radiation risk and patient dosimetry Flashcards
what are the units of absorbed dose
Gy
what are the units of equivalent dose
Sv
eqn linking absorbed dose to equivalent dose
H_T=D x w_R
what are stochastic effects
prob. proportional to dose, no thresh
stochastic effect of interest
carcinogenesis
why is there a reduced probability of bad effect after a certain dose
because of e.g. cell kill
what are deterministic effects
tissue reactions
only happen above a threshold where the severity becomes increased with dose
what does somatic effects mean
affect the irradiated individual
what are two somatic effects
carcinogenesis and deterministic effects
what radiation effect is there no convincing evidence for
chromosome damage
what is chromosome damage mechanism
breakage followed by faulty repair
what are some issues with a genetic risk assessment (3)
- only gonad exposure is relevant
- mutations may be recessive
- mutations may be unstable
problems estimating dose to an individual (2)
- different organs and tissues have different radiosensitivies
- doses to organs and tissues on uniformly distributed
define absorbed dose and give the units
absorbed dose (D) = energy absorbed per unit mass (Gy)
what does equivalent dose take into account
differing biological effects induced by the same absorbed dose from radiations with different LET
what does effective dose take into account
differing radiosensitivities of tissues and organs
what are the units of effective dose
sieverts