using anterior drawer maneuver
What are the MSIS criteria for periprosthetic Joint Infection
- There is a sinus tract communicating with the prosthesis; or
- A pathogen is isolated by culture from at least two separate tissue or fluid samples obtained from the affected prosthetic joint; or
- Four of the following six criteria exist:
Elevated serum erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) concentration,
Elevated synovial leukocyte count,
Elevated synovial neutrophil percentage (PMN%),
Presence of purulence in the affected joint,
Isolation of a microorganism in one culture of periprosthetic tissue or fluid, or
Greater than five neutrophils per high-power field in five high-power fields observed from histologic analysis of periprosthetic tissue at ×400 magnification.
When do you treat post-operative LLD?
Wait 6 months for soft tissue tension to settle.
Should you routinely used navigated or patient specific TKA?
No
strong evidence against routine use
no difference in outcomes vs. conventional
AAOS CGP 2015
Use of a closed suction drain (hemavac, JP etc) post TKA gives a risk of what?
Increased risk of transfusion
Post-TKA - when should you start PT?
POD 0 - same day of surgery
Leads to better outcomes
AAOS CPG 2015
PAO - why can patient weight bear right away?
Posterior column remains intact
Unresurfaced patella vs. resurfaced patella in TKA will have: (2)
Higher risk of anterior knee pain
Higher risk of secondary resurfacing
What amount of femoral lengthening leads to increased rates of sciatic nerve palsy?
4 cm
Optimal position of hip fusion?
- 20-35° of flexion
- 0°-5° adduction
- 5-10° external rotation
In a simplified acetabular bone loss classification, what amount of bone loss suggests an incompetent vs. compentent rim?
>2/3 of rim remaining is competent
During TKA, implants are perfect but patella still maltracks. What is your first move?
DEFLATE THE TOURNIQUET
Three ways to change offset through femoral component selection.
- choosing a stem with more or less offset
- choosing a stem with a different neck-shaft angle
- modifying the length of the femoral neck
3 stages of the TKA Su classification of periprosthetic femoral fractures
I: fracture proximal to femoral component
II: # originates at proximal aspect of femoral component and extends proximally
III: any part of # line distal to upper edge of anterior flange of femoral component
Location of popliteal artery in relation to tibial plateau in flexion/extension
Extension: 1cm posterior
Flexion: 2cm posterior
5 contraindications to knee fusion.
- active infection
- bilateral knee arthrodesis
- contralateral leg amputation
- significant bone loss
- ipsilateral hip or ankle DJD
Complication of free-fibular transfer resulting in leg pain?
Tibial stress fracture
What is lambda in terms of arthroplasty?
Defines lubrication of MoM components
Lambda ratio = thickness of fluid film to the composite root mean square of surface roughness
- severe mixed lubrication
- Abrasive wear occurs via direct contact of the two bearing surface
>3:
- fluid film lubrication is sufficient to substantially reduce effect of load and minimze friction and wear
Name the nerve at risk with each hip portal:
a) anterior
b) Anterolateral
c) Posterolateral
a) LCFN
b) SGN
c) sciatic
5 types of wear
Adhesive:
- most important
- PE sticks to prosthesis and gets pulled off
Abrasive:
- cheese greater effect
3rd body
volumetric:
- main determinant of # of particles created
Linear
2 Complications specific to UKA
Tibial stress fracture (under baseplate)
tibial component collapse
(tibial side gets messed up)
What is the most commonly injured division of the sciatic nerve in THA?
peroneal division of sciatic
What type of antibiotic spacer elutes more antibiotics?
Static
Although eradication rates for mobile vs. static are the same!
Describe the Poprovsky acetabular bone loss classification.
Type I
Minimal deformity, intact rim
Type IIA
Superior bone lysis with intact superior rim
Type IIB
Absent superior rim, superolateral migration
Type IIC
Localized destruction of medial wall
Type IIIA
Bone loss from 10am-2pm around rim, superolateral cup migration
Type IIIB
Bone loss from 9am-5pm around rim, superomedial cup migration
Name 6 risk factors for peroneal nerve palsy post THA
Hip dysplasia
posterior approach
extreme lengthening
post-traumatic arthritis
uncemented femoral component
surgeon self-rating the surgery as difficult
Risk factors for periprosthetic fracture
osteolysis and loosening
trauma
age
gender
osteoporosis
index diagnosis
revision surgery
technique
type of implant used
(JAAOS 2014 - periprosthetic fractures)
You do a cup/cage for pelvic discontinuity. You find the hip to be unstable and don’t want to revise the femoral component.
What is an option to decrease instability?
Trochanteric advancement.
DO NOT use a constrained liner. It puts too much strain on the acetabular revision and it will fail. You can use a constrained liner if boney ingrowth has already occured.
4 Options for treating Paprosky 4 femoral bone loss
Incompetent isthmus
Allograft prosthetic composite
Long cemented stem
Impaction grafting + long cemented stem
Modular oncology components (femoral replacement)
Allogenic Transfusion triggers in TKA (JAAOS 2014)
DO NOT transfuse if >8g/dL
Absolutely transfuse if
Beween 6-8g/dL, depends on symptoms
This corresponds with the American Association of Blood Banks CPG that has a trigger of 8g/dL
Paprosky 1 femoral bone loss.
Outcomes of revision with primary, monobloc stems.
What should you do?
Poor: revision rates of 20% at 8 years
Use SROM instead. Revision rate of 1.5% at 7 years.
JAAOS 2013 (Paprosky - Femoral bone loss)
They say you can use monobloc stems in paprosky 1 but many have reported poor results and have moved towards distally fitted stems
Position of knee fusion if pre-existing LLD of > 2 cm?
Full extension because leg will be able to clear the ground during gait.
3 Methods to mobilize extensor mechanism for better exposure in revision TKR
- Lateral release
- Remove retro-patellar adhesions
- Subperiosteal dissection of superomedial tibia
What’s the issue with arthrocentesis for culture in periprosthetic joint infection?
Low sensitivity (28%)
Therefore careful how you use it
Same with gram stain
Risk factor for nonunion in ORIF of periprosthetic TKA fracutre of distal femur
Extensile lateral approach (vs. submuscular approach)
Use submuscular (MIPO)
What is the important structure at risk during a lateral retinacular release?
