Radiology - recognising common pathologies of the female genital tract Flashcards
A
Infundibulum
B
fundus
C
Fallopian tube
D
Fimbrae
E
Broad ligament of ovary
F
endometrium
g
Myometrium
h
vagina
i
Cervix
j
Body of uterus
k
Ovary
l
Vaginal vault
Why is important to have a full bladder for a trans abdominal ultrasound scan of the uterus?
The US waves can easily pass through fluid resulting in an ‘acoustic window’ allowing for a clearer image of the uterus and ovaries etc.
What colour is the endometrial stipe on an ultrasound scan?
White/brighter- it is hyper echoic in relation to fat
What colour is the endometrium in an ultrasound scan?
It is darker, it is hypo echoic in comparison to fat
What are the pros of a transvaginal ultrasound?
- Better image of the uterus overall
* Doesn’t require a full bladder
What are the cons of a transvaginal ultrasound?
- harder to see the ovaries
* More invasive
What are the cons of MRI for imaging of the female genital tract?
- No metal - large magnet
- Problem for those with claustrophobia
- Loud
- Takes a long time
- Not so readily available
What are the pros of MRI for imaging of the female genital tract?
- Good for soft tissue detail
* Best resolution out of imaging options and good for pathology
Explain the different colours on an MRI scan of the female genital tract with T2 sequence
- Bright means fluid
- Endometrial bright
- Junctional zone dark
- Myometrium in the middle
Label
a- junctional zone b- internal os c- endocervix d- external os e- cervical stroma f- myometrium g- endometrium
What are the pros of using CT for imaging of the female genital tract?
- Quick
* Good for seeing any metastases
What are the cons of using CT for imaging of the female genital tract?
- Irradiating
* not the best for resolution but can use IV contrast
Benign ovarian pathologies
- Ovarian follicles
- Dermoid cysts
- Haemorrhagic cysts
- Endometriomas
- Polycystic ovarian syndrome
- Ovarian torsion
Why may the ovaries not be seen on ultrasound?
- Bowel in the way
- Fat
- if post menopausal they shrink
Ovarian follicles
- Common
- benign
- asymptomatic
- Most don’t need follow up unless greater than 5cm in premenopausal or up to 3cm in post menopausal women
Haemorrhagic cyst
- Haemorrhage into a dominant follicle/funcitonal cyst
- Asymptomatic or might present with pain
- Follow up in 6 weeks- likely to disappear
Describe haemorrhage cyst on ultrasound
- Cyst with haemorrhage debris
- Dark circle with white flecks throughout
- If you put on the doppler will light up around the outside of the cyst but not inside
Dermoid cyst
- Often found incidentally in young women
- Common benign neoplasm
- Contain elements from multiple germ cell layers
Dermoid cyst on x ray
- Bright
* Calcification due to presence of bone/teeth
Describe a dermoid cyst on ultrasound
Heterogenous mass, solid nodule
Describe dermoid cyst on CT
The presence of fat/fluid/calcification/soft tissue almost fully confirms
What is polycystic ovarian syndrome?
- Chronic anovulation associated with excess of androgen
- Clinical and/or biochemical hyperandrogenism
- Multiple immature follicles due to development being stopped
Describe polycystic ovaries on ultrasound
Lots of small dark circles in ovary
What is ovarian torsion?
Ovary twists on its vascular pedicle
Who is mainly affected by ovarian torsion?
Young women
What do patients with ovarian torsion present with?
- Abdomen/pelvic pain
* Nausea and vomiting
What is an ovarian torsion associated with?
1/2 of the time associated with an ovarian mass e.g. a dermoid cyst
Describe ovarian torsion on ultrasound
- Enlarged ovary
- Free fluid in the pelvis
- Ovary may show absent vascularity (if using doppler) (may be ischaemia of the ovary due to reduced vascularity)
What are the signs and symptoms of ovarian cancer?
- Abdominal distension
- Pelvic or abdominal pain
- Feeling full and loss of appetite
- increasing urinary urgency or frequency
- irritable bowel syndrome > 50
Describe the risk of malignancy index
•RMI = ultrasound score x menopausal score x CA125 •Menopausal score: - premenopausal = 1 - postmenopausal = 3 •Ultrasound score: - 0 =none - 1 = one abnormality - 3 = two or more abnormalities
What RMI score is concerning for malignancy?
RMI of >200
What are the features of malignancy on ultrasound?
- Irregualr solid or multi-lobulated cystic mass
- Solid components on cyst wall
- Bilateral ovarian lesions
- Ascites, peritoneal nodules, or evidence of metastases
What are the types of ovarian carcinoma?
- Epithelial
* Non epithelial
What are the epithelial ovarian carcinomas
- Serous (80-85%)
- Mucinous (endocervical and intestinal phenotype)
- clear cell
- Endometroid
- brenners
- Squamous
What are the non-epithelial ovarian carcinomas?
•Germ cell: dysgerminoma, teratoma etc.
•Sex chord:
- granulosa cell
- sertoli leydig, thecoma, fibroma
Which cancers tend to metastasise to the ovaries?
- Uterus
- Colon
- Breast
- Lymphoma
- Stomach and pancreas can drop metastasise
Describe serous epithelial ovarian cancer
- Most are benign but 25% are malignant
* Look like a large cystic mass on imaging
what are the malignant features of serous epithelial cancer?
- Thick separations
- Solid components
- Ascites, peritoneal metastases, lymphadenopathy, distant metastases
What are the benign uterine pathologies?
- Fibroids
* Adenomyosis
What are fibroids
Most common solid benign uterine lesion
Describe the presentation of fibroids
- may cause pain, infertility or menorrhagia
* Usually found incidentally in post menopausal women
Describe fibroids on ultrasound imaging
•Features are variable
•Hypoechoic mass on ultrasound
•Often make the uterus look bulky/lobulated
What is andenomyosis?
When endometrial tissue has migrated into the myometrium
Describe the presentation of adenomyosis
•May be asymptomatic •May get: - dysmenorrhea - menorrhagia - dyspareunia (pain during intercourse) - chronic pelvic pain
Describe imaging of adenomyosis
thickening of the junctional zone with no uniform dark zone on MRI
What are the investigations for endometrial cancer?
- Initally a transvaginal US
- If endometrial thickening is greater than 5mm then MRI to look for local invasion
- CT to detect distant metastases
What is the most common presentation of endometrial cancer?
Post menopausal PV bleeding
What is cervical cancer mainly associated with?
HPV
Presentation of cervical cancer
- Vaginal bleeding
- Abnormal discharge (foul smelling, brown, watery or mixed with blood)
- Abnormal cervical cancer screening test
What is the parametrium?
A fibrous band that separates the cervix from the bladder
What is the significance of the parametrium in cervical cancer?
- Stage 2b and above if invasion
- If it is not invaded then surgery
- If it is invaded then chemotherapy or radiation
What is vaginal cancer often associated with?
Cervix cancer metastasis and HPV
Describe the presentation of vaginal cancer
Lump, itch or bleeding that won’t go away