Rapid Review

Question 1

precipitants of hemolytic crisis in patients with G6PD deficiency

Answer 1

fava beans, sulfonimides, and antimalarials

Question 2

Pure RBC aplasia

Answer 2

Diamond Blackfan anemia

Question 3

medications and viruses that lead to aplastic anemia

Answer 3

HIV, EBV, Parvo B19, Hep, chemo, sulfonamides, chloramphenicol

Question 4

how to distinguish polycythemia vera from secondary polycythemia

Answer 4

both have increase in hct and RBC mass, but PCV should have normal O2 sat and low epo levels

Question 5

Pentad of TTP

Answer 5

FAT RN- Fever, anermia, thrombocytopenia, renal dysfct, and neuro abn

Question 6

HUS triad

Answer 6

acute renal failure, thrombocytopenia, and anemia

Question 7

TX TTP

Answer 7

emergent large- volume plasmapheresis, steroids, antiplatlets NO PLT TRANSFUSION

Question 8

Tx hemophilia

Answer 8

desmopressin for A; or factor VIII or IX

Question 9

Tx vWille

Answer 9

desmopressin, FFP or cryo

Question 10

fever, bone pain, splenomegaly, pancytopenia

Answer 10

blast crisis

Question 11

electrolyte changes in tumor lysis syndrome

Answer 11

decreased Ca, increased K, P and uric acid

Question 12

a significant cause of morbidity in thalassemia patients, Tx?

Answer 12

Iron overload; use deferoxamine

Question 13

menigitis in neonates; cause; tx

Answer 13

GBS, E coli, and Listeria; gentamicin and amp

Question 14

meningitis in infants; cause; tx

Answer 14

pneumo, meningococcus, H influ; cefotaxime and vanc

Question 15

neutropenic nadir postchem

Answer 15

7-10 d

Question 16

most common cancers to met to the brain

Answer 16

lung, breast, skin, kidney and GI

Question 17

Tx guillian barre

Answer 17

IVIG or plasmapheresis; AVOID steroids

Question 18

Indications for renal and bladder US

Answer 18

infant and children <24 mo with first febrile UTI; recurrent febrile UTIs in kids, UTS in kid of any age with family hx of renal or urologic disease, htn, or poor growth, kids not responsive to meds

Question 19

indications for endometrial biopsy

Answer 19

> 45 with abnormal bleeding or postmen bleeding; if <45 abnormal bleeding PLUS unopposed estrogen, failed medical management or lynch syndrome

Question 20

sudden severe chest pain radiating to the back, htn, decrescendo diastolic murmur

Answer 20

aortic dissection

Question 21

osteitis fibrosa cystica

Answer 21

bony pain, d/t excessive osteoclastic resorption of bone leading to replacement with fibrous tissue; seen primarily with parathyroid carcinoma