Superior geniculate artery
Can lead to extensor mechanism rupture or patellar fracture
5 complications to using constrained liner
Acetabular loosening
dissociation of the constrained liner from the shell
material fatigue
disengagement of the constraining ring
excessive wear
Three patient facors necessary for PAO?
- symptomatic dysplasia in an adolescent or young adult
- concentrically reduced hip
- mild-to-moderate arthritis
Lowest WBC & PMN from prosthetic joint apsirate that indicates infection?
WBC: >1100 cells/mm2
PMN: >64%
Both above: PPV 98.6%
Both below: NPV 98.2%
(Ghanem & Parvizi JBJS 2008)
TKA: Outcomes of All cemented vs. All uncemented
Same
AAOS CPG 2015
Two bail out options for repeat total hip dislocators once revision options exhausted?
Convert to hemi with large head
Resection arhtroplasty
What is the success rate of I and D + liner exchange for acute infection?
50-55%
Describe the Hartofilikadis classification.
Hartofilakidis Classification
Dysplasia (Type A)
Femoral head within acetabulum despite some subluxation. Segmental deficiency of the superior wall. Inadequate true acetabulum depth.
Low dislocation (Type B)
Femoral head creates a false acetabulum superior to the true acetabulum. There is complete absence of the superior wall. Inadequate depth of the true acetabulum.
High dislocation (Type C)
Femoral head is completely uncovered by the true acetabulum and has migrated superiorly and posteriorly. There is a complete deficiency of the acetabulum and excessive anteversion of the true acetabulum.
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
Acupuncture
STRONG evidence AGAINST
6 factors that influence success of revision TKR (think local factors)
(pre-op factors)
- Pre-surgical diagnosis and extent of reconstruction required
- ROM
- extensor mechanism function
- collateral ligament sufficiency
- Quality of skin and soft tissues
- remaining bone stock
Name 5 complications unique to THA
Sciatic nerve injury
HO
Osteolysis
Pseudotumour
squeaking
Dislocation
LLD
Iliopsoas tendon impingement
What are the driving recomendations post TKR?
- 4 weeks after a right total knee
- less than 4 weeks after a left total knee
Medial compartment OA. Outcomes of valgus HTO vs. Uni knee?
No difference
Moderate evidence
AAOS CPG 2015
What is the biggest risk for requiring postop blood transfusion post THA?
Low Pre-ob Hb
Saggital balancing:
Flexion: Good
Extension: Loose
What do you do?
Augment femur
or
Downsize femur + thicker poly
AVN hip: what factor determines whether you can do hip preservation vs. arthroplasty?
Kerboul angle
Kerboul angle >200 = arthroplasty
How does CPM effect outcomes following primary TKA?
Continuous passive motion (CPM) devices have not demonstrated superior clinical outcomes in multiple level 1 studies.
5 Risks of HO post THA
Prolonged surgical time
Hypertrophic subtype of OA
Handling soft tissues during surgery
Previous HO
DISH
Paget’s
Ankylosing Sponlylitis
Complications with TJA in hemophiliacs
Increased infection
increased risk of hematoma
Inreased stiffness/arthrofibrosis (not instability)
In what position should you close the knee after TKA?
Flexion, to avoid overtightening the extensor mechanism that leads to stiffness
6 risk factors for intra-operative acetabular fracture during THR?
- underreaming >2mm
- elliptical modular cups
- osteoporosis
- cementless acetabular components
- dysplasia
- radiation
5 things that maximize biologic fixation in arthroplasty
Rule of 50’s
- pore size 50-300um (preferably 50-150um)
- porosity of 40-50%
- gaps 50um
- micromotion 150um
- Maximal contact with bone
highyl cross-linked UHMPE has lower rates of what kinds of wear?
Adhesive and abrasive wear
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
Weight Loss
MODERATE evidence FOR
Saggital balancing:
Flexion: Tight
Extension: Tight
What do you do?
Thinner poly (min is 6 mm)
or
Resect tibia
What is the recommended femoral, acetabular and combined version in THA
Femoral: 10-15 degrees anteverted
Acetabular: 5-25 degrees anteverted
Combined: 37 degrees anteverted
2 options for treating Paprosky 3B femoral bone loss
Modular tapered stem with antirotational splines (Wagner style) - preferred
Impaction grafting + cemented stem
Cavitary defects in TKA. What do you use to fill a defect 1cm?
>1cm: augment or structural bone allograft
What differentiates osteonecrosis from transient osteoporosis on MRI?
Presence of a double density sign
Where is the peroneal nerve in relation to the lateral capsule
What do you have to do in TKA to protect it?
When doing a lateral capsular release, make sure you stay on bone (tibia) and use cautery
Describe the Paprovsky femoral bone loss classification.
Paprosky Classification of Femoral Bone Loss
Type I
Minimal metaphyseal bone loss
Type II
Extensive metaphyseal bone loss with intact diaphysis
Type IIIa
Extensive metadiaphyseal bone loss, minimum of 4 cm of intact cortical bone in the diaphysis
Type IIIb
Extensive metadiaphyseal bone loss, less than 4 cm of intact cortical bone in the diaphysis
Type IV
Extensive metadiaphyseal bone loss and a nonsupportive diaphysis
Contrast 1st to 3rd generation cementing techniques.
1st generation
- hand-mixed cement
- finger packed cement
- no canal preparation or cement restrictor
2nd generation
- cement restrictor placement
- cement gun
- femoral canal preparation
- brush and dry
3rd generation
- vacuum-mixing to reduce cement porosity
- cement pressurization
- femoral canal preparation
- pulsatile lavage
What is an advantage and disadvantage of zirconia compared to alumnia for bearing surfaces?
- Zirconia is tougher and less prone to fracture
- Zirconia can undergo phase transformation of tetragonal to monoclinic crystals that makes the surface rough and leads to wear.
What do spot welds mean for biologic fixation?
A well fixed component
represents new endosteal bone that contacts porous surface of implant
Contra-indications to using subvastus type incisions for TKR?
- ROM
- obese patient
- hypertrophic arthritis
- previous HTO
- Previous arthrotomy
- Revision TKR
How do you employ radiation to reduce HO formation?
600-800 cGy (6Gy) administered ideally within 24-48 hours following procedure
Describe the ratio for mixing antibiotic cement for vano and tobra.
