Radiolucencies Flashcards

1
Q

Why do radiolucencies occur on radiographs

A

Thinning of hard tissue relative to adjacent area

Reduced hard tissue mineral (which reduces the density of a tissue e.g. caries)

A less dense area will allow X-ray photons to pass through them much more readily. As more photons hit the X-ray beam detector, we get a more radiolucent appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

List some radiolucencies that represent normal anatomy

A

Maxillary antrum/sinus (aerated, radiolucent sinus present above the apices of upper posterior teeth. Not filled with bone but air which has very low density, therefore appears radiolucent)

Mental foramen

Submandibular fossa (an area where the mandible is thinner. This fossa should be relatively symmetrical but can mimic a lesion in the mandible sometimes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the maxillary antrum?

A

Also known as the maxillary sinus

A cavity that is not filled with bone but air which has very low density therefore presents as an aerated radiolucent sinus located above the apices of upper posterior teeth.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the submandibular fossa

A

An area where the mandible is thinner.

This fossa should be relatively symmetrical but can mimic a lesion in the mandible sometimes.

Won’t be as well defined or have corticated margins whereas most pathologies will have these features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

List some artefacts that can result in a radiolucency

A

Overexposure-
May result in more photons reaching the detector to give a more radiolucent appearance on the radiograph

Superimposition of an air shadow-
E.g., if a patient hasn’t pressed their tongue to the roof of their mouth on an OPT, we would get a more radiolucent area (which represents the air shadow of the oral cavity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When describing a radiolucency, what features do we have to consider

A

Site-
Mandible or maxilla?
Above or below ID canal (above = more likely to be odontogenic/from tooth forming tissues, below = less likely to be odontogenic
Relation to dentition or a tooth (periapical = at the apex of a tooth, peri-coronal = around the crown of a tooth, peri-radicular = related to the root of a tooth)

Size (important for surgical planning)

Shape (informs differential diagnoses and planning access and removal)

Margin (informs differential diagnoses and planning access and removal)

Locularity (informs differential diagnoses and planning access and removal)

Effect on adjacent structures (teeth, floor of the antrum/sinus, ID canal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does a well defined, corticated radiolucency with smooth margins suggest about the pathology causing it?

A

If a lesion has corticated, well defined, smooth margins, it suggests the lesion is growing quite slowly and is more likely to be a benign pathology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does an ill-defined radiolucency with moth eaten or punched out margins with no cortication suggest about the pathology causing it?

A

If a lesion’s margins are moth eaten or ill defined, cannot be distinguished from other areas of a structure very well, or there’s a punched out margin with no cortication, it suggests the lesion is growing rapidly. More likely to be seen where there’s infection or malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

List the effects a radiolucency may have on adjacent structures

A

Damage to teeth-
Resorption
Displacement
Delayed eruption (if a lesion arises in a peri-coronal position, it may delay the eruption of the tooth, impeding its eruption pathway into the mouth)
Loss of associated lamina dura (a thin line of dense bone found around the root of a tooth adjacent to the PDL)

ID canal-
Displacement
Erosion of its cortices

Maxillary antrum-
Upwards displacement of maxillary antrum floor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

List some pathological causes of radiolucencies

A

Cysts-
Odontogenic (inflammatory or non-inflammatory/developmental)
Non-odontogenic

Tumours-
Benign
Malignant (primary or secondary)

Bone related lesions-
Giant cell lesions
Cemento-osseous dysplasias (in its early stages)

Bone diseases-
Osteoporosis
Sickle cell disease
Hyperparathyroidism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is a cyst?

A

Pathological epithelial lined cavity within the tissues, filled with fluid, semi fluid or gas that is not derived from the accumulation of pus.

However can become secondarily infected if it becomes large enough (in which case, it will become pus filled)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Radiographically a PA granuloma and and a PA cyst are impossible to differentiate. Apart from a biopsy sent to histopathology, what could be used to differentiate between the 2?

A

Size may give a hint or an indication of what pathology the radiolucency is likely to be, from the 2.

The larger the lesion, the more likely it is to be a radicular cyst.

Once radiolucencies are above 1.5cm, about 1/3rd of them will be radicular cysts, whereas about 1/3rd of radiolucencies under 1cm will be PA granulomas

(However we can get large granulomas or small cysts)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the radiographic features of a radicular cyst?

