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HEMA LEC MIDTERM > RBC > Flashcards

RBC Flashcards

1
Q

Refers to erythrocytes wherein the central light area of
the cell is larger and paler than the normal

A

Hypochromic cell

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2
Q

Normal size of red blood cell

A

7-8 um

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3
Q

Red cells which have an increased hb content and
wherein the central light area is smaller than the normal

A

Hyperchromic cell

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4
Q

MCH of Hypochromic

A

<27 pg/cell

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5
Q

MCH of Normochromic

A

27-31
pg/cell.

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6
Q

MCH of Hyperchromic

A

> 31 pg/cell.

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7
Q

example of Hypochromic cell.

A

Spherocytes

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8
Q

This condition wherein the red cell are stained with
various shades of blue with tinges of pink.

A

Polychromatophilia or Polychromasia or Diffuse Basophilia

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9
Q

Condition where in the red cells appear pale

A

HYPOCHROMASIA

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10
Q

2 possible causes of hypochromasia:

A

 Dec hb concentration
 Abnormal thinness of the cells

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11
Q

Most common type of
anemia and this is also
the anemia, which is
easy to treat.

A

IDA (Iron Deficiency
Anemia)

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12
Q

A problem in the heme
synthesis. There is a blockage of iron in the
photophorphyrin.

A

Sideroblastic anemia

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13
Q

Another type of anemia. The problem here is the
alpha and beta globin chain. It is possible that these
globin chains are not present.

A

Thalassemia

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14
Q

The grading would depend on the area of central pallor.

A

HYPOCHROMASIA GRADING

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15
Q

Condition wherein the red cell are deeply stained to
abnormal thickness of
cells.

A

HYPERCHROMASIA

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16
Q

Abnormal shape of RBC wherein there is no central
pallor

A

Spherocytosis

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17
Q

Either caused by Vitamin B12 deficiency or the Folic
Acid deficiency.

A

Megaloblastic anemia

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18
Q

AD in HYPOCHROMASIA

A
  • IDA
  • sideroblastic anemia
  • thalassemia
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19
Q

AD in HYPERCHROMASIA

A
  • megaloblastic anemia
  • macrocytosis
  • spherocytosis
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20
Q

Condition where in the red cells vary in size both macrocytes and microcytes coexist on the same smear.

A

ANISTOCYTOSIS

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21
Q

AD in normocytes

A

hemolytic anemia and
aplastic anemia.

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22
Q

there is a premature
destruction of the red blood cells in which the RBC
cannot reach the 120 days.

A

hemolytic anemia

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23
Q

the target here is the bone
marrow. If a patient has aplastic anemia, all of
his/her rbcs, wbcs, and platelets will fall to low
levels.

A

Aplastic anemia

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24
Q

hallmark of aplastic anemia

A

Pancytopenia

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25
Q

Defect of macrocyte

A

Abnormal nuclear maturation but normal
cytoplasmic maturation

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26
Q

AD in macrocyte

A

Non-Megaloblastic anemia myelodysplatic
syndrome
 Chronic liver disease
 BM failure
 Reticulocytosis

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27
Q

Defect of microcyte

A

Abnormal cytoplasmic maturation but normal
nuclear maturation

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28
Q

Mitosis found in:

A

 Iron deficiency anemia
 Thalassemia
 Hemolytic anemia
 Hb E disease

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29
Q

Large oval-shaped red cell which is 9-12 um

A

MEGALOCYTE

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30
Q

Megalocytosis is found in

A

Megaloblastic anemias like pernicious anemia

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31
Q

Red cells exhibit variation in shape

A

poikilocytosis

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32
Q

Problems in shape could be due to

A

carbohydrates, lipids, and proteins

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33
Q

Normal cells with a biconcave disc shape with
increased surface volume surface

A

DISCOCYTE

34
Q

Associated disease of discocyte

A

 Acute post hemorrhagic anemia
 Aplastic anemia

35
Q

ACANTHOCYTES other name

A

SPUR CELL

36
Q

ACANTHOCYTES also known as

A

thorn cells

37
Q

small dense RBC with few irregularly
SPACED projections of
varying length

A

ACANTHOCYTES

38
Q

Defect of spur cell

A

abnormal
membrane defect caused
by an increase
sphingomyelin and dec
in cholesterol and
phospholipid

