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PSA > Random Drug Facts > Flashcards

Random Drug Facts Flashcards

1
Q

Why should you not give trimethoprim in pregnancy

A

Folate antagonist

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2
Q

What are some drugs that cause postural hypotension

A

Bendroflumethiazide
Candesartan
Diltiazem
Isosorbide mononitrate

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3
Q

Why might a patient with hypertension complain of a persistent dry cough

A

ACE-I

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4
Q

What should you offer patients with essential hypertension who cannot tolerate ACE-I due to side effects

A

Angiotensin II receptor blocker

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5
Q

What needs to be monitored in a patient on ACE-I

A

eGFR - ACE-I may cause renal impairment

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6
Q

Why should tetracyclines (eg. doxycycline) not be given to patients under 12

A

Dental hypoplasia

May discolour teeth

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7
Q

Why should doxycycline not be given in pregnancy (or breastfeeding)

A

May be deposited in foetal bones and teeth

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8
Q

What is the drug of choice in treating DVT

A

LMWH
Dalteparin sodium,
Enoxaparin
Tinzaparin sodium

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9
Q

What is the ideal starting dose of a statin

A

20mg

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10
Q

What is the normal dose range for atenolol

A

25-100mg

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11
Q

In which patients is metformin contra-indicated

A

Those with renal impairment

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12
Q

What oral diabetes medication can cause hypoglycaemia

A

Pioglitazone

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13
Q

What medications cause urinary retention

A 
Opioid analgesics
Anticholinergics
General anaesthetics
Alpha adrenoreceptor agonists
Benzodiazepines
NSAIDs
Ca-channel blockers
Antihistamines
Alcohol
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14
Q

How does gliclazide work

A

Sulfonylurea - Enhance insulin secretion from islet cells in the pancreas

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15
Q

How would you monitor lithium therapy

A

Renal function tests as it can impair renal function

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16
Q

What LFTs would prompt you to discontinue statin therapy

A

Serum transaminases over 3x the upper limit of normal

17
Q

What drugs cause gingival hyperplasia

A

Phenytoin

Nifedipine

18
Q

What drugs cause macrocytosis

A

Phenytoin

Sulfasalazine

19
Q

What medication do you give to a pregnant woman with morning sickness

A

Oral antihistamine eg. cyclizine, promethazine

20
Q

What is akathisia

A

A movement disorder, characterised by restlessness and a compelling need to be in costant motion

21
Q

What drugs may cause akathisia

A

Domperidone

Metoclopramide

22
Q

What is a side effect of proton pump inhibitors

A

Hyponatraemia

They can precipitate the secretion of ADH, resulting in symptomatic hyponatraemia

23
Q

What is a significant side effect of ciclosporin

A

It can precipitate increases in BP, increasing the risk of stroke, MI and heart failure

24
Q

What medications should be prescribed by particular brand names

A

Carbamazepine
Ciclosporin
Theophylline

Different formulations may lead to clinically important changes in blood concentrations of the drugs.

25
Q

What are some medications that cause tachycardia

A

Anagrelide

Oxybutynin hydrochloride

26
Q

What are some drugs that can cause drowsiness

A

Gabapentin

Oxybutynin hydrochloride

27
Q

What drugs can cause hyperlipidaemia

A

Olanzapine
Lamivudine
Thiazide diuretics

28
Q

What is the treatment for scabies

A

Permethrin

29
Q

When is combined anti-platelet therapy justified

A

Patients who have had acute coronary syndrome within the previous year
Patients having a bare metal stent
Patients having a heart valve replacement

30
Q

What drugs cause photosensitivity

A

Thiazide diuretics

31
Q

What drugs combine with amiodarone to cause QT prolongation

A

Quinolone antibiotics eg. moxifloxacin

32
Q

What is a recognised side effect of venlafaxine

A

Increased BP

33
Q

What is a recognised adverse effect of methyldopa

A

Impaired renal function

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