A

Well-defined, uni-locular, corticated radiolucency associated with the apex of a tooth that is almost always non-vital.

No cortication evident at the apex of the tooth as this is where the infection causing the cyst originates.

There may also be some loss of cortication if the cyst is infected.

Adjacent teeth may be displaced but they are rarely resorbed as a result of a radicular cyst

Some buccal expansion may be evident

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are some indications of non-vitality, where the tooth has a suspected radicular cyst

A

Indications of the tooth’s non-vitality may include large restorations, deep caries, RCT, previous history of trauma to the tooth, dense in dente (which can form a pathway to the pulp causing non-vitality)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Upper 2’s are frequently affected by radicular cysts. What is one explanation for this?

A

Very common to get a dens-in-dente in these teeth (tooth within a tooth).

A dense-in-dente forms a pathway to the pulp which allows the tooth to lose vitality due to infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the radiographic features of a residual cyst?

A

Essentially a radicular cyst that has persisted following XLA of the associated tooth.

Well-defined, uni-locular, corticated radiolucency, located where there is a missing tooth (any denture bearing area, underneath a bridge etc.)

There may also be some loss of cortication if the cyst is infected.

Occurs where the cyst has not been enucleated / the socket hasn’t been cleaned out or undergone curettage, as a result the epithelium lining of the cyst remains. This can seal back off and start to produce fluid again, continuing to grow as a residual cyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the radiographic features of a dentigerous cyst?

A

Well defined, corticated, unilocular radiolucency (>4mm) associated with the crown of an unerupted, often displaced tooth.

Radiolucency tends to stop at the ACJ encompassing the entirety of the crown. But if it’s more extensive, it can encompass more of the tooth or even be displaced to one side of the crown.

Associated tooth, adjacent teeth may be displaced.

Damage to the adjacent teeth (resorption, although this is not very common)

Displacement of adjacent structures (antrum floor, ID canal)

Buccal expansion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Most common site for a dentigerous cyst to form includes:

A

Lower 8s
Lower premolars

Upper 3s
Upper 8s?
Upper premolars

Supernumeraries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What issue may arise when trying to diagnose a dentigerous cyst?

A

A dentigerous cyst occurs as a result of fluid accumulation between the enamel follicle and the enamel.

Radiographically, the cyst therefore presents as an expansion of the follicular space.

Up to 4mm from the crown to the edge of the follicle is considered a normal follicular space. If it is greater than this, we should consider cystic degeneration of the follicle

But when a tooth is close to eruption, there may be some natural widening of the follicular space. This is just a physiological response to age and eruption. As a result, the follicle may be a little more prominent just before a tooth erupts.

Up to 4mm from the crown to the edge of the follicle (ACJ) is considered a normal follicular space. If it is greater than this, we would consider cystic degeneration of the follicle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describe the radiographic features of an odontogenic keratocyst

A

Well defined, corticated, multilocular radiolucency, often with a scalloped margin

Can be pseudolocular (lobulated outline with the impression of multiple locules or separate areas within the cyst but no bony septa dividing the cavity) instead of multilocular (separate cysts adjacent to each other (cyst within cysts))

Can appear in a dentigerous relation (e.g. peri-coronal radiolucency around an unerupted tooth, particularly around a L8, can mimic a dentigerous cyst therefore)

Commonly located in the angle of the mandible/posterior body of the mandible. Can be seen in the maxilla (most commonly anteriorly, where the canines are)

Can displace associated teeth or structures (ID canal)

Can damage adjacent teeth (external root resorption)

These cysts tend to take the path of least resistance when growing. As a result, they tend to grow quite long or quite lengthy through the mandible e.g., through the ramus all the way to body of the mandible, without any or very little expansion

Can be an incidental finding, very clinical few symptoms despite a very large lesion being present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Why do odontogenic keratocysts have a high recurrence rate?

A

If these lesions are large or multilocular, there’s a high chance of recurrence.

