random review! Flashcards

1
Q

Aminoglycosides ROA

A

No ORAL - IV

- except neomycin oral; iv too toxic

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2
Q

CDAD give what

A

First line metronidazole

- then oral vancomycin

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3
Q

Atypical give what

A

Tetracycline

Macrolides

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4
Q

Pregnant women w Chlamydia

A

Macrolides!!!

- tetracycline has dentition accumulation hence contraI in pregnancy

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5
Q

oedema and anaemia and optic neuritis

- which drug given for MRSA?

A

Linezolid - think PBS

  • BMS
  • PN
  • Serotonin syndrome
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6
Q

Risk for CDAD?

A

Clindamycin
Tetracycline - superinfection
Fluoroquinolone

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7
Q

Whats maraviroc

A

Entry inhibitor

  • bind CCR5, block GP120
  • note is the only drug binding a host antigen
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8
Q

Whats ritonavir

A

PK enhancer

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9
Q

Whats enfuvirtide

A

ENtry inhibitor - subcutaneous injection

- bind GP41-CD4 block membrane fusion

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10
Q

Whats efavirenz

A

NNRTI

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11
Q

Phototoxicity?

A

FQ

Tetracycline

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12
Q

Nephrotoxicity

A

Aminoglycoside
Vancomycin
AmB - conventional

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13
Q

Ototoxicity

A

Aminoglycoside
Vancomycin
Macrolides (azithromycin),

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14
Q

Anemia, Thrombocytopenia

A

BMS
- linezolid

Folate B9 deficiency
- sulfonamide

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15
Q

Crystalluria

A

Sulfonamide

- drink more water

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16
Q

Tendonitis

A

Fluoroquinolone

17
Q

To avoid in G6PD

A

Sulfonamide
Co-trimoxazole

NITROFURANTOIN!!!

18
Q

Staining of teeth, stunt growth

A

Tetracycline

19
Q

Kernicterus

A

Sulfonamide

- displace bilirubin

20
Q

Red man syndrome

A

Infusion w Vancomycin

  • also NO,
  • also thrombophlebitis
21
Q

First line UTI

A

Oral Co-trimoxazole, Oral Nitrofurantoin NOT MEtro

FQ

22
Q

Which med need genetic testing to administer

A

Abacavir

- HLA-B 5701 - negative

23
Q

Gimme CYP inducers

Gimme CYP inhibitors

A

Anti-psychotics, Phenytoin; RIFAMPICIN, St John Wart
- glucocorticoids

HIV Protease Inhibitors - navirs
SSRI - 4
Macrolide + Fluoroquinolone 
Azoles
Grapefruit
Isoniazid