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Hema 2 > Readings > Flashcards

Readings Flashcards

1
Q

What causes Superficial Bleeding

A

Platelet Defect or Vascuar Disorder

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2
Q

What causes Deep Tissue Bleeding

A

Plasma Clotting Factor Deficiencies

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3
Q

Superficial Bleeding is characterized by

A

Petechiae
Epistaxis
Gingival bleeding

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4
Q

Deep Tissue Bleeding is characterized by

A

Hematomas
Hemarthrosis

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5
Q

Abnormal IN VITRO clot retraction

A

GLANZMANN
THROMBASTHENIA

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6
Q

Less affected by abnormal clot retraction and fibrinogen binding

A

Type II Diabetes

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7
Q

BSS does not respond to:

A

Riscotecin

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8
Q

Hermansky Pudlak Syndrome is linked to what Chromosome

A

19

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9
Q

Hermnsky Pudlak Syndrome is characterized by ___ appearance of platelet

A

Swiss Cheese Platelet

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10
Q

Defective lysosomal function in a variety of cells

A

Hermansky Pudlak Syndrome

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11
Q

Tyrosinase positive oculocutaneous albinism

A

Hermnsky Pudla Syndrome

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12
Q

Partial oculucutaneous albinism

A

Chediak Higashi Syndrome

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13
Q

85% progresses to Lymphocytic proliferation in the liver, spleen, and marrow with macrophage accumulation in tissues

A

Chediak Higashi Syndrome

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14
Q

There is a frequen pyogeni bacterial infections

A

Chediak Higashi Syndrome

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15
Q

Giant lysosomal Granules

A

Chediak Higashi Syndrome

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16
Q

WAS is caused by mutation in what WAS gene

A

Short arm of X chromosome Xp. 11.23 that encodes fr a 502-amino acid protein

17
Q

Phenotypes present in WAS

A

50% WAS
50% XLT

18
Q

Feature of diagnostic importance in WAS

A

Microthrmobocytes

19
Q

Patients lack the ability to make Anti-Polysaccharide atibodies

A

Eczema Thrombocytopenia Immunodeficiency Syndrome

20
Q

Classic form of WAS

A

ETIS

21
Q

TAR is characterized by congenital absence of

A

Radial bones

22
Q

90% of cases have thrombocytopenia

A

TAR

Hema 2 (1 decks)

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