There are 2 reasons for this-

The epithelial cyst lining for keratocysts is very thin and friable. Some cysts like radicular cysts have quite a tough lining that can be removed quite easily but keratocysts have a more friable lining which sheds much more easily and therefore it is possible to leave cells of the lining behind. These can persist and grow to form another cyst

The chances of leaving behind cystic material also increases if it’s a lesion is multilocular with daughter cysts around the edge. Need to remove all the smaller locules within a cyst, otherwise the largest cavities can be cleared out leaving smaller daughter cysts behind, to persist and grow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Why is follow-up imaging indicated following the treatment of odontogenic keratocysts. What technique is used to take follow up images for these lesions?

A

Due to recurrence rate being high for these lesions.

The technique used to image the lesions will depend on lesion location e.g., a mandibular lesion will likely be followed up using a sectional OPT whereas something in the upper maxilla may be much harder to view in a 2D plane and therefore a CBCT may be better to follow the lesion up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What syndrome is associated with odontogenic keratocysts? List some of its other features

A

Gorlin Goltz syndrome

Multiple basal cell naevi
Skeletal abnormalities (rib and spinal)
Facial bossing
Hypertelorism
Calcification of falx cerebri

24
Q

How could odontogenic keratocysts found in a patient with Gorlin Goltz syndrome differ from a patient who doesn’t suffer from the syndrome?

A

Multiple odontogenic keratocysts found in patients with the syndrome

Tend to be located in unusual and uncommon places compared (rather than the angle of the mandible, we will often see them in the maxilla or in the anterior mandible)

Occur in a younger age group

25
Q

Describe the radiographic features of a lateral periodontal cyst

A

Well defined, corticated, unilocular radiolucency

On rare occasions, may be multilocular (botryiod variant)

Located to the side of a vital tooth, taking a tear drop shaped appearance, between the ACJ and and the apex of a tooth

Often located adjacent to mandibular premolars or in the anterior maxilla

Usually less than 1cm in size

May cause displacement of adjacent teeth

26
Q

Describe the radiographic features of a nasopalatine duct cyst

A

Non-odontogenic hard tissue cyst

Well defined, round or occasionally heart shaped, unilocular radiolucency at the midline of the upper central incisors (occasionally off to one side but will mostly appear symmetrical)

May appear heart shaped due to superimposition of the anterior nasal spine

Can look like they are associated with the apices of the maxillary incisors but these teeth should be vital. Should see a lamina dura around the outside of these teeth, although with large lesions, the lamina dura can be resorbed.

27
Q

On an occlusal radiograph, the incisive foramen and the nasopalatine canal present as radiolucencies. How would we differentiate between a nasopalatine duct cyst and these normal anatomical radiolucencies on this type of radiograph ?

A

A normal nasopalatine canal will be up to 6mm in size. If the canal measures more than this, we would need to consider whether this is a cyst as opposed to normal anatomy.

28
Q

Describe the radiographic features of a solitary bone cyst

A

Non-epithelial lined cavity within the bone (on surgical exploration, will just be an empty space in bone)

Moderately well defined or poorly corticated, unilocular radiolucency

Most commonly found in the mandible, particularly anteriorly and premolar/molar region

Superior margin of the lesion will arch up between the teeth (margin superiorly between the roots of the teeth)

Minimal or no displacement of associated teeth, will rarely be resorbed

Minimal to no expansion of the jaw

Usually seen in younger age groups, mostly children

29
Q

How may tumours of the jaw be classified?

A

Tumours of the jaw can be classified into 2 forms-

Benign (potential to impair QoL but unlikely to kill the patient if left untreated)

Malignant (potential to impair QoL and life expectancy, patient will likely die if left untreated)

Benign tumours of the jaw can be further divided into-
Odontogenic (those arising from the tooth forming tissues)

Non-odontogenic

Malignant tumours of the jaw (cancer) can also be further divided into-
Primary (cancer originates from the jaw)

Secondary (cancer has metastasised from another site in the body to the jaw, the jaw is the secondary site)

30
Q

There are several benign tumours of the jaw, but only 2 are seen as ‘true’ radiolucencies on a radiograph. List these

A

Ameloblastoma

Odontogenic myxoma

31
Q

List the benign odontogenic tumours of the jaw that present as initial radiolucencies but become more radiopaque as they mature (through calcification)

