Random Facts Flashcards
What meds should not be given with metoprolol and why
Paroxetine, fluoxetine, and Wellbutrin
Metabolized by same CYP450 enzyme; the antidepressants can increase the effects of metoprolol leading to SE
What’s susto & sx
Cultural syndrome (Spanish). Frightening/shocking event causes soul to leave body.
Symptoms include weight loss, fatigue, muscle pains, headache, diarrhea, unhappiness, troubled sleep, lack of motivation, and low self-esteem
Kava kava use and major SE
Anxiety & insomnia
Sedating and liver damage
3 antipsychotics & 1 antidepressant with QT prolongation
Ziprasidone, quetiapine, haldoperidol
Citalopram
Least sedating SSRIs
Prozac and lexapro
Medical med that increases risk SJS with lamictal
Tramodol
Mood stabilizer and antipsychotics with least weight gain
Lamictal
Ziprasidone, abilify, Latuda
Least sedating antipsychotic
Abilify
Labs for gout and hepatitis
Uric acid, LFT, CBC
Labs for antibiotics
CBC, RFT, LFT, electrolytes
Meds with risk agranulocytosis
Clozaril and carbamazepine
Meds that decrease effectiveness of OCP
Topamax, phenytoin, and antiepileptics in general
Med with risk SJS in Asians and why
Carbamazepine due to HLAB-1502 allele
Lab values that indicate agranulocytosis/DC med (clozaril or carbamazepine)
ANC < 1000
WBC < 2000-3000
What pre screening needed with clozaril
Cardiac due to risk cardiomyopathy
Meds that decrease SI
Lithium
Clozaril in schizophrenia specifically
Normal Cr and BUN
BUN to creatinine ratio
Cr 0.5-1.2
BUN 10-20
Ratio between 10:1 and 20:1
Want to start lithium. BUN 4.5
And Cr 4.5. Which value more concerning?
Cr due to risk of lithium toxicity (if Cr is high, kidneys not functioning well causing it to build up)
Impact sodium has on Lithium levels
Sodium 135-145
Low sodium means decreased lithium clearance and increased lithium levels
Meds that can increase lithium levels
NSAIDs, thiazides, ACEi and meds that decrease renal clearance like colchinine
Main neurotransmitters in addiction
Dopamine and GABA
Two main lab findings in infection
Increased CRP and WBC
Tx for NMS
DC offending agent
#1 bromocriptine
can then use dantrolene for muscle relaxation
Hallmark finding with MSE in schizophrenia
Impaired proverb interpretation