Radiation Biology Flashcards
Depress circulating lymphocytes
0.25 Gy
Bone Marrow Acute Radiation Syndrome (dose and latent period)
> 2 Gy
1-6 weeks
GI Acute Radiaition Syndrome (dose and latent period)
> 8 Gy
5-7 days
CNS Acute Radiation Syndrome (dose and latent period)
> 20-50 Gy
4-6 hours
Nausea 30% of time
1 Gy
LD 50/30 (without/with treatment)
3-4 Gy without
8.5 Gy with
LD 50/60 (for bone marrow failure)
3-4 Gy
LD 50/4 (GI failure)
10 Gy
Fetal - first 2 weeks
50-100 mGy for fetal loss (all or nothing)
Fetal - 8-15 weeks
> 100-200 mGy reduced head diameter and mental retardation
30 IQ point drop per 1 Sv
with 1 Sv 40% chance retardation
Fetal - >15 weeks
less sensitive
Fetal - 3-8 weeks
> 250 mSv growth retardation
Increased risk childhood cancer (after week 9)
10-20 mSv
Fetal thyroid vulnerable
week 9 onward
Adult and child cancer risk (BEIR 5 and UNSCEAR)
8%/Sv, but with reduction factor 4-5%/Sv (1/10 if older than 50)
Up to 15%/Sv for child
Early transient erythema (dose and onset)
2 Gy
hours
Severe, robust, erythema (dose and onset)
6 Gy
1 week
Telangiectasia (dose and onset)
10 Gy
52 weeks
Dry desquamation (dose and onset)
13 Gy
4 weeks
Moist desquamation/ulceration (dose and onset)
18 Gy
4 weeks
Secondary ulceration (dose and onset)
24 Gy
>6 weeks
Temporary epilation (dose and onset)
3 Gy
21 days
Permanent epilation (dose and onset)
7 Gy
21 days
Annual lens dose rate limit
150 mSv (might become 20 mSv)
Acute or chronic exposure for cataract
0.5 Gy (others say 2.5 Gy)
Male temporary sterility
0.15-2.5 Gy
Male permanent sterility
5 Gy
Female permanent sterility (age 12)
10 Gy
Female permanent sterility (age 45)
2 Gy
Female permanent sterility (no age)
6 Gy
Double natural/spontaneous mutation rate
1 Gy
Effective dose of US background radiation
3 mSv/year (55% radon)
Sentinel event dose
15 Gy to single field
Radiation worker dose limit
50 mSv/yr
Radiation worker extremity/organ dose limit
500 mSv/yr
Public exposure (infrequent)
5 mSv/yr
Public exposure (continuous)
1 mSv/yr
Fetus of worker for pregnancy
5 mSv
Fetus (post declared pregnancy)
0.5 mSv/month
Controlled areas - public exposure
50 mSv/yr
Uncontrolled areas - public exposure
5 mSv/yr
Genetically significant dose
0.25 mSv
Radiation Area Sign
0.005 rem/hr (0.05 mSv/hr) at 30 cm
Radioiodine limit for admission
7 mR/hr at 1 meter from chest
33 mCi of residual activity
High Radiation Area Sign
0.1 rem/hr (1 mSv/hr) at 30 cm
Very High Radiation Area Sign
500 rad/hr (5 gray/hr) at 1 meter
Receiving radioactive material wipe test
> 6600 dpm/300 cm2 not allowed
White 1 (surface and 1 meter)
< 0.5 mrem/hr surface
0 mrem/hr at 1 meter
Yellow 2 (surface and 1 meter)
< 50 mrem/hr surface
< 1 mrem/hr at 1 meter
Yellow 3 (surface and 1 meter)
< 200 mrem/hr surface
< 10 mrem at 1 meter
Nuclear restricted area
> 2mrem/hr or > 100 mrem/year
