Receptors And Clinical Scenarios Flashcards

1
Q

CC: A 41 yo gardener presents with salivation, miosis, and diarrhea. What caused this? What’s the MOA?

A

Organophosphate poisoning

(Organophosphates are cholinesterase inhibitors)

MOA: inhibition of acetylcholinesterase —> excess cholinergic stimulation of muscarinic receptors (that’s why he is leaky)

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