Rapid review Flashcards

1
Q

Abdominal pain, ascites, hepatomegaly

A

Budd-Chiari syndrome

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2
Q

Achilles tendon xanthoma

A

Familial hypercholesterolemia (decrease LDL receptor signaling)

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3
Q

Adrenal hemorrhage, hypotension, DIC

A

Waterhouse-Friderichsen syndrome (meningococcemia)

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4
Q

Athlete with polycythemia

A

Secondary to erythropoietin injection

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5
Q

Back pain, fever, night sweat, weight loss

A

Pott disease

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6
Q

Bilateral hilar adenopathy, uveitis

A

Sarcoidosis

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7
Q

Blue sclera

A

Osteogenesis imperfecta (type 1 collagen defect)

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8
Q

Bluish line on gingiva

A

Burton line (lead poisoning)

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9
Q

Bone pain, bone enlargement, arthritis

A

Paget disease of bone

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10
Q

Bounding pulse, diastolic heart murmur, head bobbing

A

Aortic regurgitation

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11
Q

Butterfly facial rash with Raynaud in young female

A

SLE

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12
Q

Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities

A

McCune-Albright syndrome (mosaid G-protein signaling mutation)

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13
Q

Gowers sign

A

Child uses arm to stand up from squat seen in Duchenne muscular dystrophy

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14
Q

Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria

A

McArdle disease

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15
Q

Deep, labored breathing/hyperventilation

A

Kussmaul respiration seen in Diabetic ketoacidosis

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16
Q

Dilatd cardiomyopathy, edema, alcoholism or malnutrition

A

Wet beriberi (Thiamine deficiency)

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17
Q

Dysphagia, glossitis, iron deficiency anemia

A

Plummer-Vinson

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18
Q

Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells (2)

A
  1. Mycosis fungoides (cutaneous T-cell Lymphoma)
  2. Sézary syndrome (Mycosis fungoides + malignant T cells in blood)
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19
Q

Fever, chills, headache, myalgia follwing antibiotic treatment for syphilis

A

Jarisch-Herxheimer reaction

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20
Q

Fibrous plaques in soft tissue of penis

A

Peyronie disease

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21
Q

Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands

A

Peutz-Jeghers syndrome

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22
Q

Hepatosplenomegaly, osteoporosis, neurologic symptoms

A

Goucher (glucocerebrosidase deficiency)

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23
Q

Hereditary nephritis, sensorineural hearing loss, cataracts

A

Alpot syndrome

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24
Q

Male child, recurrent infections, no mature B cells

A

Bruton disease (x-linked agammaglobulinemia)

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25
Q

Mucosal bleeding and prolonged BT

A

Glanzmann thrombasthenia (defect in platelet aggregation due to lack of Gp2b/3a)

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26
Q

Myopathy (infantile hypertorphic cardiomyopathy), exercise intolerance

A

Pompe

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27
Q

Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia

A

MS

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28
Q

Palpable purpura on buttocks/legs, joint pain, abdominal pain, hematuria

A

Henoch-Schönlein purpura (IgA vasculitis affecting skin and kidney)

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29
Q

Pruritic, purple, polygonal planar papules and plaques

A

Lichen planus

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30
Q

Pupil accommodates but doesn’t react

A

Argyll Robertson pupil due to neurosyphilis

31
Q

Rapidly progressive leg weakness that ascends following GI/upper respiratory infection

A

Guillain-Barré

32
Q

Rash on palms and soles (3)

A
  1. Coxsackie A
  2. Secondary syphilis
  3. Rocky Mountain spotted fever
33
Q

Anticentromere AB seen in

A

Scleroderma (CREST)

34
Q

Antidesmoglein AB seen in

A

Pemphigus vulvaris

35
Q

Antihistone AB seen in

A

Drug-induced SLE

36
Q

Drugs causing SLE (4)

A
  1. Hydralazine
  2. INH
  3. Phenytoin
  4. Procainamide
37
Q

Azurophilic peroxidase + granular inculsions in granulocytes and myelopblasts

A

Auer rods seen in AML

38
Q

Bacitracin sensitive

A

S. pyogenes

39
Q

Bacitracin resistant

A

S. agalactiae

40
Q

Basophilic nuclear remnants in RBC

A

Howell-Jolly bodis seen in splenectomy or nonfunctional spleen

41
Q

Basophilic stippling of RBCs seen in

A

Lead poisoning or sideroblastic anemia

42
Q

Cardiomegaly with apical atrophy seen in

A

Chags disease (Trypanosoma cruzi)

43
Q

Circular grouping of dark tumor cells surrounding pale neurofibrils

A

Homer-Wright rosettes

44
Q

Homer-Wright rosettes seen in (3)

A
  1. Neuroblastoma
  2. Medulloblastoma
  3. Retinoblastoma
45
Q

Disarrayed granulosa cells in eosinophilic flud

A

Call-Exner bodes seen in granulosa-theca tumor

46
Q

Eosinophilic cytoplasmic inculsion in liver cells

A

Mallory body seen in alcoholic liver

47
Q

Intranuclear eosinophilic droplet-like bodies

A

Cowdry type A bodes in HSV or CMV

48
Q

Large lysosomal vesicles in phagocytes, immunodeficiency seen in

A

Chédiak-Higashi disease

49
Q

Novobiocin sensitive

A

S. epidermidis

50
Q

Novobiocin resistant

A

S. saprophyticus

51
Q

Onion skin periosteal reaction seen in

A

Ewing sarcoma (malignant round-cell tumor)

52
Q

Optochin sensitive

A

S. pneumoniae

53
Q

Optochin resistant

A

Viridan

54
Q

Pseudopalisading tumor cells on brain biopsy

A

Glioblastoma multiforme

55
Q

Absence seizure treatment

A

Ethosuximide

56
Q

Acute gout treatment (2)

A
  1. NSAIDs
  2. Colchicine
57
Q

ADHD treatment (2)

A
  1. Methylphenidate
  2. Amphetamines
58
Q

Bipolar disorder treatment (4)

A
  1. Lithium
  2. Valproate
  3. Carbamazepine
  4. Lamotrigine
59
Q

Breat cancer in postmenopausal women treatment

A

Aromatase inhibitor (anastrozole)

60
Q

Candida treatment (3)

A
  1. Amphotericin B (systemic)
  2. Nystatin (oral thrush)
  3. Azoles (Vaginitis)
61
Q

Chronic gout treatment (3)

A
  1. Probenecid
  2. Allopurinol
  3. Febuxostat
62
Q

CML treatment

A

Imatinib

63
Q

Chronic hepatitis treatment

A

IFN-α

64
Q

Cryptococcus neoformans treatment

A

Fluconazole

65
Q

Enterococci treatment

A

Vancomycin/ampicillin + AG

66
Q

HER2/neu + breat cancer treatment

A

Trastuzumab

67
Q

Hypertriglyceridemia treatment

A

Fibrate

68
Q

Influenza treatment (2)

A
  1. Rimantadine
  2. Oseltamiver
69
Q

Legionella treatment

A

Erythromycin

70
Q

TB treatment

RIPE

A
  • Rifampin
  • INH
  • Pyrazinamide
  • Ethanbutol
71
Q

N. gonorrhoeae treatment

A

Ceftriazone

72
Q

Ringworm infection treatment (3)

A
  1. Terbinafine
  2. Griseofulvin
  3. Imidazole
73
Q

SIADH treatment (3)

A
  1. Demeclocycline
  2. Lithium
  3. Vasopressin receptor antagonists
74
Q

Sporothrix treatment

A

Oral potassium iodide