Receptors Flashcards
What does the Pacinian corpulse respond to?
Changes in mechanical pressure
What type of neurone is Pacinian corpulse?
A sensory neurone
Properties of Pacinian corpulse ( similar to all sensory neurones)
- specific to single type of stimlus
- Produces a generator potential by acting as a transducer
How does Pacinan corpulse specific to a single type of stimulus?
It will only respond to mechanical pressure
It will not respond to other stimuli such as heat,light or sound
How does sensory neurone produces a generator potential by acting as a transducer?
All stimuli involve change in some form of energy
It is a role of transducer to covert the change in form of energy by the stimulus into form - nerve impulses (can be understood by body)
Stimulus always involve change in some form of energy e.g light,sound or mechanical energy
The nerve impulse is another form of energy
Receptors convert/transudce one form of energy to another
Generator potential
What is a generator potentail?
Receptors in nervous system who convert the energy of stimulus into nerve impulse is a generator potential
How does Pacinian corpulse produce a generator potential by acting as a transducer?
Transduce the mechanical energy of stimulus into generator potential
What is an example of a mechanical stimuli that Pacinian corpulse respond to?
Pressure
Where does pressure occur in body?
Occur deep within the skin
Most abundant in fingers, soles of feet anf external gentalia
Occur in joints , liagments, tendons - enable the organism to know which joints are changing direction
Where is the sensory neurone located in Pacninan corpulse?
At the centre of layers of tissue - each separated by a gel
(giving an appearence of onion when cutting it)
What is a stretch-mediated sodium channel?
The sensory neurone ending at the Pacinian corpulse has a special type of sodium channel in its plasma membrane
It is called stretch-mediated sodium channel
Why are the names of the sodium channels of Pacninan corpulse weird?
Their permeability to sodium changes when they are deformed
e.g stretching
What happens to Pacninan corpulse when it is at resting state?
Stretch-mediated sodium channels of the membrane around the neurone of a Pacinina corpulse are too narrow to let sodium ions to pass along them
In this state of the neurone of Pacinian corpulse has a resting potential
What happens when pressure is applied to Pacinian corpulse?
- It is deformed of the membrane around its neurone becomes stretched
- Stretching widens the sodium channels in the membrane and sodium ions diffuse into the neurone
- The influx of sodium ion changes the potential of the membrane (i.e. becomes depolarised) thereby, producing generator potential
- Generator potential in turn creates an active potential (nerve impulse) that passes along the neurone via other neurones in CNS
Diagram of Pacinian corpulse