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Immunoserology > Recall Questions > Flashcards

Recall Questions Flashcards

1
Q

The most immunogenic blood group Antigen next to Rh D

A

KELL Antigen

Immunogenecity:
ABO> RhD> Kell

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2
Q

The disease carried by Christopher Columbus crew from New world to Old world is _

A

SYPHILIS

New to Old

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3
Q

The disease carried from Old world to New world

A

SMALL POX

Old to New

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4
Q

The most common screening test for possible fetal blood in Rh D (-) mother is _

A

ROSETTE TEST (Qualitative)

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5
Q

What is the main advantage of Gel Technology

A

Standardization

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6
Q

What antigen of P. falciparum is being detected by the Malaquick Standby Malaria test?

A

HRP II (Histidine Rich Protein II)

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7
Q

The Screening Test for HIV

A

ELISA

Must be positive ELISA 2x

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8
Q

The confirmatory test for HIV

A

WESTERN BLOT

Must be positive Western Blot 1x

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9
Q

Dengue Antigen detected in serum of infected patients as early as day 1 to day 18 is post-onset of symptoms infection

A

NS1 (Non-Structural Antigen)

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10
Q

Cook who killed several people by transmitting TYPHOID FEVER

A

Mary Mallon

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11
Q

Year of T cell receptor gene discovery

A

1984

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12
Q

1 vial of RhIg will supress immunization of ___ mL of Rh (+) whole blood

A

30 mL

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13
Q

Red cell antigen modified in Acquired B phenomenon

A

A antigen

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14
Q

The C3 convertase of the classical pathway is _

A

C4b2a

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15
Q

The most common complement deficiency

A

C2

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16
Q

The most severe complement fraction deficiency

17
Q

Anti-PP1Pk is formerly known as

A

Anti-Tja

Tumor of Mrs. J

18
Q

Pepsin fragments antibody molecule into

19
Q

Most common gene in asian

20
Q

Serological Tests for which disease may give false (+) results if the patient has LYME disease?

a. HIV
b. Syphilis
c. Hepatitis B
d. Hepatitis C

A

B. SYPHILIS

  • Lyme disease - caused by borrelia burgdorferi (spirochete)
  • Syphilis - caused by spirochete
21
Q

Which Blood component has the longest expiration date?

a. Platelet concentrates
b. Cryoprecipitate
c. Fresh Frozen Plasma
d. Frozen RBCs

A 
D. FROZEN RBCs 
--
Shelf life: 
a. Platelet concentrates --> 5 days 
b. Cryoprecipitate --> 1 yr 
c. Fresh Frozen Plasma --> 1 yr 
d. Frozen RBCs --> 10 yrs
22
Q

Which antibody is indicative of chronic active hepatitis?

a. Anti-smooth muscle antibodies
b. Anti-smith
c. Anti-DSDNA
d. Anti-CCP (Cyclic citrunillated peptide)

A

B & C - SLE
D - Rheumatoid

23
Q

The nurse station requested for the closed-system whole blood unit of a gunshot patient be packed. Which of the ff. conforms with the expiration date?

a. Expires in 24 hrs, packing causes the exp. to change
b. Expires in 24 hrs, due to the risk of contamination
c. None of the above
d. Both A &B

A

C. NONE OF THE ABOVE
**
Blood unit is a closed system

24
Q

A patient with a history of marrow transplants is in need of certain blood components. Which of the ff. is the best method to reduce GVHD (Graft vs. Host disease)?

a. irradiation
b. washing
c. Transfuse blood in aliquots
d. None of the above

A

B. Washing - removes plasma proteins (usually done in allergic patients)
C. Transfuse blood in aliquots - To PREVENT circulatory overload

25
Q

Blood bags contain different preservatives. Which of the ff. acts on ionized calcium?

a. Adenine
b. Phosphate
c. Glucose
d. Citrate

A 
D. Citrate (chelates calcium) 
-- 
A. Adenine- Increased ADP levels 
B. Phosphate- source of 2,3-DPG to promote oxygen release 
C. Glucose- for nutrition
26
Q

Which of the ff. substances gain antigenicity only when coupled to a protein carrier?

a. Agglutinins
b. Agglutinogens
c. Haptens
d. Opsonins

A

c. HAPTENS
- -
a. Agglutinins
b. Agglutinogens - Stimulates agglutination
d. Opsonins

27
Q

Which of the ff. tests is a serological test for the diagnosis of RICKETTSIAL infections?

a. Widal test
b. Weil-Felix Test
c. Blondheim test
d. Monospot test

A

b. WEIL-FELIX
- -
a. Widal test - Salmonella Typhi
b. Blondheim test- Differentiates Myoglobinuria vs. Hemoglobinuria
d. Monospot test - for IM (Infectious mononucleosis) diagnosis caused by EBV

28
Q

Which of the ff. is a dependent form of hepatitis?

a. Hepa A
b. Hepa B
c. Hepa C
d. Hepa D

A

Hepa A, B, C –> stand alone viruses
Hepa D–> Dependent on HEPA B virus for its replication (BUT IS THE MOST SEVERE FORM since there is coinfection of Hepa B and V!!!!!!!)

29
Q

A patient screens positive for the virus discovered by Luc Montagnier, which serves as the reference laboratory for the confirmatory of the disease?

a. Sacred Heart Hospital
b. San Lazaro Hospital
c. Lung Center of the Phil.
d. East Ave. Medical Center

A

B. SAN LAZARO
* Luc Montagnier - HIV
–
Lung Center - Reference lab for CLINICAL CHEM.
East Ave. - Reference lab for DRUG TESTING

Immunoserology (3 decks)

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