RADIOPHARMACEUTICALS

Question 1

Most commonly used radionuclide generator in nuclear medicine practice worldwide since its first commercial introduction in 1965

Answer 1

99 Mo - 99m TC Generator

Question 2

It is mainly used for lung ventilation scans and for the assessment of cerebral blood flow

Answer 2

Xenon-133

Question 2

The most common applications of Indium-111 are in __________

Answer 2

Labelling Blood Cells for Imaging Inflammatory Processes, Thrombi, and Proteins

Question 2

It was approved for the treatment of patients with relapsed or refractory, low-grade or follicular B-cell NHL

Answer 2

Indium-111 and Yttrium-90 Ibritumomab Tiuxetan (Zevalin)

Question 2

This is used for liver imaging

Answer 2

Yttrium-90 Labeled Microspheres

Question 3

It is eluted from the the Technetium 99m - Molybdenum 99 Generator with sterile isotonic saline

Answer 3

Technetium 99m-Sodium Pertechnetate

Question 4

Technetium 99m-Sodium Pertechnetate is used for:

Answer 4

1. Meckels Diverticulum Scintigraphy
2. Gastric Emptying Study
3. Salivary Gland Scintigraphy
4. Lachrymal Duct Scintigraphy
5. Thyroid Scintigraphy

Question 5

The two (2) commonly used diphosphonate compounds are:

Answer 5

1. Methylene Diphosphonate (MDP)
2. Hydroxymethylene Diphosphonate (HDP)

Question 6

What radiopharmaceutical is used for renal studies and glomerular filtration rate (GFR) determination ?

Answer 6

Technetium-99m Diethylenetriaminepentaacetic Acid (DTPA)

Question 7

It used to diagnose renal infection in children and in morphological studies of the renal cortex

Answer 7

Technetium-99m Dimercaptosuccinic Acid (DMSA)

Question 8

It was introduced initially under the brand name Cardiolite as a technetium-based radiopharmaceutical to replace Tl-201 in myocardial perfusion imaging.

Answer 8

Technetium-99m Methoxyisobutyl Isonitrile (SESTAMIBI)

Question 9

Used in the diagnosis of myocardial perfusion
abnormalities in patients with coronary artery
disease.

Answer 9

Techenetium-99m Tetrofosmin

Question 10

Primarily used in brain perfusion imaging, although it is used for leukocyte labeling
substituting 111 In-oxine.

Answer 10

Technetium-99m Hexamethylpropylene Amine Oxime (HMPAO)

Question 11

What radiopharmaceutical is used to evaluate hepatocyte function, rule out or prove acute cholecystitis, demonstrate commo bile duct partial or complete obstruction, and verify hepatic bile duct atresia in infants ?

Answer 11

Technetium-99m Iminodiacetic Acid (IDA)

Question 11

The radiopharmaceutical of choice for lung perfusion scan with ventilation scan to
exclude pulmonary embolism

Answer 11

Technetium-99 m Macroaggregated Albumin (MAA)

Question 12

99m TC HSAM is used for (2):

Answer 12

1. Pulmonary Perfusion Scintigraphy
2. Determination of Right-to-left Shunts

Question 13

HSAM stands for

Answer 13

Human Serum Albumin Microspheres

Question 13

It is used for pulmonary perfusion scintigraphy and determination of right-to-left shunts

Answer 13

Technetium-99m Human Serum Albumin Microspheres (HSAM)

Question 13

99m TC Sulfur Colloid is used for (4):

Answer 13

1. Bone Marrow
2. Spleen Scintigraphy
3. Liver Scintigraphy
4. Lymphoscintigraphy