Rapid Review Flashcards
precipitants of hemolytic crisis in patients with G6PD deficiency
fava beans, sulfonimides, and antimalarials
Pure RBC aplasia
Diamond Blackfan anemia
medications and viruses that lead to aplastic anemia
HIV, EBV, Parvo B19, Hep, chemo, sulfonamides, chloramphenicol
how to distinguish polycythemia vera from secondary polycythemia
both have increase in hct and RBC mass, but PCV should have normal O2 sat and low epo levels
Pentad of TTP
FAT RN- Fever, anermia, thrombocytopenia, renal dysfct, and neuro abn
HUS triad
acute renal failure, thrombocytopenia, and anemia
TX TTP
emergent large- volume plasmapheresis, steroids, antiplatlets NO PLT TRANSFUSION
Tx hemophilia
desmopressin for A; or factor VIII or IX
Tx vWille
desmopressin, FFP or cryo
fever, bone pain, splenomegaly, pancytopenia
blast crisis
electrolyte changes in tumor lysis syndrome
decreased Ca, increased K, P and uric acid
a significant cause of morbidity in thalassemia patients, Tx?
Iron overload; use deferoxamine
menigitis in neonates; cause; tx
GBS, E coli, and Listeria; gentamicin and amp
meningitis in infants; cause; tx
pneumo, meningococcus, H influ; cefotaxime and vanc
neutropenic nadir postchem
7-10 d
most common cancers to met to the brain
lung, breast, skin, kidney and GI
Tx guillian barre
IVIG or plasmapheresis; AVOID steroids
Indications for renal and bladder US
infant and children <24 mo with first febrile UTI; recurrent febrile UTIs in kids, UTS in kid of any age with family hx of renal or urologic disease, htn, or poor growth, kids not responsive to meds
indications for endometrial biopsy
> 45 with abnormal bleeding or postmen bleeding; if <45 abnormal bleeding PLUS unopposed estrogen, failed medical management or lynch syndrome
sudden severe chest pain radiating to the back, htn, decrescendo diastolic murmur
aortic dissection
osteitis fibrosa cystica
bony pain, d/t excessive osteoclastic resorption of bone leading to replacement with fibrous tissue; seen primarily with parathyroid carcinoma