39
Q

Thorn cells have
unevenly pointed
projections

A

ACANTHOCYTES

40
Q

Associated Disease in acanthocytes

A

Neuroacanthocytosis
Severe liver disease
hepatitis of the
newborn, as well as malabsorption

41
Q

BISCUIT CELL other name

A

(FOLDED RBC

42
Q

Cell membrane is folded

A

BISCUIT CELL

43
Q

Cell assumes
a “ Pocket book roll” appearance
or biscuit shape

A

FOLDED RBC

44
Q

AD in folder rbc

A

HbSC disease, HbCC diseas

45
Q

BURR CELL other name

A

ECHINOCYTES

46
Q

burr cell also known as

A

Crenated cells or Burr cells
under sea urchin

47
Q

Abnormal lipid
content of the membrane

A

burr cell

48
Q

cell with irregularly
spaced blunt processes,

A

BURR CELL

49
Q

AD in burr cell

A

Uremia, MAHA, liver ds, DIC, TTP, PK

50
Q

change in osmotic
pressure.

A

burr cell

51
Q

BLISTER CELL other name

A

bite cell

52
Q

G6P def. resulting to
accumulation of Heinz bodies

A

defect of bite cell

53
Q

cell w/ eccentric vacuoles
due to the plucked out Heinz body

A

blister cell or bite cell

54
Q

AD in bite cell

A

G6PD def., HUS MAHA

55
Q

CODOCYTES also known as

A

target cells, mexican hat, bull’s eye appearance

56
Q

Def. in
cholesterol, phospholipid
in the membrane Def in
Lecithin cholesterol acyl
transferase ( LCAT)

A

target cell

57
Q

: Cell w/ central area
of Hb surrounded by
colorless area and a
peripheral ring

A

codocyte

58
Q

TEARDROP CELL other name

A

dacrocyte

59
Q

Sometimes called as
pear-shaped with blunt
projections

A

DACROCYTE

60
Q

ADS in dacrocyte

A

Hemolytic Anemia, Megaloblastic Anemia, and
Myelodysplastic syndrome and Myelophthisic
anemia

61
Q

ELLIPTOCYTES also known as

A

ovalocytes

62
Q

described as
sausage form, pencil
form, and egg form

A

ovalocytes or elliptocytes

63
Q

SPHEROCYTES Also known as cells

A

ball-shaped cells

64
Q

Increase osmotic fragility

A

SPHEROCYTES

65
Q

ADS in spherocytes

A

 Hereditary spherocytosis
 Immune hemolytic anemia
 Extensive burns (along with schistocyte)

66
Q

SICKLE CELLS other name

A

drepanocyte

67
Q

thin and
elongated with pointed ends
and are well filled with Hb.

A

sickle cell

68
Q

SCHISTOCYTES other name

A

SCHIZOCYTE

69
Q

irregularly, contracted
cell; fragmented cell

A

SCHISTOCYTES

70
Q

Characterize by an
elongated or slit-like area
of central pallor

A

STOMATOCYTE

71
Q

Stomatocytosis is
found in:

A

 Alcoholic cirrhosis
 Hereditary
stomatocytosis
 Hepatobiliary disease
 Rh null syndrome

72
Q

AD in DIFFUSE BASOPHILIA

A

Hemolytic
anemia. After treatment for iron, vitamin B12, or folate
deficiency,

73
Q

appearance of BASOPHILIC STIPPLING

A

Blueberry bagel
appearance

74
Q

 ADC in BASOPHILIC STIPPLING

A

Lead poisoning
 Thalassemia
 Hemoglobinopathies
 Megaloblastic anemia
 Myelodysplastic syndrome

75
Q

Irregular clusters of small, light to dark blue
granules often near
periphery of the cell.

A

PAPPENHEIMER BODIES

76
Q

stain used in PAPPENHEIMER BODIES

A

Perl’s Prussian Blue

77
Q

imparts“golf ball” appearance
to RBCs

A

Hgb H INCLUSIONS

78
Q

stacks of coins

A

. Rouleaux formation

79
Q

. Rouleaux formation can be seen in what condition?

A

multiple
myeloma, stromato globulin anemia.

80
Q

due to the way of
extraction

A

. Partially hemolyzed RBC

HEMA LEC MIDTERM (1 decks)

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