Recent advances in pediatric CPB / Test 3/3

Question 1

The primary goal of improving CPB has been ?

Answer 1

Smaller, Simpler, Safer, and more biocompatible.

Question 2

What is the name of the 1st oxygenator that specifically designed for the neonatal patient and became available in the US in 2007 ?

Answer 2

Sorin D100

Allowed very safe minimum operating levels of
as low as 10mL.

Question 3

What did the study of the D100 show ?

Answer 3

Required 37% less prime volume 
Resulted in:
Less blood transfusions.
Less ventilation time.
Less post operative bleeding

Question 4

An impressive feature of the new oxygenator was that it could adequately oxygenate blood at high flow rates of up to ?

This translates on being able to use these oxygenators in patients as large as ?

Answer 4

2 L/m

15 k/g

Question 5

What is the name of the first oxygenator by TERUMO that has an integrated ALF ?

Answer 5

Capiox FX Oxygenator

Question 6

When using oxygenators with integrated ALF, what can we expect?

Answer 6

Lower inotrope score
Decreased ventilation time
Decreased hospital stay

Question 7

Mast mounted pumps can lead to significant reductions in what ?
They also have an improved ability to safely perform CPB on patients as small as ?

Answer 7

↑Hct.
↓ Prime Volume
↓ Blood Use

3.2 kg

Question 8

Tubing can account for approximately ___ of the prime volume of neonatal CPB circuits?

Answer 8

3/4

Question 9

What are the primary uses of a hemoconcentrator (UF) device ?

Answer 9

removal of extravascular water
removal of LMW solutes
↑Hct

Question 10

Concentrate platelets & plasma Using low prime volume devices translates into what ?

Answer 10

more blood in the venous reservoir

Question 11

Current trand is to shift from high K+ depolorazing based CLP to ?

Answer 11

Hyperpolarizing or modified polarizing CLP that offers:
Similar myocardial protection
Longer dosing intervals
Reduction in circuitry complexity

Question 12

Custodial-Histadine-Tryptophan-Ketoglutorate =

Answer 12

Transplant preservation solution

Question 13

Del Nido Formula ?

Answer 13

1:4 hyperpolarizing blood based solution
Administered at 4 - 6 degree celcius.
Patients 40 kg = 1 L of CLP is MAX dose

Question 14

Hemochron Jr stats ?

Membrane surface area :
Prime Volume:
Max Ultra Filtration rate:

Answer 14

Membrane surface area : 0.09 M2
Prime Volume: 8 ml
Max Ultra Filtration rate: 30 ml/min

Question 15

Hemochron Jr mini ?

Membrane surface area :
Prime Volume:
Max Ultra Filtration rate:

Answer 15

Membrane surface area : 0.07 M2
Prime Volume: 14 ml
Max Ultra Filtration rate: 12 ml/min