Random 1 Flashcards
15 yo. C/o sore testicle. Pain, testicle high, transverse, absent cremasteric reflex Dx?
Torsion of the testicle. Pain, testicle high, transverse, absent cremasteric reflex ddx: epididymo-orchitis, torsion of testicular appendix. rx: urgent surgical review
6 yo bib mum. Itchy rash after eating lunch. Now hoarse, croaky voice and cough. Dx? Apart from ABCs, most important part of rx?
Anaphylaxis. 0.01-0.5mg/kg adrenalin IM anterolateral thigh. May need to rpt every 5-10 mins t/f hospital
56 yo. Abdo pain. H/o heavy ETOH, Hep C pos. Signs of chronic liver disease on examination?
spider naevi (>3), palmar erythema, gynaecomastia, caput medusa, ascites, jaundice, asterixis (liver flap).
45 yo Liver disease. abdo pain. Most serious dx? Essential ix for dx? rx?
Spontaneous bacterial peritonitis. ix: positive bacterial culture results and polymorph leucocyte (PML) count >259 cells/mm3 from ascitic tap. rx: IV 3rd gen cephalosporin Long term antibiotic prophylaxis with bactrim.
Red flags for acute abdo pain in 20yo woman?
ectopic pregnancy appendicitis perforated viscous PID DKA Malignancy eg. ovarian cancer
3 yo boy. Awoke with dyspnoea. Barking cough Inspiratory stridor increased work of breathing +/- fever +/- wheeze Dx? Rx?
Croup rx: Minimal handling Mild- Mod: prednisone 1mg/kg stat and second dose next day. Must be free of stridor before d/c severe: Hospital. nebulised adrenaline and IV dexamethasone
68 yo man. Progressive dyspnoea. Sleeps on 3 pillows. h/o MI and stent. HT. CXR: enlarged heart Echo: LVEF 25%. mitral regurg. Dx? Rx:
Heart failure. salt restrict ACE - I B blocker Frusemide, spironolactone digoxin
37 yo woman. SOB and chest pain this AM. Risk factors for PE? What is the Wells score? When is a D-Dimer indicated?
Risks for PE: previous PE/DVT Recent immobilisation/surgery malignancy pregnancy smoking oestrogen based medications inherited thrombophilia Wells score used to predict likelihood of PE Use D-Dimer if low pre-test probability. Neg D-Dimer and Low Wells score (4 or less) excludes PE
60 yo caucasian man. Abdominal obesity (Waist circumference 95cm), high triglycerides, HT Dx? Rx?
Metabolic syndrome. Abdominal obesity PLUS any 2 of: High triglycerides Low HDL HT (>= 130/85) High BSL >=5.6 or dx T2DM Rx: Lifestyle: - quit smoking, reduce ETOH - normal BMI and waist - Mediterranean diet - low salt - Exercise Medications for HT and lipids as per CVD risk calculator
24 yo uni student. H/o glandular fever. 6 months of tired and fatigue every day. Normal examination. Dx? How to exclude alternative dx? Rx?
Chronic fatigue Syndrome Recommended ix for fatigue (NICE guidelines) Úrinalysis FBC LFT TSH ESR. CRP BSL Creatinine Calcium Coeliac screen CK Ferritin (young people only) Rx: CBT and graded exercise. Nil evidence for meds or alternative meds
42 yo woman. 4 yrs worsening lethargy, generalised body aches, poor sleep. H/o severe viral illness and divorce 5 yrs ago. Burning quality to pain and intermittent paraesthesia. Dx? Red flags? Rx?
Fibromyalgia. Red flags: older age at onset. weight loss, night pain, focal pain, fevers and sweats, neuro fearures, h/o malignancy Rx: Pt education, exercise, psychology, Meds: antidepressants (amitriptyline, duloxetine) SNRI milnacipran only medication on TGA for fibromyalgia Paracetamol and NSAIDs Manage comorbid conditions
43 yo woman. H/o coeliac. 6 months fatigue. Weight gain, poor appetite. Constipation. dry skin. Anaemia, hyponatraemia. Dx? Tests to confirm?
