Rate Limiting Enzymes Flashcards
rate limiting enzyme of glycolysis
PFK-1
rate limiting enzyme of gluconeogenesis
fructose 1,6-bisphosphatase
rate limiting enzyme of TCA cycle
isocitrate dehydrogenase
rate limiting enzyme of of glycogenesis
glycogen synthase
rate limiting enzyme of glycogenolysis
glycogen phosphorylase
rate limiting enzyme of HMP shunt (pentose phosphate pathway)
glucose-6-phosphate dehydrogenase (G6PD)
rate limiting enzyme of purine synthesis
glutamine phosphoribosylphosphate amidotransferase (PRPP)
rate limiting enzyme of pyrimidine synthesis
CPS II
rate limiting enzyme of urea cycle
CPS I
rate limiting enzyme of fatty acid synthesis
acetyl CoA carboxylase
rate limiting enzyme of fatty acid oxidation
carnitine acyltransferase I (CAT I)
rate limiting enzyme of ketogenesis
HMG CoA synthase
rate limiting enzyme of cholesterol synthesis
HMG CoA reductase
what is the rate limiting enzyme of bile synthesis
7-alpha hydroxylase
what are 2 activators of PFK-1, the rate limiting enzyme of glycolysis
AMP
fructose 2,6-bisphosphate
what are 2 inhibitors of PFK-1, the rate limiting enzyme of glycolysis
ATP
citrate
what are 2 activators of fructose 1,6-bisphosphate, the rate limiting enzyme of gluconeogenesis
ATP
citrate
what is an activator of the isocitrate dehydrogenase, the rate limiting enzyme of the TCA cycle
ADP
what are 2 inhibitors of isocitrate dehydrogenase, the rate limiting enzyme of the TCA cycle
ATP
NADH
what are 3 activators of glycogen synthase, the rate limiting enzyme of glycogenesis
glucose 6-phosphate
insulin
cortisol
what are 2 inhibitors of glycogen synthase, the rate limiting enzyme of glycogensis
epinephrine
glucagon
what are 3 activators of glycogen phosphorylase, the rate limiting enzyme of glycogenolysis
epinephrine
glucagon
AMP
what are 3 inhibitors of glycogen phosphorylase, the rate limiting enzyme of glycogenolysis
glucose 6 phosphate
insulin
ATP
what activates G6PD, the rate limiting enzyme of the HMP shunt
NADP+
what inhibits G6PD, the rate limiting enzyme of the HMP shunt
NADPH
what 2 molecules activate CPS II, the rate limiting enzyme of pyrimidine synthesis
ATP
PRPP
what inhibits CPS II, the rate limiting enzyme of pyrimidine synthesis
UTP
what 3 molecules inhibit PRPP, the rate limiting enzyme of purine synthesis
GXP
AXP
IMP
what activates CPS I, the rate limiting enzyme of the urea cycle
NAG
what 2 molecules activate acetyl CoA carboxylase, the rate limiting enzyme of FA synthesis
insulin
citrate
what molecule inhibit acetyl CoA carboxylase, the rate limiting enzyme of FA synthesis
glucagon
what molecule inhibits CAT I, the rate limiting enzyme of fatty acid oxidation
malonyl CoA
