Random Flashcards
Where is the Thymus derived from?
Third Pharyngeal pouch
Hypoplastic thymus in DiGeroge and SCID
Which Ab is the ONLY one that can cross the placenta?
IgG
IgG is the MAIN Ab for the 2ndary response to an antigen* (IgM is the primary (immediate) response)
IgG is the most abundant*
Provides passive immunity to infants
Which Ab does not fix complement?
IgA
Found in mucous membranes and is secreted in tears and saliva and mucus
What are the live-attenuated vaccines?
“BI-VAMPY”
BCG Influenza (intranasal) Varicella Adenovirus MMR Polio (Sabin) Yellow Fever
What are the killed/inactivated vaccines?
"RIP A-lways" Rabies Influenza (injection) Polio (Salk) A: Hep A
What do B-cell and T-cell deficiencies have a decreased immunity to?
B-cell: Bacterial infection
T-cell: Viral and Fungal infections
Where is Hexokinase Vs Glucokinase found?
Hexokinase: all tissue except liver and B-cells of pacrease
Glucokinase = Liver and b-cells of pancrea
What are the major precursors for gluconeogenesis?
Glycerol, Amino Acids, Lactate
-Make glucose for my “GAL”
What is the most abundant protein in the human body?
Collagen
High tensile strength and undergoes extensive post-translational modification
What other drug is given with 6-MP to prevent an adverse SE as well as increase the [6-MP]?
Allopurinol
6-MP turns into thio-IMP via HRGT, and is a purine analog, so allopurinol will help prevent gout and keep 6-MP level in the body high
What causes Glycolysis to produce ZERO ATP?
Arsenic
Which tissues are insulin DEPENDENT and what GLUT do they use?
Muscle and Fat: GLUT 4
Which bacteria has Vi Antigen as a VF?
Salmonella
Vi Antigen = Capsule
Which 3 bacteria are the most common causes of meningitis in people over 2 months of age?
Step. Pneumo, H. Influenza, N. Meningitis
Where is the highest visual sensitivity in the retina?
Fovea Centralis, which is inside the macula lutea (lateral to the optic disc)
Where does the Optic N. leave the retina?
Optic Disc