RADBIO Flashcards

1
Q

When is the advent of the age of the atomic bomb happen?

A

1940s

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2
Q

It is a mathematical
relationship between various radiation dose levels and
magnitude of the observed response.

A

Radiation dose-response relationship

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3
Q

Radiation dose response relationship have two important applications in radiology. First, these experimentally determined relationships are used to
design therapeutic treatment routines for _____

A

patients with cancer

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4
Q

Radiobiologic studies also have been designed to yield information on
the ______.

A

effects of low-dose irradiation

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5
Q

These studies and the dose response relationships revealed provide the basis for radiation
management activities and are particularly significant for_____

A

diagnostic radiology

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6
Q

Human responses to radiation exposure fall into two types:

A

Deterministic or Stochastic

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7
Q

Responses usually follow high-dose radiation exposure and appear as an early response

A

deterministic

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8
Q

deterministic exhibit a _____; there is a dose
below which no response occurs.

A

dose threshold

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9
Q

answer true or false.As radiation dose increases, the
severity of the response increases.

A

true

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10
Q

_____- skin burns
represent a deterministic response.

A

Radiation-induced

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11
Q

Stochastic Responses are______.

A

cancer, leukemia, or genetic effects

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12
Q

Such responses
usually follow low radiation exposure and appear as a late radiation
response years later

A

stochastic

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13
Q

In stochastic there is_____ and as radiation
dose increases, the frequency of response in a population increases.

A

no dose threshold

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14
Q

What are the two characteristic radiation dose-response relationship?

A

linear or nonlinear / threshold or nonthreshold

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15
Q

Answer with true or false: These
characteristics can be described mathematically or graphically

A

True

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16
Q

Threshold dose-response
relationship

A

deterministic

17
Q

Non-threshold dose-response
relationship

A

stochastic

18
Q

Non-linear dose-response
relationship

A

deterministic

19
Q

Severity of response increases
with radiation dose

A

deterministic

20
Q

Linear dose-response
relationship

A

stochastic

21
Q

Incidence of response
increases with radiation dose

A

stochastic

22
Q

When the radiation dose is doubled, the
response to radiation likewise is __–

A

doubled

23
Q

Dose-response relationships A and B
intersect the dose axis at zero or below. These relationships are therefore the _____ type.

A

linear,
nonthreshold (LNT

24
Q

In a nonthreshold
dose-response relationship, any dose,
regardless of its size, is expected to produce
a response.. Answer with true or false

A

true

25
Q

At zero dose, relationship A
exhibits a measurable response,

A

RN

26
Q

The level RN, called the_____, indicates that even without radiation
exposure, that type of response, such as
cancer, occurs

A

natural response
level

27
Q

(Radiation-induced cancer, leukemia, and
genetic effects follow a -____,___-_

A

linear, nonthreshold
dose-response relationship.

28
Q

All other radiation dose-response relationships
are ____

A

nonlinear

29
Q

Skin effects resulting from high-dose
fluoroscopy follow a __-_

A

sigmoid-type dose response relationship.)

30
Q

It is very difficult to determine the degree of
response, even that of early effects, because the number of
experimental animals that can be used is usually ___

A

small

31
Q

The principal interest in diagnostic imaging is
to estimate response at very low radiation
doses. Because this cannot be done directly,
we -___- the dose-response
relationship from the high-dose, known
region into the low-dose, unknown region

A

extrapolate

32
Q

This extrapolation invariably results in a
____-

A

linear, non-threshold dose-response
relationship

33
Q

the natural incidence may be higher
and there may be a ___

A

dose threshold.

34
Q

At very ____ irradiated subjects
experience less response than control
participants.

A

low doses

35
Q

Many radiation scientists today believe that the doseresponse relationship associated with medical radiation
falls in between the____

A

LNT and hormesis

36
Q

Regardless of our
concern for low radiation doses to large populations,
patient radiation dose___–
are totally acceptable considering the benefit to the
patient

A

less than approximately 50 mSv