Randomization Flashcards
1
Q
What does randomization provide to ethics?
A
- Makes study groups comparable with respect to unknown risk factors
- Removes investigator bias in allocation
- Ensures statistical tests will have valid false positive error rates.
- AVOIDS SELECTION BIAS.
2
Q
Who performs randomization and why?
A
Independent party to increase validity of study.
3
Q
What is blinding and what are types?
A
Blinding done to address bias; PPT study arm not known.
Unblinded
Single blind: PPT does not know
Double-blind: PPT and PI do not know
Triple-blind: PPT, PI, and monitoring committee do not know