In a 40 g bag of cement:
3 g of vanco
4 g of tobra (gent may be substituted for tobra)
What is the most common complication after isolated PE liner exchange in THA?
Dislocation
AAOS classification for acetabulr bone loss
see image
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What cytokine released by macrophages activates RankL during the osteolysis process?
TNF-Alpha
4 ways to treat patella baja in TKA
Superior placement of patellar component with resection of inferior pole
Lower joint line
Tibial tubercle transfer to cephalad position
Patellectomy
Saggital balancing:
Flexion: Ok
Extension: Tight
What do you do?
Resect femur
or
Release posterior capsule
Risks for early failure of HTO?
Which is most important?
Delayed or nonunion - most important
Presence of tibial lateral thrust (b/c lax LCL)
Age >50
BMI >25
Insufficient valgus correction
Pre-op flexion
Previous arthroscopic debridement
Treatment of a) proximal wound necrosis and b) distal wound necrosis with TKR?
a) local wound care and skin graft
b) Muscle flap coverage to protect extensor mechanism
What is the difference between Tc and In bone scans?
Tc-99m (technetium) detects inflammation and In-111 (indium) detects leukocytes
Define q angle
Angle between:
ASIS and center of patella (pull of extensor mech)
Center of patella and tibial tubercle (long axis of patellar lig)
Normal is 11 ± 7 deg
Remember this picture to figure out what causes patella instability
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Contrast the femur and tibia cuts made in classic versus anatomic cuts for TKR
Classic technique – 5-6 degree valgus femoral cut and neutral tibia cut
Anatomic technique – 9 degree valgus femur and 3 degree varus tibia
Describe the 3 types of ideal candidates for hip resurfacing according to Matta
- patients with proximal femoral deformity making total hip arthroplasty difficult
- patients with high risk of sepsis due to prior infection or immunosuppression
- patients with a neuromuscular diagnosis
What percentage of patients recover full strength after a sciatic nerve palsy in THA?
Only 35-40%
AVN of one hip, what must you investigate for?
AVN of contralateral hip
Bilateral disease 80% of the time
±multifocal disease (3%)
5 complications of knee osteotomy.
- Compartment syndrome
- Non or mal union
- Over or under correction
- Peroneal nerve injury
- Patella baja
Order of release for varus deformity in coronal plane balancing
- osteophytes, meniscus & its capsular ttachments
- deep MCL & capsule
- posteromedial corner
* semimembranosus & capsule - Superficial MCL
- do not fully release. Perform either
- subperiosteal elevation or
- differential release: posterior oblique if tight in extension, anterior portion if tight in flexion
- PCL
Equipment on hand for a femoral stem removal?
To facilitate stem removal, the following instruments should be on hand:
- manufacturer-specific explant tools
- flexible osteotomes
- trephines
- high-speed burrs (eg, pencil tip, carbide tip, metal cutting wheel)
- ultrasonic cement removal instruments
- universal extraction tools that allow attachment to the stem or taper
3 patient contraindications for MoM bearings?
- pregnant women
- renal disease
- metal hypersensitivity due to metal ions
What is the outcome of cryotherapy and CPM machines post TKA?
No improvement in outcome for either
What prevents collapse in hip AVN?
bisphosphonates
(more than core decompression)
Hip and knee Arthroplasty:
Low virulence infection in immunocompromised patient, within minimal increase in ESR, CRP. What type of infection should you suspect?
Fungal
Candida most common
5 risk factors for nerve injury in TKR?
- preoperative valgus and/or flexion deformity
- tourniquet time > 120 min
- postoperative use of epidural analgesia
- aberrant retractor placement
- preoperative diagnosis of neuropathy (centrally or peripherally)
Downside of using tourniquet in TKA?
Does it affect outcome
Incrased post-op pain
No effect on outcome
AAOS CPG 2015
List 2 absolute and 3 relative contraindications for hip resurfacing
absolute
- bone stock deficiency of the femoral head or neck (e.g., cystic degeneration of the femoral head)
- abnormal acetabular anatomy (small)
relative
- coxa vara (increased risk for neck fractures)
- significant leg length discrepancies (resurfacing does not allow for leg length corrections)
- female gender (controversial)
5 causes of late instability of THR?
- polyethylene wear
- component malpositioning or loosening
- trauma
- infection
- deterioration in neurological status of the patient
What is the role or arthroscopy and lavage in knee OA?
No role
AAOS CPG
5 indications for PS TKA
Indicated whenever there is risk of AP laxity
If also valgus/varus laxity - consider constrained
Inflammatory arthritis
PCL deficiency/Functionally absent PCL
Previous patellectomy
Varus deformity >10 degrees
Valgus deformity >15 degrees
Order of release in Varus TKA deformity
Osteophytes, meniscus and capsular attachments
Deep MCL
Capsule
Posteromedial corner (semimembranosus & capsule)
Superficial MCL
PCL
*My CORR Recon instructor said it doesn’t matter your order, as long as have you have one and it makes sense (ie don’t start with PCL)
** MY CORR Recon instructor could beat up YOUR CORR Recon instructor
How will leg length be affected by placing the femoral center of rotation above/below the acetabular center of rotation?
Femoral above acetabular:
- increased leg length
Femoral below acetabular:
- decrease leg length
What is the primary indication for conversion to a constrained acetabular component?
recurrent instability with a well positioned acetabular component due to soft tissue deficiency or dysfunction
4 risk factors for wear in a tibial baseplate sterilized in air?
- Increasing shelf age
- younger age
- male gender
- rough tibial baseplate
5 ways to increase offset in THA
increasing length of femoral neck
decreasing neck-shaft angle
medializing the femoral neck while increasing femoral neck length
trochanteric advancement
alteration of the acetabular liner (lateralized liner)
Describe Tonnis arthritis grade
0: no signs of OA
1:
sclerosis of the joint
minimal joint space narrowing & osteophyte formation
2:
small cysts in the femoral head or acetabulum
Moderate joint space narrowing
3:
Advanced arthritis
large cysts in femoral head/acetabulum
Joint space obliteration and severe deformity of the femoral head
2 methods of polyethylene production and which is better?
1) Compression moulding - better
2) Machining - Inferior because machining shear forces lead to cracking and delamination
grit blasted surfaces allow for what kind of biologic fixation?
ongrowth
Imaging to assess for pseudotumor?
MRI with metal subtraction.
