Receptors 2

Question 1

What is a receptor binding?

Answer 1

A signal detected when signalling molecules interact directly with a receptor

Question 2

What is a lingand?

Answer 2

Signalling molecule

Question 3

What are hydrophilic messengers detected by?

Answer 3

Membrane bound receptors

Question 4

What are hydrophobic messengers detected by?

Answer 4

Signal receptors in the cell

Question 5

What are the 3 min membrane receptors?

Answer 5

G protein coupled receptor
Receptor tyrosine receptors
Ion channel receptors

Question 6

What does the GDP being bound cause?

Answer 6

Inactive G protein and switch off

Question 7

What happens when the GTP is bound?

Answer 7

Active G protein and switch is on

Question 8

What are examples of pathways that use G proteins?

Answer 8

Whooping cough
Cholera
Botulism

Question 9

What are receptor tyrosine kinases?

Answer 9

Enzymes which add phosphate groups

Question 10

What do receptors that exist as monomers contain?

Answer 10

Extracellular ligand binding site
Membrane spanning region
Intracellular tail containing multiple tyrosines

Question 11

Is the binding of ligand reversible?

Answer 11

Yes

Question 12

What controls how often signalling occurs in GCPR?

Answer 12

Ligand concentration