RBC Indicies and Anemia Flashcards
When do Hollow Jolly Bodies occur?
During accelerated erythropoiesis
What do Hollow Jolly Bodies indicate?
A regenerative anemia
Nuclear remnant are related to what?
Hollow Jolly Bodies
How does basophilic stippling appear?
Deep blue dots
What are caused by lead poisoning (most commonly from ceramics from Mexico)?
Basophilic stippling
Distemper viral inclusion bodies aid in the diagnosis of what?
Distemper
What do Heinz bodies appear as?
Round blue protrusions
Denatured hemoglobin in Heinz bodies is due to what?
Zinc, oxidant drugs, and chemicals
What percentage is a normal amount of Heinz bodies for cats?
5%
Babesia is what type of organism?
Protozoan
Canines are affected by what form of babesia?
B. Canis and B. Gibsoni
How are babesia parasites transmitted in dogs?
Ticks
Another name for Babesia is?
Piroplasm
Felines are affected by what babesia?
B. Felis
Horses are affected by what babesia?
B. Equi
How does babesia appear?
Maltese cross
How is babesia transmitted in horses?
By dermacentor ticks
B. Bigemina =
Texas cattle fever
B. Bovis =
Red water fever
Reasons for anemia
Decreased production
Increased production
Condition that involves O2 carrying capacity of RBCs
Clinical signs of anemia
Pale mucous membrane
Lethargic
Increased respiratory rate
Collapse
Most common types of anemia
Hemolytic
Hemorrhagic
Iron deficiency
Production disorders
Is anemia a diagnosis?
No
Are reticulocytes present in regenerative anemia?
Yes
How long is does it take for a response with Regenerative Anemia?
4-7 days
Do horses release reticulocytes with regenerative anemia?
No
Are reticulocytes present with nonregenerative anemia?
No
Nonregenerative anemia =
Usually bone marrow disorder
Reticulocytes =
Immature RBCs
How to reticulocytes appear?
Clumps of blue granules
What stain is used on reticulocytes?
NMB (which is…?)
Normal reticulocyte ranges for dogs?
0-1.5%
Normal reticulocyte ranges for cats?
Punctate & aggregate
Punctate: 1.5-10%
Aggregate: up to 0.4%
What species do you count aggregate with?
Cats
Reticulocyte count procedure requires what?
Equal amounts whole blood and NMB
How long do you wait on a reticulocyte count?
10-15 minutes then make the blood smear
Calculation in reticulocyte counts?
in 10 fields / 10
Absolute reticulocyte count =
Reticulocyte % times RBC Count
What indicates strong regenerative anemia?
nRBCs
What stage are nRBCs in?
Metarubricyte