A 58-year-old man has significant pain and stiffness after undergoing right total knee arthoplasty 6 months ago. ESR is 45mm/hr (normal 0-20) and a CRP is 13.5 mg/l(normal
Repeat aspiration
Best step in equivocal aspirate is re-aspiration
In general, how do posteromedial knee structures affect flexion vs. extension gaps in TKA?
Posteromedial knee structures affect extension fap (ie semimembranosus)
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Preferred approach to hip arthrodesis?
Lateral approach with trochanteric osteotomy
or
Anterior approach
Must preserve abductors
4 advantages of articulating antibiotic spacer
Decreased reimplantation exposure time
Better maintenance of joint space and motion
Decreased quad shortening
Better patient satisfaction
4 Technical methods to avoid patellar mal-tracking
- ER femoral component 3 degrees
- Lateralize the femoral component
- ER tibial component
- Patella button on superomedial patella
Comparison of Warfarin, LMWH, Rivaroxaban in VTE prophylaxis (general)
Rivaroxaban > LMWH > Warfarin at preventing clots
Rivaroxaban > LMWH > Warfarin in bleeding risk
Position of knee fusion?
5-7 valgus
15 flexion
Classification of patellar periprosthetic fractures
Goldberg
Type I: not involving implant/cement interface of quads mechanism
Type II: involving implant/cement interface or quads
Type III
A: inferior pole fracture with patellar ligament rupture
B: Inferior pole fracture without patellar ligament rupture
Type IV: all types of fracture dislocations
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Which classification is this?
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AAOS Classification of Acetabular Bone Loss
List 4 options to deal with patella Baja during TKR.
- Place patellar button superior and trim inferior osteophytes (mild baja)
- Lower joint line (moderate)
- Tibial tubercle cephalad transfer (moderate)
- Patellectomy (severe)
3 methods of increasing exposure after medial parapatellar approach and mobilization of extensor mechanism.
Rectus snip
Vy turndown
TT osteotomy
Asymptomatic AVN of hip ID’ed on MRI, what percentage of patients will go on to collapse? What if they have Sickle cell?
33%
75% in patients with sickle cell
5 Risks of intraoperative periprosthetic femur fracture
Female
Technical errors
Cementless implants
osteoporosis
Revision
Cementless press-fit technique
Compromised bone stock
Impaction grafting technique
- Prophylactive cerclage wires and cortical onlay strut allografts are recommended to help reduce the risk
Mimimally invasive technique
4 Risk factors for HO in THR?
- prolonged surgical time
- excessive soft tissue handling during procedure
- hypertrophic osteoarthritis
- male gender
What 5 technical factors will lead to patellar maltracking in TKA?
IR of femoral component
medialization of femoral component
IR of tibial component
Medialization of the tibial component
Placing patellar component on the lateral side of patella
in MoM components, what causes seizing?
No enough clearance (difference in diameter between acetabular and femoral components)
Clearance 100-200um maximizes fluid thickness
Too much clearance: wear as fluid is allowed to leak out between components
Too little clearance: not enough fluid in between components
Clamping/equatorial seizing
Cement mantle how thick leads to increased risk of fracture?
How are metal ions excreted?
Renal
Risk of patellar prosthesis failure
- Metal backed components
- poor ingrowth
- peg failure
- dislocation of poly
- component fracture
• poor surgical technique
- asymmetric resection (not achieving equal facet thickness)
- excessive patellar resection (not maintaining native patellar height)
- overstuffing PF joint
- not maintaining vascular supply
- poor patellofemoral tracking
Lab test with highest correlation to periprosthetic infection?
IL-6
Kerboul classification of femoral head AVN
Gives cross sectional area of AVN as a combined angle
190-240o: 50% chance of collapse
>240o: 100% risk of collapse
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Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
HTO
LIMITED evidence FOR
Contrast the timing of post-operative femur periprosthetic fractures for cemented versus cementless?
Cemented = usually > 5 years out, occurs at the tip
Cementless = Usually within first 6 months due to stress riser created during broaching. Tapered stems fracture in metaphysis, extensive coated stems fracture more distally.
Name risk factors for periprosthetic infection
There are 17
(THINK: ADRIAN BLOWS MONKEYs)
Preoperative
- Malnutrition
- DM
- Obesity (BMI > 40kg/m2)
- Male
- Post-traumatic arthritis
- inflammatory arthritis
- Colonization with MRSA
Intraoperative
- Inadequate Skin prep
- Surgical gowns and gloves (no difference between space-suits, but both and gloves are highly contaminated)
- Regular cement
- OR configuration/traffic
- Wound closure
- Longer OR time
Postop
- Retention of foley > 1 day
- Blood transfusions
- Prolonged wound Drainage
- Dental Procedures
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What is the best predictor of ambulatory status following conversion of hip fusion to THR?
Gluteus medius function.
5 techniques for acetabular revision
- Hemispherical cup –
- need 50% bone stock, use 2 mm larger than last reamer, augment with screws
- Jumbo cup – usually 6-10 mm larger than previous cup
- High hip center
- Impaction grafting with a cemented cup
- Structural allograft
- Cup cage – no posterior wall, significant loss of superior bone, discontinuity.
- Tantalum cup with augments
6 risk factors for femoral neck fracture following hip resurfacing.
- notching of the femoral neck
- osteoporotic bone
- large areas of preexisting osteonecrosis
- femoral neck impingement (from malaligned acetabular component)
- female sex
- varus positioning of femoral component
3 factors that affect risk of AVN after hip dislocation
Amount of initial displacement
reduction
decompression of hematoma (maybe)
Most common complication after revision THA in the setting of pelvic discontinuity?
dislocation
2 forms of prophylaxis in HO
NSAIDs
Radiation therapy
700cGy (7 Gy) (THA) 24-48hrs post op
How do you re-establish the correct joint line in revision TKR?
Revise tibial side first.
Tibial joint line should be 1.5 to 2 cm above head of fibula.
Can also compare to other knee with xray.
3 major common complications of PAO?
Anterior overcorrrection
NV injury
Intra-articular fracture
What is the most common reason for THA revision?
Instability
What does heating do in the process of making polyethylene?
