Receptors

Question 1

What types of Acetylcholine Receptors are there.

Answer 1

Nicotinic

Muscarinic

Question 2

Features of Nicotinic ACh receptors

Answer 2

Ligand-gated Ionotropic (Ion channels)

Afinity to Nicotine

Question 3

Features of Muscarinic ACh receptors

Answer 3

Metabotropic (Not a channel)

Afinity to Muscarine

Question 4

What neurotransmitters effect Adrenergic receptors

Answer 4

Norepinephrine (Noradrenaline)

Epinephrine (Adrenaline)

Question 5

Where are alpha-1a,b,c subtype of Adrenergic receptors located

Answer 5

Vascular smooth muscle

Heart

Question 6

Agonist and Antagonist for alpha-1a,b,c Adrenergic receptors and their effects

Answer 6

Agonist - Methoxamine (Hypotension - Raise BP)

Antagonist - Doxazosin (Hypertension - Lower BP)

Question 7

Where are alpha-2a,b,c subtypes of Adrenergic receptor located

Answer 7

CNS
Platelets
Nerve Terminals

Question 8

Agonist and Antagonist for alpha-2a,b,c Adrenergic receptors and their effects

Answer 8

Agonist - Guanfacine (Hypertension - Lower BP)

Antagonist - Yohimbine

Question 9

Name the 3 types of Beta Receptors and their locations

Answer 9

B1 - Heart
B2 - Respiratory, Uterine, Skeletal
B3 - Fat Cells

Question 10

Examples and actions of B Agonist and Antagonist

Answer 10

Agonist
Isoproterol (Increase HR, Cardiac Output)
Salbutamol - Asthma
Antagonist -
Propranolol (Decrease HR, Cardiac Output)
Bisoprolol
Timolol - Glaucoma Treatment