RBC Structure & Metabolism Flashcards
The word for too few red cells
Anemia
The word for too many red cells
Polycythemia
What is the production of red cells?
Erythropoiesis
Soft bony tissue between bony trabecular
Bone marrow
Hematopoietic tissue
Red marrow
Fat cells in bone marrow
Yellow marrow
Place where hematopoietic tissue meets the vascular area and cells are released into circulation.
Sinus area
The sinus area is lined with what kind of cell?
Reticuloendothelial cells (histiocytes/macrophages) of the RES (reticuloendothelial system)
Bone marrow cell that is specific to red cell lineage
Erythroblastosis
Bone marrow cell specific to white cell lineage.
Myeloblast
Platelet precursor cell
Megakaryocyte
Normal cells of bone marrow
Lymphocyte
6 maturation generalizations
- Size decreases
- N:C ratio decreases
- Condensation of DNA
- Nucleoli number decreases
- Microorganelles decreases
- Cytoplasmic components increase
5 RBC Maturation Nomenclature
- Pronormoblast
- Basophilic normoblast
- Polychromatophilic normoblast
- Orthochromic normoblast
- Diffusely basophilic erythrocytes
What is the RBC membrane functions?
Separates intracellular contents from the extracellular environment.
Why is it important for the RBC membrane to be flexible?
So that it can change shape to pass through capillaries and filtering spleen
RBC membrane is made up of what protein complex?
Biphospholipid protein complex
Integral proteins are responsible for linking what to the external environment?
Internal cytoplasm
This type of protein supports the membrane.
Skeletal proteins
The integral protein Glycoprotein A consists of what blood group antigens?
- ABO
- M
- N
This integral protein contains sialic acid, giving red cells their negative charge.
Glycophorin A
