Receptors+ Control Of Heart Rate Flashcards
What type of receptor is pacinian corpuscle
Baro receptor
Where is pacinian corpuscle found
In the skin
E.g fingers soles of feet
And also tendons ligaments and joints
What is pacinian corpuscle made up of
Lamellae
Explain how applying pressure to Pacinian corpuscle changes membrane potential
Pressure causes membrane to be stretched
Sodium ion channel proteins open and Na+ diffuse in
Greater pressure means more channels open and more Na+ diffuse in
What is the maximum frequency of action potentials limited by
Refactory period
RODS
Evenly distributed throughout the maculla
Sensitive to all wavelengths of light (rhodopsin is the light sensitive pigment)
High visual sensitivity to low levels of light intensity
Low visual acuity- image unclear
Retinal convergence- several rods share a single bipolar neuron
Generator potentials combine to reach theeshold
Cones
Densely packed in fovea
Each cone cell (3) detects a specific wavelength of light
3 types of iodopsin
Iodopsin less sensitive than rhodopsin so requires higher light intensity
High visual acuity givin sharp image
This is because each cone cell is connected to a single bipolar neurone
Cone cells send separate impulses to the brain
What do photons do
Cause the light pigment to break down altering chemical structure
Leading to generator potential
What does retinal convergence lead to
Spatial summarion
What summation is cones an example of
Temporal
Heart muscle is myogenic
What dies this mean
Can iniate its own contraction
Heart controls and coordinates the regular contraction of the atria ventricles
How
SAN sends out an electrical impulse causing the atria to contract
Layer of non conductive tissue preventing it reaching the ventricles
Electrical impulse reaches the AVN
0.1 seconds to allow atria to empty out blood
AVN sends another electrical impulse
This travels down the bundle of His
Up the purkinje fibres
Ventricles contract from the apex of the heart upwards
Which nervous system is heart rate controlled by
Autonomic nervous system
What is the autonomic nervous system split into
Relation of the two branches
Sympathetic
Parasympthetic
Antagonistic- opposing effects
Neurotransmitter for sympathetic system
Noradrenaline
Neurotransmitter for parasympathetic nervous system
Acetylcholine
Membrane potential is the same whether medium or heavy pressure applied
Why
Threshold reached
So maximal response given /all or nothing principle
Parts of the myelin sheath are destroyed
Explain how this results in slower responses to stimuli
Less saltatory conduction/action potential
Impulses unable to jump from node to node
More depolarisation over area of membrane
Describe how pacinian corpuscle produces generator potential when stimulates
Increased pressure deforms the stretch mediated Na+ channel proteins
Causing them
To open
Na+ diffuse in
Depolarisation
When light falls on cell 3 no light seen. Bur when light falls on cell 3+4+5 light seen
Why
1 unit subthreshold whereas 3 units are above threshold
1 unit no impulses are sent to brain
3 units lead to an impulse sent /spatial summarion
Explain what causes vision in the fovea to be in colour
3 different types of cone cells sensitive to different wavelengths of light
Disadvantage of taking the drug in a pill
Drug would be destroyed by acid in stomach
What is the role of atp in myofibril contraction
Allows binding of myosin to actin
Atp provides energy which changes shape of myosin head
(Atp hydrolysed into Adp + Pi by Atp hydrolase) this provides the energy
Tropomyosin
Moves out of the way when Ca2+ bind
Allowing myosin to bind to actin forming crossbridge