Receptor Types in Adrenergic System Flashcards
Beta 1
1) Heart –> increase HR, increase force of contraction
2) Kidney–>renin secretion
Beta 2
1) Arterioles (and arteries in skeletal muscle, coronary) –> dilation
2) Bronchial Muscle, Pregnant Uterus –> relaxation
3) Several Sites –> increased metabolism
Beta 3
Adipose Tissue (lipocytes) –> increase lipolysis and thermogenesis
Alpha 1
1) Arterioles in skin, mucosa, viscera, kidney (Resistance Vessels)–>constriction
2) Veins –> constriction
3) Uterus and spleen –> contraction
Alpha 2
1) Presynaptic nerve endings –> inhibit NE Release and ACh Release (in the gut)
2) Postsynaptic in CNS –> decreased peripheral sympathetic tone
Dopamine 1
Renal, mesenteric and cerebral arterioles –> dilation