random review! Flashcards
Aminoglycosides ROA
No ORAL - IV
- except neomycin oral; iv too toxic
CDAD give what
First line metronidazole
- then oral vancomycin
Atypical give what
Tetracycline
Macrolides
Pregnant women w Chlamydia
Macrolides!!!
- tetracycline has dentition accumulation hence contraI in pregnancy
oedema and anaemia and optic neuritis
- which drug given for MRSA?
Linezolid - think PBS
- BMS
- PN
- Serotonin syndrome
Risk for CDAD?
Clindamycin
Tetracycline - superinfection
Fluoroquinolone
Whats maraviroc
Entry inhibitor
- bind CCR5, block GP120
- note is the only drug binding a host antigen
Whats ritonavir
PK enhancer
Whats enfuvirtide
ENtry inhibitor - subcutaneous injection
- bind GP41-CD4 block membrane fusion
Whats efavirenz
NNRTI
Phototoxicity?
FQ
Tetracycline
Nephrotoxicity
Aminoglycoside
Vancomycin
AmB - conventional
Ototoxicity
Aminoglycoside
Vancomycin
Macrolides (azithromycin),
Anemia, Thrombocytopenia
BMS
- linezolid
Folate B9 deficiency
- sulfonamide
Crystalluria
Sulfonamide
- drink more water
Tendonitis
Fluoroquinolone
To avoid in G6PD
Sulfonamide
Co-trimoxazole
NITROFURANTOIN!!!
Staining of teeth, stunt growth
Tetracycline
Kernicterus
Sulfonamide
- displace bilirubin
Red man syndrome
Infusion w Vancomycin
- also NO,
- also thrombophlebitis
First line UTI
Oral Co-trimoxazole, Oral Nitrofurantoin NOT MEtro
FQ
Which med need genetic testing to administer
Abacavir
- HLA-B 5701 - negative
Gimme CYP inducers
Gimme CYP inhibitors
Anti-psychotics, Phenytoin; RIFAMPICIN, St John Wart
- glucocorticoids
HIV Protease Inhibitors - navirs SSRI - 4 Macrolide + Fluoroquinolone Azoles Grapefruit Isoniazid