Decreases free radicals
DORR classification
Measurement of IM canal width at the LT and width of IM canal 10cm below
Measurement at diaphysis divided by measurement at LT
Dorr A:
- Ratio
- Cortices seen on both AP & Lateral
- Amenable to uncemented
Dorr B:
- Ratio 0.5 - 0.75
- Thinning of posterior cortex on lateral
- Still ok for uncemented
Dorr C:
- Ratio >0.75
- Thinning on both views
- Stovepipe femur
- Use cemented
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What is a differential release of the superficial MCL?
Release in 2 parts:
Posterior oblique: tight in extension, so release if tight in extension
ANterior portion: release if tight in flexion
Contraindication to using extensively porous coated stem for revision of a type 3 femur?
IIIB defects with canals >19 mm in diameter
Two technical factors that increase MoM wear rates?
Abduction > 55 and smaller head size
Define Contact pitch to rim distance
in MoM components
Distance between point of application of the JRF and the rim of the acetabular component in standing position
Inverse relationship between CPR and wear
What is the first step if the patella lateralizes during ROM with trial implants in place?
Deflate tourniquet and try again.
Name two types of antibiotic spacers and a benefit/drawback for each.
Dynamic - Better patient function and satisfaction, however less effective at eluting antibiotics.
Static - No ROM and poorer satisfaction, much better abx elution.
*No difference in eradication rates between mobile/static spacers
7 steps to optimize cement fixation
limited porosity of cement
- leads to reduced stress points in cement
cement mantle > 2mm
- increased risk of mantle fractures if
stiff femoral stem
- flexible stems place stress on cement mantle
stem centralization
- avoid malpositioning of stem to decrease stress on cement mantle
smooth femoral stem
- sharp edges produce sites of stress concentration
absence of mantle defects
- defined as any area where the prosthesis touches cortical bone with no cement between
- creates an area of higher concentrated stress and is associated with higher loosening rates
proper component positioning within femoral canal
- varus or valgus stem positioning increases stress on cement mantle
Contra-indication to using a extensively porous coated long stem postethis for Pop Type IIIb defects?
Canal diameter greater than 19 mm.
What is run-in wear?
Increased wear for 1st million cycles (~1 year) in MoM components
A steady state of wear follows
Valgus Deformity order of release in coronal plane balancing
- osteophytes
- lateral capsule
- ITB (if tight in extension)
* perform Z-plasty or release off Gerdy’s tubercle - Popliteus
- LCL
- some release LCL first if tight in both flexion and extnesion
- Cannot do full release or will get varus laxity- pie crust.
wear rate of non and highly cross-linked UHMPE
non-crosslinked UHMPE: 0.1-0.2mm/yr
crosslinked: 0.003mm/yr
Smaller particles and more resistant (but worse mechanical properties)
Stratgies for minimizing blood loss in TKA
JAAOS 2014
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2 necessary pieces of equipment for removing a well fixed cup
flexible osteotomes and size specific removal tools
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
lateral wedge insoles
Moderate Evidence Against
AAOS, for or against:
Viscoelastic supplementation
glucosamine & chondroitin
acupuncture
lateral wedge insoles
Needle lavage
All against
Post op TKA
Now stiff
9 causes
- Poor compliance with postoperative rehabilitation
- Postoperative complication (wound dehiscence, DVT, CRPS)
- Overstuffing of the patello-femoral joint
- Oversized components (femur)
- Failure to restore native tibial slope (insufficient tibial posterior slope)
- Incomplete osteophyte resection
- Mismatch of flexion and extension gaps (inappropriate balancing (PCL too tight)
- Component Malposition
- Elevation of the joint line
Technical Risk factors for TKA periprosthetic femoral fractures (3)
- anterior femoral notching (debatable)
- mismatch of elastic modulus between metal implant and femoral cortex
- rotationally strained components
Which femoral condyle is bigger? What does this produce in terms of kinematics?
Lateral is larger
Creates medial pivot point during flexion
Give the paprosky classification for acetabular bone loss
see image
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What is reccomended combined anteversion?
37 degrees
Approach to extensor disruption in TKR?
- Partial quads tear = 6 weeks zimmer
- Complete quads tear or partial patellar avulsion from TT = Direct repair
- Complete patellar tear with good tissues = primary repair with allograft
- Complete tear with poor tissues = extensor mechanism allograft (this sounds crazy)
Post posterior approach THA in an ankylosing spondylitis patient, what are they at risk of?
Anterior dislocation
Due to pre-existing lumbo-pelvic angulation
3 stages of the TKA Lewis and Rorabeck classification of periprosthetic femoral fractures
I: Non-displaced; component intact
II: Displaced; component intact
III: Displaced; component loose or failing
Neuropathic joint: what kind of TKA shoud you use?
Hinged
3 prognostic indicators for collapse in hip AVN (radiographic)
Kerboul angle >190
- 190 - 240: 50%
- >240: 100%
AVN of > 2/3 of the weight bearing surface of femoral head
Medium to large lesions (>30% in Steinberg classification)
- 30-50%: 46% collapse
- >50%: 85% collapse
Bone marrow edema in proximal femur
JAAOS 2014
What is an advantage and disadvantage of poly insert/metal tray compared to all poly tibias?
1) Intra-operative modularity is the advantage
2) Drawbacks are backside wear and expense
Order of release in valgus TKA
Osteophytes
capsule
IT Band
Popliteus
LCL
*May release LCL first if tight in both flexion & extension
*Consider constrained prosthesis if you release LCL
In an asymptomatic patient with a recalled MoM prosthesis, should you perform revision surgery?
No
Risk of revision not justified if they are asymptomatic (JAAOS 2015)
3 advantages and disadvantages of antibiotic spacers?
Advantages:
- reduce dead space
- provide stability
- deliver high dose antibiotics
Disadvantages:
- local/systemic allergic reactions
- antibiotic resistance
- can only use heat stable antibiotics
What is the standard magnification on an xray?
20%
Disadvantages of HCLPE:
Decreased toughness
Decreased ductility
Decreased fatigue strength
Decreaed ultimate tensile strength
Increased cost
How much knee flexion do you need for:
a) Swing phase of gait
b) ADLs
c) Getting out of chair
a) 65 degrees
b) 90 degrees
c) 105 degrees
46 yo who had Perthes at age 6, treated with abduction bracing, now has hip pain, failed all non-op measures, flat mushroom shaped femoral head, well contained. Best treatment
valgus extension femoral osteotomy
b/c well contained, valgus will:
- Corrects LLD
- Improves ROM (especially abduction)
Indications
late or salvage procedure, hinge abduction, medial dye pool
clinical presentation of aseptic acetabular and femoral loosening
Acetabular: buttock/groin pain
Femoral: thigh pain, startup pain
Describe typical findings of osteonecrosis on MRI.
double density appearance
T1: dark (low intensity band)
T2: focal brightness (marrow edema)
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What three factors are important when deciding between hip preserving or arthroplasty options for hip AVN?