Hypothyroidism raised TSH, Low T3, T4 Check UECs to rule out Addisons as treatment of hypothyroidism can lead to adrenal crisis Anti-thyroid peroxidase = hashimoto Nil USS unless nodules or goitre
33 yo. Bilateral ptosis, muscle weakness. Sits forward with elbow on desk, supporting chin with hand. Dx? Rx?
Myasthenia gravis. Autoimmune Acetylcholine receptors attacked by antibodies Neurologist.
33 yo diffuse goitre TSH 12 (0.3-5.0) T4 2 (11-23) T3 3 (3.5-6.7) Dx? Which further ix necessary?
Hypothyroidism Anti thyroid peroxidase = hashimotos, most common cause in western countries +/-USS - some say only USS if nodule, some say if goitre or nodule
30 yo. Hypothyroidism, on thyroxine. Wants to fall pregnant and is concerned about taking medication during pregnancy. What do you advise about hypothyroidism in pregnancy?
Overt hypothyroidism associated with adverse pregnancy outcomes: impaired fetal neurocognitive development (low IQ), low birth weight, miscarriage, stillbirth. (All women) 150ug iodine supplement daily Monitor TSH 4 weekly. Adjust thyroxine as soon as pregnancy confirmed, usually 25-30% increase
45 yo woman. nervous, intolerant of heat, palpitations, weight loss, fine tremor. Sinus tachy on ECG. Dx?
Hyperthyroidism
38 yo woman, tachycardia, goitre, returned with bloods: TSH editing issue, won’t save.
Thyrotoxicosis due to Graves disease B blocker Antithyroid meds: carbimazole, propylthiouracil. Radioactive iodine, thyroidectomy (after imaging) Propylthiouracil preferred in pregnancy. Wait 6 months after radioactive iodine before pregnancy (men 4 months for turnover of sperm production)
40 yo on carbimazole for Graves. Has mouth ulcer, fever and sore throat. Dx?
Agranulocytosis. (Neutrophil count. Risk with carbimazole and ptu. Advise pt to stop med and see Dr if sx infection.
40 yo, just confirmed hashimotos. What dose of thyroxine would you start? How often would you monitor?
Final dose of thyroxine is usually 1.6mcg/kg or 50-200mcg/day. Start 50mcg (lower, 25mcg in elderly), increasing every 2 wks. Recheck TSH 6 wks (T4 has long half life)
7 yo. Recently started wetting the bed. Mum thinks is due to drinking too much past few weeks. Also weight loss. Dx?
T1DM random bsl urgent refer
65 yo T2DM. Just started sulphonylurea. 4kg weight gain. Why? How to manage?
Insulin and sulphonylureas can cause hypoglycaemia and increase weight. Hypo = eating more = more weight If low BSL advise 15g fast acting carb, wait 15 mins, recheck BSL, if still low, 15g slow acting carb
70 yo T2DM. HT high chol. Vision deteriorating over past 4 months. fundus photo and optical coherence tomography scans show: retinal haemorrhages, hard exudates extending to fovea, cystic macular oedema Dx? DDx? Rx?
Diabetic macular oedema fovea involved = significant vision issues. ddx. cataract, macular degeneration Argon laser photocoagulation, more recently intravitreal anti-VEGF agents. Fenofibrates (recent TGA for diabetic retinopathy).
DSM V diagnosis of Specific Learning Disorder (eg. dyslexia) ?
learning difficulties >6 mths despite extra help academic skills significantly below peers symptoms manifest in school age (sometimes adults) Intellectual disability, vision/hearing impairment, mental/neuro disorders and psychosocial ruled out
3 yo. 3 months dry cough, laboured breathing. fhx atopy and asthma Dx? Initial rx?
Asthma Pt/family education, triggers, non smoking, GPMP, asthma plan etc. Meds: reliever (salbutamol) 6 inh via spacer prn preventer: montelukast or ICS eg fluticasone 50mcg bd (rinse mouth)
Definitions of asthma 0-5yrs: symptom free for at least 6 wks at a time ? Symptoms more than once every 6 wks on average but nil sx between flare ups
- Infrequent intermittent asthma 2. frequent intermittent asthma
Asthma in 0-5yo Daytime sx more than once per week but not every day AND/OR Night time symptoms more than twice per month but not every week?
Mild persistent asthma