RADIOPHARMACEUTICAL DRUGS

Question 1

Gallium-67 Gallium Citrate

Answer 1

GALLIUM-67

Chemical Symbol: 67Ga
Chemical Form: Gallium-67 Gallium Citrate
Half-life : 3.26 days
Manufacturer(s): Covidlen, Lantheus Medical Imaging
Trade name(s): Neoscan (GE), DuPont Ga-67, Mallinckrodt Ga-67

Diagnostic use: Useful to demonstrate the presence/extent of:

Hodgkin’s disease

Lymphoma

Bronchogenic carcinoma

Aid in detecting some acute inflammatory lesions

Question 2

Fluorine-18 florbetapir

Answer 2

FLUORINE-18

Chemical symbol : 18F
Chemical form : fluorine-18F florbetapir
Half life : 109.771 minutes
manufacturer : eli lily
trade name : amyvid

diagnostic use
Indicated for PET imaging of patients with suspected prostate cancer recurrence based upon elevated blood prostate-specific antigen (PSA).

Question 3

Indium-111 capromab pendetide

Answer 3

INDIUM-111

Chemical symbol : 111ln
Chemical form: Indium-111 capromab pendetide
Half life: 2.80 days
Manufacturers : Jazz pharmaceuticals
Trade name: ProstaScintR

Diagnostic use:

A diagnostic imaging agent in newly-diagnosed patients with biopsy-proven prostate cancer, thought to be clinically-localized after standard diagnostic evaluation, who are at high-risk for pelvic lymph node metastases.

Question 4

Indium-111 Diethylenetriamine pentaacetic Acid (DTPA)

Answer 4

INDIUM-111
Chemical symbol : 111ln
Chemical form: Indium-111 Diethylenetriamine pentaacetic Acid (DTPA)
Half life: 2.80 days
Manufacturers :GE Healthcare
Trade name: Indium DTPA In 111

Diagnostic use:

For use in radionuclide cisternography, Cerebro spinal fluid imaging

Question 5

fluorine-18 sodium flouride

Answer 5

FLUORINE 18

Chemical symbol : 18F
Chemical form : Fluorine_18 sodium fluoride
half life : 109.771 minutes
Manufacturer : various
trade name : none

diagnostic use : PET bone imaging agent to delineate areas of altered osteogenesis

Question 6

Indium-111 Chloride

Answer 6

INDIUM-111

Chemical symbol : 111ln
Chemical form:Indium-111 Chloride
Half life: 2.80 days
Manufacturers :GE Healthcare, Covidien
Trade name: Indiclor (Nycomed), Mallinckrodt In-111Cl

Diagnostic use:

For labeling monoclonal antibodies and peptides

Question 7

Fluorine-18 fludeoxyglucose

Answer 7

FLUORINE-18
Chemical Symbol: 18F
Chemical Form: Fluorine-18 fludeoxyglucose
Half-life: 109.771 minutes
Manufacturer: Various
Trade name(s):

Diagnostic use:
As a PET imaging agent to:
Assess abnormal glucose metabolism in oncology
Assess myocardial hibernation
Identify regions of abnormal glucose metabolism associated with foci of epileptic seizures

Question 8

Carbon-14 urea

Answer 8

CARBON 14

chemical symbol : 11c
chemical form : carbon-14 urea
Half life : 5730 years
manufacturer : kimberly clark
trade name : PYtest
diagnostic use : Detection of gastric urease as an aid in the diagnosis of H.pylori infection in the stomach

Question 9

Carbon-11 choline

Answer 9

CARBON 11

chemical symbol: 11C
Chemical form : Carbon 11-choline
half life : 20.334 minutes
trade name : none

diagnostic use :
Indicated for PET imaging of patients with suspected prostate cancer recurrence based upon elevated blood prostate-specific antigen (PSA) levels following initial therapy and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging (MRI) to help identify potential sites of prostate cancer recurrence for subsequent histologic confirmation

Question 10

Indium-111 Chloride

Answer 10

INDIUM-111

Chemical symbol : 111ln
Chemical form:Indium-111 Chloride
Half life: 2.80 days
Manufacturers :GE Healthcare, Covidien
Trade name: Indiclor (Nycomed), Mallinckrodt In-111Cl

Diagnostic use:
For labeling monoclonal antibodies and peptides