- Is etiology reversible (i.e. steroids)
- Stage of AVN (particularly is collapse present)
- Age of patient
5 risk factors for THA dislocation
Prior hip surgery: Greatest risk factor
Female sex
>70-80 years of age
Posterior surgial approach
- Repairing capsule and reconstructing ER brings dislocation rate close to anterior approach
Malpositioning of components
- Ideal positioning of acetabular component: 40 degrees abduction, 15 degrees anteversion
Spastic or neuromusular disease (Parkinsons’)
Drug or alcohol ause
Decreased offset (decreases tension and stability)
Decreased femoral head neck ratio
AVN of femoral head
Inflammatory arthritis
Fracture treated with THA
Optimal pore size in biologic fixation:
50-150um optimal
50-300um acceptable
rule of 50’s
pore size 50-300um
preferably 50-150um
porosity of 40-50%
gaps
micromotion
Name 2 non-operative management modalities of AVN femoral head:
Bisphosphonates
pre-collapse: will prevent collapse (in some studies)
Electromagnet stimulation
Shockwave therapy
Hyperbaric osygen
5 factors that lead to increased wear rates in THA?
- poly thickness
- malalignment of components
- patients
- men
- higher activity level
What is the most common complication after proximal tibial osteotomy?
Patella baja
Saggital balancing:
Flexion: Tight
Extension: Loose
What do you do?
Downsize femur, thicker poly
Can’t reduce a THR post implantation? Name some soft tissue releases that may help.
Adductor release.
Gluteal release.
Rectus release.
indications for PAO (5)
- Near congruent DDH deformity
- Young patient (
- No advanced OA
- Adequate motion
- Correctible deformity
Effects of an increased offset in THA (5)
increased soft-tissue tension
Decreased dislocation
decreased impingement/increased ROM
decreased joint reaction force
Decreased wear
3 variables effecting elution of antibiotics from cement.
- cement porosity
- surface area
- concentration of abx
5 Risks of Squeeking in THA
impingement
edge loading
component malposition
loss of fluid film lubrication
third body particles
thin, flexible (titanium) femoral stem
Two reasons to use a cemented acetabular cup
Poor bone stock
Irradiated bone
What are paprosky type 1-5 acetabular peri-prosthetic fractures? (Don’t worry about sub-types)
- intraoperative fracture - component insertion
- intraoperative fracture - component removal
- traumatic fracture
- spontaneous fracture
- pelvic discotinuity
Risk factors for periprosthetic fracture
poor bone quality due to
- age
- steroid use
- rheumatoid arthritis
- stress-shielding
mechanical stress-risers due to:
- screw holes
- local osteolysis
- stiffness
neurological disorders, including:
- epilepsy
- Parkinson’s disease
- cerebellar ataxia
- myasthenia gravis
- polio
- cerebral palsy
AVN vs. Post-traumatic arthritis.
Wich one is more likely to get nerve injury and which is more likely to get instability after THR?
AVN = Instability
Post-traumatic = Nerve Injury
3 Contraindications to Ganz PAO
- Significant anterior cartilage wear (will end up in WB zone)
- Combined Cam and Pincer
- Excessive posterior wall coverage (will lead to extension impingement)
6 causes of post-op foot drop in THA
Posterior retractor (retraction)
Increased leg length/traction (traction)
Laceration
Hematoma
Scarring/HO
Entrapment sutures
Anesthesia
Seroma
Heat form cement
Idiopathic
Patient with patellectomy. what kind of TKA does he need?
PS
T/F? oxidation of PE occurs regardless of sterilization procedure?
True
However some ways accelerate it (ie in oxygen)
How can you quantify bone turnover in the osteolysis process?
(A lab test)
N-telopeptide urine level
T/F? Sterilization in oxygen causes free radicals
True: free radicals are needed to create cross-linking
HOWEVER, sterilization in oxygen causes unacceptably high levels of free radicals, leading to a brittle PE with higher rates of failure
Best to sterilize in nitrogen or argon or vacuum. These create the right amount of free radicals to make a cross-linked, wear resistant PE
What kind of femoral stem (cemented vs. uncemented) should you use in revision THA?
UNcemented
cemented his lower success rates
Most common intraoperaitve fracture in TKA
meidal femoral condyle
Best test for periprosthetic infection?
PET scan
98% sensitive
98% specific
How much can you lengthen femur before sciatic nerve palsy sets in?
4cm
(or 20% length of limb)
What are anterior precautions?
avoid :
- bridging
- extension
- extreme external rotation
- adduction past body’s midline
Heat stable antibiotics (4):
- Tobramycin
- Vancomycin
- Gentamycin
- Amphotericin B
5 risk factors for post-operative periprosthetic supracondylar femur fractures.
- Rheumatoid arthritis
- Parkinson’s disease
- Chronic steroid therapy
- Osteopenia
- Female gender
Treatment options for TKA periprosthetic femoral #
Antegrade IM nail
Retrograde IM nail
ORIF with fixed angle device
Revision to long-stem prosthesis
Distal femoral replacement
Indication for flexion, IR proximal femoral osteotomy?
post- SCFE
What do you look for as a marker for increase bone turnover/osteolysis?
Urine N-telopeptide
Describe two abnormalities of the femoral head and acetabulum with adult hip dysplasia.
Femoral head:
- decreased sphericity
- decreased head:neck offset
Acetabulum
- increased retroversion (Crossover sign)
- acetabular protrusio
3 options for operative management of stiff TKA
MUA
Arthroscopic/open lysis of adhesions
Revision TKA
Who is at greatest risk for developing pelvic discontinuity following THA?
RA patients
7 intraoperative methods to prevent infection in arthroplasty
Perioperative adminstration of abx
shorter OR time
Appropriate skin preparation before surgical incision
Frequent glove changes
use of antibiotic-impregnated cement
Limiting operating room traffic
Wound closure with sutures or staples
Laminar flow rooms
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What patients are candidates for hip resurfacing with adult hip dysplasia?
