Rapid review Flashcards
Abdominal pain, ascites, hepatomegaly
Budd-Chiari syndrome
Achilles tendon xanthoma
Familial hypercholesterolemia (decrease LDL receptor signaling)
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen syndrome (meningococcemia)
Athlete with polycythemia
Secondary to erythropoietin injection
Back pain, fever, night sweat, weight loss
Pott disease
Bilateral hilar adenopathy, uveitis
Sarcoidosis
Blue sclera
Osteogenesis imperfecta (type 1 collagen defect)
Bluish line on gingiva
Burton line (lead poisoning)
Bone pain, bone enlargement, arthritis
Paget disease of bone
Bounding pulse, diastolic heart murmur, head bobbing
Aortic regurgitation
Butterfly facial rash with Raynaud in young female
SLE
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities
McCune-Albright syndrome (mosaid G-protein signaling mutation)
Gowers sign
Child uses arm to stand up from squat seen in Duchenne muscular dystrophy
Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria
McArdle disease
Deep, labored breathing/hyperventilation
Kussmaul respiration seen in Diabetic ketoacidosis
Dilatd cardiomyopathy, edema, alcoholism or malnutrition
Wet beriberi (Thiamine deficiency)
Dysphagia, glossitis, iron deficiency anemia
Plummer-Vinson
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells (2)
- Mycosis fungoides (cutaneous T-cell Lymphoma)
- Sézary syndrome (Mycosis fungoides + malignant T cells in blood)
Fever, chills, headache, myalgia follwing antibiotic treatment for syphilis
Jarisch-Herxheimer reaction
Fibrous plaques in soft tissue of penis
Peyronie disease
Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
Peutz-Jeghers syndrome
Hepatosplenomegaly, osteoporosis, neurologic symptoms
Goucher (glucocerebrosidase deficiency)
Hereditary nephritis, sensorineural hearing loss, cataracts
Alpot syndrome
Male child, recurrent infections, no mature B cells
Bruton disease (x-linked agammaglobulinemia)
Mucosal bleeding and prolonged BT
Glanzmann thrombasthenia (defect in platelet aggregation due to lack of Gp2b/3a)
Myopathy (infantile hypertorphic cardiomyopathy), exercise intolerance
Pompe
Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia
MS
Palpable purpura on buttocks/legs, joint pain, abdominal pain, hematuria
Henoch-Schönlein purpura (IgA vasculitis affecting skin and kidney)
Pruritic, purple, polygonal planar papules and plaques
Lichen planus
Pupil accommodates but doesn’t react
Argyll Robertson pupil due to neurosyphilis
Rapidly progressive leg weakness that ascends following GI/upper respiratory infection
Guillain-Barré
Rash on palms and soles (3)
- Coxsackie A
- Secondary syphilis
- Rocky Mountain spotted fever
Anticentromere AB seen in
Scleroderma (CREST)
Antidesmoglein AB seen in
Pemphigus vulvaris
Antihistone AB seen in
Drug-induced SLE
Drugs causing SLE (4)
- Hydralazine
- INH
- Phenytoin
- Procainamide
Azurophilic peroxidase + granular inculsions in granulocytes and myelopblasts
Auer rods seen in AML
Bacitracin sensitive
S. pyogenes
Bacitracin resistant
S. agalactiae
Basophilic nuclear remnants in RBC
Howell-Jolly bodis seen in splenectomy or nonfunctional spleen
Basophilic stippling of RBCs seen in
Lead poisoning or sideroblastic anemia
Cardiomegaly with apical atrophy seen in
Chags disease (Trypanosoma cruzi)
Circular grouping of dark tumor cells surrounding pale neurofibrils
Homer-Wright rosettes
Homer-Wright rosettes seen in (3)
- Neuroblastoma
- Medulloblastoma
- Retinoblastoma
Disarrayed granulosa cells in eosinophilic flud
Call-Exner bodes seen in granulosa-theca tumor
Eosinophilic cytoplasmic inculsion in liver cells
Mallory body seen in alcoholic liver
Intranuclear eosinophilic droplet-like bodies
Cowdry type A bodes in HSV or CMV
Large lysosomal vesicles in phagocytes, immunodeficiency seen in
Chédiak-Higashi disease
Novobiocin sensitive
S. epidermidis
Novobiocin resistant
S. saprophyticus
Onion skin periosteal reaction seen in
Ewing sarcoma (malignant round-cell tumor)
Optochin sensitive
S. pneumoniae
Optochin resistant
Viridan
Pseudopalisading tumor cells on brain biopsy
Glioblastoma multiforme
Absence seizure treatment
Ethosuximide
Acute gout treatment (2)
- NSAIDs
- Colchicine
ADHD treatment (2)
- Methylphenidate
- Amphetamines
Bipolar disorder treatment (4)
- Lithium
- Valproate
- Carbamazepine
- Lamotrigine
Breat cancer in postmenopausal women treatment
Aromatase inhibitor (anastrozole)
Candida treatment (3)
- Amphotericin B (systemic)
- Nystatin (oral thrush)
- Azoles (Vaginitis)
Chronic gout treatment (3)
- Probenecid
- Allopurinol
- Febuxostat
CML treatment
Imatinib
Chronic hepatitis treatment
IFN-α
Cryptococcus neoformans treatment
Fluconazole
Enterococci treatment
Vancomycin/ampicillin + AG
HER2/neu + breat cancer treatment
Trastuzumab
Hypertriglyceridemia treatment
Fibrate
Influenza treatment (2)
- Rimantadine
- Oseltamiver
Legionella treatment
Erythromycin
TB treatment
RIPE
- Rifampin
- INH
- Pyrazinamide
- Ethanbutol
N. gonorrhoeae treatment
Ceftriazone
Ringworm infection treatment (3)
- Terbinafine
- Griseofulvin
- Imidazole
SIADH treatment (3)
- Demeclocycline
- Lithium
- Vasopressin receptor antagonists
Sporothrix treatment
Oral potassium iodide