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Cram Material > Rat Strains Quiz > Flashcards

Rat Strains Quiz Flashcards

1
Q

Diabetes insipidus

A

Brattleboro

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2
Q

Large granular lymphocytic leukemia

A

F-344

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3
Q

Intersitital cell tumor

A

F-344

(Leydig cell)

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4
Q

Corneal mineralization

A

F-344

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5
Q

Susceptible to E. cuniculi

A

Nude

(T-cell deficient - autosomal recessive)

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6
Q

Mega-small intestine

A

Ednrb

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7
Q

Seizures

A

Wistar

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8
Q

Polycystic Kidney Disease

A

Han:SRPD-cy

(autosomal dominant)

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9
Q

Pancreatic islet cell tumor

A

Sprague-Dawley

(more common females)

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10
Q

Hydronephrosis

A

Brown Norway (BN) - right kidney

Gunn - right kidney

Sprague-Dawley

also Wistar - certain strains

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11
Q

Control for hypertension rat

A

Wistar Kyoto (WKY)

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12
Q

Sensitive to Sendai

A

Brown Norway (BN)

Lewis (LEW)

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13
Q

Myeloma

A

LOU/C

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14
Q

Chronic myocardial disease

A

Sprague-Dawley

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15
Q

Diabetic Peripheral Motor Neuropathy

A

Wistar Bonn Kobori

(WBN/Kob)

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16
Q

Transverse vaginal septum

A

Wistar

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17
Q

Hirschprung’s Disease

A

Ednrb

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18
Q

Childhood absence epilepsy (petit mal)

A

Wag/Rij

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19
Q

Plasmacytomas

A

LOU/C

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20
Q

Spontaneous retinitis pigmentosa

A

eSS

WistarHanover (WH)

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21
Q

Autoimmune thyroiditis

A

Buffalo (BUF)

Lewis (autoimmune disease, not thyroiditis)

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22
Q

Inducible transplantable myeloid leukemia

A

Brown Norway (BN)

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23
Q

Polyarteritis Nodosa

A

Sprague-Dawley (SD)

SHR

Mendel Sherman MALES

24
Q

Intravascular hemolysis

A

Long-Evans Cinnamon

25
Q

Lacks L-gulono-gamma-lactone oxidase

A

Osteogenic disorder Shionogi (ODS)

26
Q

WIlson’s Disease

A

Long Evan’s Cinnamon (LEC)

(mutation causing fulminant hepatitis by 4 months old - death within 1 week)

Survivors develop hepatocellular carcinoma 1-1.5 years –> WIlson’s model

27
Q

Bladder carcinoma

A

Brown Norway (BN) - males

28
Q

Pituitary chromophobe adenomas (pars distalis)

A

Sprague-Dawley

Wistar

F-344 (most common in females) as well

29
Q

Morris hepatoma

A

Buffalo (BUF)

30
Q

Mononuclear cell leukemia

A

Wistar-Furth (WF)

31
Q

Hypertension

A

SHR

Fawn Hooded

Dahl/Salt Sensitive

32
Q

Eosinophilic granulomatous pulmonary inflammation

A

Brown Norway (BN)

33
Q

Production if IgG autoantibody

A

LOU/C

34
Q

Decreased serum thyroxine

A

Dwarf Rat

35
Q

Aging

A

F-344

(gerontology)

36
Q

Diabetes RESISTANT

A

BBDR/Wor

Infect with Rat Parvo –> autoimmune diabetes (increases expression of macrophage cytokines)

37
Q

Multiple sclerosis

A

Lewis (LEW)

Dark Agouti (DA)

38
Q

Type II diabetes

A

BB

Wistar

Zucker Diabetic Fatty (ZDF)

eSS

39
Q

Nephrocalcinosis

A

F-344

40
Q

Chronic Progressive Nephropathy

A

F-344

Sprague Dawley

41
Q

Piebald

A

Ednrb

42
Q

Obesity

A

Zucker

(Lepr gene, fa mutation on chromosome 5 - autosomal recessive)

43
Q

Juvenile insulin-dependent diabetes mellitus

A

BB/Wor

44
Q

Resistant to chronic progressive nephropathy

A

Wistar

Long-Evans

45
Q

Prostatic adenocarcinomas

A

ACI

Copenhagen (COP)

46
Q

Auricular chondritis

A

Wistar

47
Q

Crigler-Najjar Syndrome

A

Gunn

48
Q

Hydrocephalus

A

Sprague-Dawley

49
Q

Congenital genitourinary anomalies

A

ACI

50
Q

Type 4 hyperlipoproteinemia

A

Obese SHR

(autosomal recessive)

51
Q

Hypochromic, microcytic anemia with abnormal iron metabolism

A

Belgrade

(Nramp2 gene)

52
Q

Jaundice, kernicterus

A

Gunn (autosomal recessive)

53
Q

Resistant to Sendai (lesions less severe)

A

F-344

54
Q

Low incidence of nephrocalcinosis

A

Sprague-Dawley

Wistar

55
Q

Congenital aganglionosis

A

Ednrb

56
Q

High incidence mammary benign fibroadenomas

A

Sprague-Dawley

(50%)

57
Q

Megacolon

A

Ednrb

Cram Material (9 decks)

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