Crowe 1-2
(also male, adequate femoral bone stock, ect)
What are posterior precautions?
avoid:
- flexion past 90 degrees
- extreme internal rotation
- adduction past body’s midline
5 factors leading to higher wear rates?
PE Thickness
malalignment of components
Patients
men
higher activity level
*femoral head size 22-46mm does NOT affect wear of UHMPE
Osteoarthritis of the Knee
AAOS Guidelines Level of Evidence for:
needle lavage
Moderate evidence AGAINST
MSIS criteria for periprosthetic joint infection:
Definitely present when:
- There is a sinus tract communicating with prosthesis
or
- A pathogen is isolated by culture from 2 separate tissue or fluid samples obtained from the affected joint
or
4 out of 6 of the following are present:
- increased ESR & CRP
- Increased synovial WBC
- Elevated percentage of PMNs
- Purulence in the affected joint
- Isolation of a pathogen in 1 culture of periprosthetic tissue or fluid
- >5 neutrophils/hpf at 400x magnification
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Position of hip fusion?
30-5-10
30 flexion
5 adduction
10 ER
When is urine/serum metal concentration highest after MoM THR?
12-24 months.
This is because MoM has an intitial period of increased wear during the first year called the “run in” phase.
Risk factors for extensor mechanism rupture after TKA
Systemic disease (RA)
revision surgery
previous patellar realignment surgery
previous HTO
5 risk factors to wound complications post TKA
Systemic factors:
- Diabetes
- Vascular disease
- RA
- Medications
- Tobacco
- Poor nutritional status
- Albumin
- Total lymphocyte count
- Perioperative anemia
- Obesity
Local factors
- Previous incision
- Skin bridges should be 5-6cm
- Avoid crossing previous skin incisions at acute angles
- Knee deformity
- Skin adhesions
- Poor local blood supply
Technique
- Large subcutaneous flaps
- Not preserving subcutaneous fat layer
Post-operative
- Hematoma
- Infection
3 indications for a cemented femoral component?
- Dorr C femur - Stovepipe
- Severe osteopenia (elderly patient) - cement peentrates well into osteopenic bone
- Irradiated bone - wont ingrow
Patient post-op arthroplasty (past the acute period) presenting with pain. What is your next step?
Rule out infection
Pain = suspect infection
PT only if purely mechanical symptoms
Name the main nerves to the lower extremity as they relate to the Psoas in the pelvis.
Lateral: (3)
- Iliohypogastric n
- Ilioinguinal n
- LFCN
Medial: (2)
- Obturator
- Lumbosacral trunk
Between psoas & iliacus (1)
- Femoral
Piercing then lying anterior to psoas (aka through) (1)
- Genitofemoral
Best option for dealing with a loose cemented cup?
Remove and revise to a cementless cup
Describe the Crowe classification.
Crowe Classification
Grade
Proximal displacement
Femoral head subluxation
I
Less than 10%
• Less than 50%
II
10-15%
• 50-75%
III
15-20%
• 75-100%
IV
Greater than 20%
• Greater than 100%
3 tricks for extensile exposure in TKA
Quadriceps snip
V-Y turndown
Tibial tubercle osteotomy
Name 3 ways to restore/modify offset
choosing a stem with more or less offset
choosing a stem with a different neck-shaft angle
modifying the length of the femoral neck
List 2nd/3rd generation cementing techniques (AKA the ones we use now)
2nd generation
- cement restrictor placement
- cement gun
- femoral canal preparation (brush and dry)
3rd generation
- vacuum-mixing to reduce cement porosity
- cement pressurization
- femoral canal preparation: pulsatile lavage
What are the mechanical factors of highly cross-linked UHMPE vs. conventional?
decreased toughness, ductility, tensile strength, and fatigue strength
It has better wear properties, but worse biomechanical properties
Give the Paprosky classification for femoral bone loss
see image
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What are the differences in functional outcomes between dynamic and static antibiotic spacers?
No difference in functional outcomes
Porous coated metallic surfaces allow for what kind of biologic fixation?
ingrowth
5 techniques to increase offset?
- increasing length of femoral neck
- decreasing neck-shaft angle
- medializing the femoral neck while increasing femoral neck length
- trochanteric advancement
- alteration of the acetabular liner (lateralized liner)
What is the role of MMPs?
- matrix metalloproteases
- proteolytic enzymes
- responsible for cartilage matrix digestion
Classification of tibial periprosthetic fracutre (TKA)
Felix & Associateds
Type I: fracture of tibial plateau
Type II: fracures adjacent to tibial stem
Type III: Fracture of tibial shaft, distal to component
Type IV: fracture of tibial tubercle
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3 alternatives to posterior referencing in valgus TKA?
anterior referencing
Whitesides line
transepicondylar axis
custom knee?
Navigation?
4 radiographic signs of well fixed femoral component (biologic fixation)
spot welds
absence of radiolucent lines around porous portion of stem
proximal stress sheilding in extensively coated stems
absence of stem subsidence on serial x-rays
When is it appropriate to perform an isolated popliteus release in TKA?
valgus & tight in flexion
Name a prosthetic option for each poprosky type of femoral deficiency in revision femur surgery. (give a safe answer for each)
- Metaphyseal porous coated
- Extensively porous coated cylindrical stem
3a. Extensively porous coated cylindrical stem
3b. Modular tapered stem (i.e. distal press fit) / Wagner - APC (allograft prosthetic composite) or tumor prosthesis
3 Indications for the use of a constrained acetabular component
1) recurrent dislocations due to unrepairable soft-tissue insufficiency from lack of abductor function or capsular attenuation
2) severe cognitive disorders
3) late dislocations with well positioned components.
in TKA, which is better, neuraxial or general anesthetic?
Neuraxial
Decreased overall complications
AAOS CPG 2015
5 indications and 3 contraindications to hip fusion.
- Indications
- High activity
- Severe pain
- Post traumatic or post infectious
- Normal adjacent joints
- Contra indications
- Abnormal adjacent joints
- Active infection
- LLD > 2 cm
What is the maximum depth of osteochondroplasty to limit risk of femoral neck fracture?
30% of diamter of femoral neck
Sensitivity & specificity of gram stain in diagnosing periprosthetic joint infections?
