Rate Determining Enzymes

Question 1

Gluconeogenesis

Answer 1

F 1-6 bisphosphatase

+ citrate
- AMP, F 2-6 BP

Question 2

FA synthesis

Answer 2

ACC (acetyl Co-A carboxylase) - uses biotin

+ insulin, citrate
- glucagon, palmitoyl Co-A (part of beta-oxid)

Question 4

Glycogenesis

Answer 4

Glycogen synthase

+ Insulin, cortisol, G6P
- Glucagon, epinephrine

Question 6

PPP

Answer 6

G6P hydrogenase

+ NADP
- NADPH

Question 7

Beta-oxidation of FA

Answer 7

Carnitine acyl-transferase

• Malonyl CoA

Question 9

Glycolysis

Answer 9

PFK-1

+ F2-6 BP, AMP
- ATP, citrate

Question 10

TCA cycle

Answer 10

Isocitrate dehydrogenase

+ ADP
- NADH

Question 11

Glycogenolysis

Answer 11

Glycogen phosphorylase

+ epinephrine, glucagon, AMP
- G6P, insulin, ATP