RCT Flashcards
1
Q
What is equipoise and why does this justify RCT’s?
A
Equipoise = no current known evidence that the intervention is inferior to the current treatment gold standard
2
Q
What is the power calculation for an RCT?
What is an accepted value?
A
1 - probability of a type 2 error
80-90%
3
Q
What is the significance calculation for an RCT?
What is an accepted value?
A
It is the probability of a type 1 error
Less than 5%
4
Q
What is a study end point?
A
Something that causes the study to be stopped
5
Q
In RCT’s, how do you calculate ARR?
A
Risk in control - risk in intervention
Is a number per factor of 10 patient years
6
Q
In RCT’s, how do you calculate RRR?
A
ARR / risk in control
Is a percentage
7
Q
What is the NNT?
A
1/ARR
