Rapid Fire Facts - DIT Flashcards
Continuous Machinery-like heart murmur
Patent Ductus Arteries (PDA)
“Boot Shaped Heart”
Tetralogy of Fallot (infant) - RV Hypertrophy (COPD, pHTN, Adults)
Rib Notching
Coarctation of the Aorta
Most common congenital cardiac anomaly
Ventricular Septal Defect (VSD)
Most common congenital cause of early cyanosis
Tetralogy of Fallot
Sensitivity
A/(A+C), PID {positive in disease], 1-false negative rate
Specificity
D/(D+B), NIH [negative in health]
Positive Predictive Value (PPV)
A/(A+B), will increased with increased disease prevalence
Negative Predictive Value (NPV)
D/(D+C), will decreased with increased disease prevalence
Hepatomegaly, abdominal pain, ascities
Budd-Chiari Syndrome
Green/yellow corneal deposits
Wilson Disease
Low Serum Ceruloplasmin
Wilson Disease
Cirrhosis, Diabetes and hyperpigmentation
Hemochromatosis
Risk Factors for Hepatocellular Carcinoma?
HBV, HCV, Wilson, Hemochromatosis, α1 antitrypsin deficiency, Hepatic adenoma, Alcoholic cirrhosis
Uniateral facial drooping involving the forehead
Bell Palsy
Ptosis, miosis, and anhidrosis
Horner Syndrome
Most common Thyroid Cancer
Papillary Carcinoma
Cold Intolerance
Hypothyroism
Enlarged thyroid cell with ground-glass nuclei
“orphan Anne eyes” - Papillary Carcinoma
Relative Risk
A/(A+B) / C/(C+D)
Odds Ratio
A/B / C/D
Attributable Risk
A (exposed) - C (not exposed)
Absolute risk reduction
C/(C+D) [not tx] - A/(A+B) [tx]
Number needed to treat
1/Absolute risk reduction
Keratin pearls on skin biopsy
Squamous Cell Carcinoma
Most common malignant skin tumor
Basal Cell Carcinoma
Painful cyanosis of the fingers and toes, with hemolytic anemia
Cold Agglutinins
Red urine in the morning, and fragile RBCs
Paroxysmal Nocturnal Hemoglobinuria
Basophilic nuclear remnants in RBCs
Howell-Jolly Bodies
Autosplenectomy
Sickle Cell Disease
Drug used to treat sickle cell disease
Hydroxyurea
Most common opportunistic infection in HIV Patients
Pneumocystis jirovecii (PCP)
Prophylaxis for Cryptococcus in AIDS patients
Fluconazole
Prophylaxis for PCP in AIDS patients
Trimethoprim/Sulfamethoxazole (TMP-SMX)
Treatment for Sporothrix schenckii
Oral potassium iodine or Itraconazole
Treatment for oral candidiasis
Nystatin or fluconazole
Treatment for systemic candidiasis
Amphotericin B
Antiplatelet Antibodies
ITP
Bleeding disorder with GpIb deficiency
Bernard-Soulier disease
Most common inherited bleeding disorder
von Willebrand Disease
Low Potency Neuroleptic Drugs
Chlorpromazine, thioridazine
Clozapine
Agranulocytosis
Bilateral Hilar Adenopathy, uveitis
Sarcoidosis
Vasculitis and glomerulonephritis
Goodpasture syndrome and Wegener Granulomatosis
Anti-flomerular basement membrane antibodies
Goodpasture syndrome
Honeycomb lung on x-ray
Interstitial Fibrosis
“tennis racket” shaped cytoplasmic organelles
Birbeck granules (Eosinophilic Granulomatosis)
Treatment for Chronic hepatitis
Interferon - α
Most common cause of neural tube defects
Folate deficiency
Most common cause of congenital malformation in the US
Alcohol Use
Most common cause of congenital intellectual disability in the US
Fetal Alcohol Syndrome
Hyperflexible joints, arachnodactyly, aortic dissection, lens dislocation
Marfan Syndrome
Hereditary nephritis, cataracts, sensorineural hearing loss
Alport Syndrome
Unilateral facial drooping involving the forehead
Bell’s Palsy
“worse headache of my life”
Subarachnoid Hemorrhage
Lucid interval following head trauma
Epidural Hemorrhage
Bloody CSF on LP
Subarachnoid Hemorrhage
Most common cause of subdural hematoma
Rupture of Bridging Veins
Most common cause of epidural hematoma
Rupture of Middle Meningeal Artery
Treatment for Malignant Hyperthermia
Dantrolene
Treatment for absence seizures
Ethosuximide
Treatment for tonic-clonic seizures
