Rabies

Question 1

How is the rabies vaccine administered?

Answer 1

IM in the deltoid area in doses of 1 mL according to the recommended schedules for pre- and post- exposure prophylaxis

vaccine should NEVER be adminsitered in the gluteal area because this results in in lower antibody titers

Question 2

Rabies

Answer 2

a rapidly progressive CNS infection caused by a ribonucleic acid (RNA) rhabdovirus affecting mammals, including humans

transmission via dogs, raccoons, skunks, bats, fox, coyote

incubation period can be up to 3 months

generally considerd to be 100% fatal once sx develop

most cases in developing countries

Question 3

Clinical Manifestation of Rabies infection

Answer 3

hydrophobia (inability to swallow water) – classic***

pharyngeal spasms

aerophobia (fear of drafts of fresh air)

hyperactivity

Question 4

Diagnosis of Rabies

Answer 4

Negri bodies (esoinophilic inclusion bodies in the cytoplasm of hippocampal nerve cells) are considered pathognomic and are found in the brain of dead animals

animals are observed 7 - 10 days to see if sx develop – if not they’re released or given back to owner