A

Calcifying epithelial odontogenic tumour

Ameloblastic fibroma

Ameloblastic fibro-odontoma

Adenomatoid odontogenic tumour

32
Q

List the benign non-odontogenic tumours of the jaw that present as initial radiolucencies but become more radiopaque as they mature (through calcification)

A

Intra-osseous haemangioma

33
Q

Describe the features of an ameloblastoma

A

Benign odontogenic tumour (most common odontogenic tumour but generally rare)

Locally invasive/aggressive, expansile but non-metastasising tumour

Mandible > maxilla, posterior aspect > anterior aspect

Radiographically presents as a well defined, corticated multilocular radiolucency, a soap bubble appearance with scalloped margins, damage to adjacent teeth (root resorption) and bony expansion. Can also displace teeth and adjacent vital structures such as the ID canal

One sub-type will present as a unilocular radiolucency (unicystic ameloblastoma)

34
Q

Describe the features of an odontogenic myxoma

A

Rare odontogenic tumour

Affects young adults

Radiographically presents as a multilocular lesion with the bony septa arranged at right angles to one another (like strings of a tennis racket)

Expansile

Can displace teeth

35
Q

Describe the features of a haemangioma

A

Very rare, non-odontogenic tumour

Vascular tumour in the bone marrow space

Can present at any age, but most commonly seen in adolescents

Very variable appearance but most commonly observe a multilocular, expansile lesion with a soap bubble/honey comb appearance. Can be poorly defined, almost blending into the adjacent bone

Displacement and resorption of associated teeth

36
Q

What is an intrinsic primary malignant bone tumour? Give an example

A

Tumours that arise from within the bone itself e.g., osteosarcoma

37
Q

What is an extrinsic primary tumour involving bone

A

Primary tumours which involve bone by being in close proximity or relation to it e.g., SCC on the oral mucosa has a close association to the underlying bone so as the tumour grows, it can involve the bone by infiltrating and eroding it

38
Q

What is a secondary tumour of the bone? Give an example

A

Metastatic tumour deposit within the bone from a primary tumour elsewhere in the body

39
Q

List some malignant tumours that can affect the jaw

A

Intrinsic primary malignant bone tumours (arise within the bone) e.g., osteosarcoma

Extrinsic primary tumour involving the bone e.g., SCC of the oral cavity

Secondary tumours

Lymphoreticular tumours of the bone e.g., multiple myeloma

40
Q

Describe the features of an osteosarcoma

A

Rare, primary intrinsic bone malignancy

Rapidly destructive

Radiographically, has a variable appearance. Can be osteolytic (appearing as an ill-defined ragged radiolucent area). Or can be osteosclerotic (appearing more radiopaque). Or can be mixed lytic/sclerotic (mixture of radiopacity and radiolucency)

Affected bone around the teeth will be destroyed, leading to looseness of associated teeth

41
Q

Describe the features of an extrinsic primary tumour involving bone

A

Most common extrinsic primary tumour involving bone that is seen in the oral cavity is SCC

Usually affects adults >50 years

Mandible more commonly affected than the maxilla

Once bone is involved, the radiographic appearance ranges from a radiolucency with slight erosion of the alveolar crest to a radiolucency with gross destruction and resorption of the bone. Bone destruction will be irregular and the radiolucency will have a non-corticated, irregular border. May be ill-defined in some regions

42
Q

Describe the features of a secondary (metastatic) bone tumour

A

Malignant tumour of the jaw bone that can arise from the following primary tumours/carcinomas-
Breast
Bronchus
Kidney
Prostate
Thyroid

Can present as an irregular, non-corticated radiolucency (caused by irregular bone destruction)

Tumour can arise along the the ID canal (leading to erosion of its borders) and mental foramen region

Unable to distinguish if the tumour seen is a primary or a secondary tumour (only biopsy can provide the answer)

Breast and prostate malignancies can result in osteogenic metastases in the jaw bone which will appear more radiopaque as opposed to radiolucent

43
Q

Describe the features of a lymphoreticular tumour of the bone

A

Multiple myeloma

Multifocal proliferation of plasma cells in the bone marrow

Can cause pain in the jaws

Affects middle aged adults most commonly

Radiographically presents as multiple, round, unilocular, well defined but non-corticated (punched out) lesions.