Sensitivity: 0-23%
Specificity: 100%
Sensitivity too low. DO NOT use alone
Options for Knee Fusion Fixation
- Wichita (hinged) nail
- Longe antegrade nail
- External Fixation
- unilateral external fixation
- Ilizarov
- Taylor Spatial Frame
- Plate Fixation
Indications for MUA in stiff TKA:
- Timing is controversial but definitely do NOT do MUA after 12 weeks
What is the role of hydroxyapatite (HA) in THR?
- osteoconductive agent used as an adjunct to porous-coated and grit blasted surfaces
- has shown shorter time to biologic fixation in animal models, but no advantage clinically in humans
What is the difference between resurfacing the patella or not resurfacing with respect to the following outcomes:
1) pain
2) function
3) re-operation rates
1) pain = No Difference
2) function = No Difference
3) re-operation rates = Higher with non-resurfaced
Name 2 surgical interventions for AVN femoral head for early (precollapse) disease
Core decompression
Non-vascularized bone grafting
Vascularized bone graft (not really done anymore)
What is the gold standard treatment for chronic periprosthetic infection?
2 stage revision
IV abx 4-6 weeks in between
wear rate of of MoM
2.5-5um per year
wear rate of of ceramic on ceramic and ceramic on PE
C on C: 0.5-2.5um per year (not mm)
C on PE: 0-150um per year
Saggital balancing:
Flexion: loose
Extension: loose
What do you do?
Thicker Poly
does femoral head size affect wear
Not for sizes beween 22-46mm in highly crosslinked UHMWPE
for the old non-crosslinked it does
What treatment is indicated for proximal versus distal skin necrosis following TKR?
1) Skin necrosis of the proximal wound including the area over the patella can be treated by local wound care and skin grafting
2) Skin necrosis over the tibial tubercle or patellar tendon requires muscle flap coverage to prevent extensor mechanism disruption and deep infection
What does patella baja cause?
Inability to fully flex knee
Due to mechanical block as patella impinges on tibia in extreme flexion
Patella descends during knee flexion. if it’s already low, then it will impinge on tibia prior to full flexion
what is the mechanism of osteolysis in implant wear?
RANKL mediated bone resorption (via osteoclasts)
2 ways to decrease blood loss in TKA as per AAOS CGP 2015?
Tranexemic acid
tourniquet
5 risks of periprosthetic joint infection:
Immune suppression
- Drugs: steroids, DMARDs
- Conditions: HIV
Perioperative surgical site infection
Poor wound healing
RA
Psoriasis
Diabetes
Smoking
Obesity
Table is for TKA specifically, JAAOS 2015
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what is the linear wear rate that is associated with osteolysis and subsequent component loosening?
>0.1mm/yr
What is your choice of knee prosthesis with moderate bone loss in the setting of neuropathic arthropathy?
VVC
(** Rotating hinge if MASSIVE bone loss)
List 3 nonoperative management modalities that has strong evidence for in knee OA
NSAIDs or tramadol (strong)
Combined supervised and self monitored home exercise program (strong)
weight loss program (moderate)
After how many months do the risks of MUA out weight the potential beenfits in a stiff TKR?
3 months
How far is the popliteal artery from the posterior tibial cortex at 90 degrees flexion?
9 mm
What is the current reccomendation for use of ABX cement in TKR?
- Reccomended for revisions
- No good evidence for primaries. Don’t use routinely because it compromises the strength and can lead to higher rates of asceptic loosening.
Main cause of metal hypersensitivity in arthroplasty
Nickel (it is found in Cobalt-chromium alloys)
What material of THA has the best wear characteristics but the worst biomechanical characteristics?
Ceramic
Two causes of CAM jump on PS knee and what is reduction maneouver?
- Hyperextension or loose flexion gap
- anterior drawer
6 (proposed) advantages of UKA over TKA?
- faster rehabilitation and quicker recovery
- less blood loss
- less morbidity
- less expensive
- preservation of normal kinematics
- theory is that retaining ACL, PCL and other compartments leads to more normal knee kinematics
- smaller incision
- less post-operative pain leading to shorter hospital stays
What is the most common problem in TKA?
Abnormal patellar tracking
Treatment algorithm for AVN femoral head
See image
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Outcomes for rectus snip comapred to standard medial parapatellar approach in revision TKA?
No difference
In what position do you perform your posterior release in TKA?
90 deg of knee flexion
to protect popliteal artery
Saggital balancing:
Flexion: Loose
Extension: Ok
What do you do?
Resect femur + thicker poly
or
Posterior releases + thicker poly
What is the recommended theta (abduction) angle in THA?
30-50 degrees
What is the normal relationship between the posterior condylar axis and the transepicondylar axis?
3 deg IR
in TKA, must make femoral cut in 3 deg ER to make it parallel to transepicondylar axis
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2 absolute and 3 relative contraindications for hip resurfacing?
Absolute:
Poor femoral neck bone stock
Abnormal acetabular anatomy
Relative:
Female
LLD
Coxa Vara
Describe the method for preventing non-union of TT osteotomy
Long osteotomy maintain attachment of anterior compartment muscles to the fragment.
Optimal gap space in biologic fixation
rule of 50’s
- pore size 50-300um
preferably 50-150um
porosity of 40-50%
gaps
micromotion
5 contraindications to constrained liners in THA
malposition
component loosening
insufficiency of bone
acute infection
skeletal immaturity
neurologic spasm
3 signs of well biologically fixed acetabular component
lack of migration of serial x-rays
lack of progressive radiolucent lines
intact acetabular screws
5 properties of antibiotics that can be used in cement:
Heat stable
water soluble
bactericidal
Targeted
Good elution properties
Non-allergenic
Favourable side effect profile
Cheap
Name 4 things that can help you with bony defects in TKA
Cement
Allograft
Autograft
Metaphsyeal sleeves
Cones
Stems
4 signs of loose cemented femoral components
Subsidence
Break in cement
lucency in cement/bone interface or cement/implant interface
pedestal formation
5 risk factors for peroneal nerve injury following THR?
- preoperative diagnosis of developmental dysplasia of the hip
- posttraumatic arthritis
- the use of a posterior approach
- lengthening of the extremity
- use of an uncemented femoral implant
What is the position for fusion of the knee?
15 degrees flexion
5-10 degrees ER