Valproic Acid, Phenytoin, Carbamazepine
Amyloid deposits in gray matter of the brain
Senile plaques (Alzheimer Disease)
Drooling Farmer
Organophosphate Poisoning
Medial treatment for pheochromocytoma
α-antagonist
Selective α-antagonist used to treat BPH
Tamsulosin
Bounding pulses, head-bobbing, diastolic murmur
Aortic Regurgitation
Chest pain, pericardial friction rub, persistant fever occurring several weeks after an MI
Dressler Syndrome
Bone enlargement, bone pain, arthritis
Paget Disease of the Bone
Vertebral compression fractures
Osteoporosis
Positive anterior drawer sign
ACL injury
Swollen, hard, painful finger joints
Osteoarthritis
Swollen, boggy, painful finger joints
Rheumatoid arthritis
Cartilage erosion with polished bone beneath
Osteoarthritis
Swollen, red, acutely painful great toe joint
Gout
Positively birefringent rhomboid-shaped crystals
Pseudogout
Negatively birefringent needle-shaped crystals
Gout
Bamboo spine on x-ray
Ankylosing Spondylitis
HLA-B27
Seronegative Spondyloarthropathies
Anti-Smith and anti-dsDNA antibodies
SLE
Anti-histone antibodies
Drug induced lupus
Anti-centromere antibodies
CREST Scleroderma
Anti-topoisomerase antibodies
Diffuse Systemic Scleroderma
Anti-Jo-1 antibodies
Polymyositis
Anti-SSA and Anti-SSB antibodies
Sjogren syndrome
Facial rash and Raynaud phenomenon in a young woman
SLE
Arthritis, dry mouth, and dry eyes
Sjogren syndrome
Most common cause of death in SLE
Lupus nephropathy/nephritis
Keratin pearls on skin biopsy
Squamous Cell Carcinoma
Most common malignant skin tumor
Basal Cell Carcinoma
Most Common cancer in men
Prostate Carcinoma
Most common cause of urinary obstruction in men
Benign Prostatic HyperPLASIA
Most common treatment for erectile dysfunction
Phosphodiesterase Inhibitors
Dysplastic cervical cells with enlarged, dark nuclei
Koilocytes (HPV infections)
Diesthylstilbestrol (DES) exposure
Clear Cell Adenocarcinoma
Most common tumor in women
leiomyoma
Most common gynecologic malignancy in the US
Endometrial carcinoma
Most common gynecologic malignancy worldwide
Cervical Carcinoma
Chocolate cyst of the ovary
Endometriosis
Most common benign ovarian tumor
Serous Cystadenoma
Most common malignant ovarian tumor
Serous Cystadenocarcinoma
Disarrayed granolas cells in eosinophilic fluid
Call-exner bodies (Granulosa-thecal cell tumors)
Most common genetic cause of intellectual disability
Trisomy 21 (Down Syndrome)
Second most common genetic cause of intellectual disability
Fragile X Syndrome
Horseshoe kidney, congenital heart defects, streak ovaries, and cystic hygroma
Turner Syndrome
Rocker-bottom feet, clenched hands, microcephaly with prominent occiput and small jaw
Trisomy 18 (Edward Syndrome)
Most common cancer in women in the US
Breast Cancer
Most common benign breast tumor
Fibroadenoma
Most common malignant breast tumor
Invasive ductal carcinoma
Blue dome cyst in the breast
Fibrocystic Change
Treatment for ER (+) breast cancer
Tamoxifen
Red, Itchy, Swollen rash on the areola and nipple
Paget Disease of the Breast
Branching, filamentous Gram (+) rods with sulfur granules
Actinomyces israelii
Food poisoning due to exotoxin
S. aureus and Bacillus cereus
Osteomyelitis in sickle cell disease
Salmonella
Most common medication used for UTI prophylaxis
Trimethoprim-Sulfamethoxazole
Most common bacteria in a patient with strive kidney stones
Proteus (then Staph)
Standard treatment for T. pallidum
Penicillin G
Cellulitis from a dog or cat bite
Pasteurella multocida
A non-painful, indurated, ulcerated genital lesion
Chancre of primary syphilis
Moist, smooth, flat, white genital lesion
Condylomata late of secondary syphilis
Large bull’s eye rash
Erythema migrants due to Lyme disease
Calcified granuloma in the lungs, plus hillier lymphadenopathy
Ghon complex