Difficult to see, unlikely to be able to diagnose multiple myeloma from dental imaging alone

44
Q

Describe the features of Langerhans cell disease

A

Tumour-like lesions in the bone, form due to proliferation of Langerhans cells and eosinophilic leucocytes

May be solitary or multifocal (throughout the skeleton)

A single deposit is known as a Solitary Eosinophilic Granuloma

Radiographically presents as round, unilocular, well defined but non-corticated (punched out) lesions.

Can get lesions involving the alveolus, in which case the bone around the teeth is destroyed, resulting in an appearance of floating teeth

45
Q

List some giant cell lesions

A

Central giant cell granuloma

Hyperparathyroidism

Cherubism

Aneurysmal bone cyst

46
Q

Describe the features of giant cell granuloma

A

Benign proliferation of fibrous tissue, often affecting the anterior mandible

Uncommon

Radiographically presents as a unilocular or multilocular radiolucency with smooth, well defined and corticated margins

Expansile

Can displace teeth

47
Q

Describe the features of hyperparathyroidism

A

Condition characterised by elevated parathyroid hormone (PTH)

Can be primary (parathyroid adenoma or hyperplasia)

OR secondary (kidney disease)

Will see a generalised decrease in bone density (osteopenia). Radiographically presents as a very fine trabecular pattern with a ‘ground glass’ appearance and loss of lamina dura in associated teeth

48
Q

Describe the features of a Brown tumour

A

Condition caused by elevated parathyroid hormone (PTH)

Cause patients to develop radiolucent lesions in the jaw due to decreased bone density (osteopenia)

Indistinguishable from central giant cell lesions (as they have the same radiographic appearance which may be radiolucent, multilocular or unilocular and quite expansile)

If a patient presents with a giant cell lesion, always consider undiagnosed hyperparathyroidism / Brown tumour with a referral for biopsy and histopathological examination

49
Q

Describe the features of cherubism

A

Rare genetic condition affecting children

Autosomal dominant

Males more commonly affected than females

Onset 2-4 years

Radiographically presents as bilateral multilocular radiolucencies in the angle of the mandible +/- maxilla.

Expansile lesions

These radiolucencies will resemble other giant cell lesions

Require no treatment as the features will resolve on their own as the child reaches puberty

50
Q

Describe the features of an aneurysmal bone cyst

A

Non-epithelialised cyst

Expansile, osteolytic lesion

Rare in jaws, mostly affects the long bones

Commonly seen in adolescence and young adulthood

Radiographically presents as a radiolucency with smooth corticated peripheries and faint trabeculation (resulting in a soap bubble appearance)

Very expansile (balloon-like expansion)

Can cause displacement of teeth

51
Q

Some conditions can affect the entire length of the jaw bone (widespread radiolucency rather than a single discrete radiolucent lesion). List these

A

Osteoporosis

Sickle cell anaemia

Thalassaemia

52
Q

Describe the features of osteoporosis

A

Generalised decrease in bone mass.

Can be primary or secondary-

Primary osteoporosis occurs with the ageing process of bone (variation of normal bone)

Secondary osteoporosis may result from nutritional deficiency, hormonal imbalance or be related to corticosteroid use

Causes the thinning of the cortices (lower and upper borders of the jaw) and the lamina dura. This makes the bone more brittle and weaker. The resulting effect is an increased risk of fracture in osteoporotic bones

53
Q

What is sickle cell anaemia

A

Hereditary chronic haemolytic blood disorder

54
Q

Describe the effects of sickle cell anaemia on bone

A

Thickening of frontal and parietal bones

Generalised osteoporosis (which will result in thinning of the cortices of the mandible and a more radiolucent appearance of the bone)

Coarse trabeculation, horizontally aligned trabecular pattern (little horizontal lines that resemble a step ladder)

Maxilla may become enlarged (can be seen clinically or radiographically)

Usually, teeth will remain unaffected, with normal lamina dura

55
Q

What is thalassaemia?

A

Chronic haemolytic anaemia

56
Q

Describe the effects of Thalassaemia on bone

A

Thinning of cortical structures

Coarse trabeculation with very large marrow spaces

Expansion with obliteration of the maxillary antra (won’t see a normal antral floor)

Spike-shaped/shortened roots of teeth