RA/OA Flashcards
1
Q
RA
A
Treat with NSAIDS and glucosteroids
Symmetric
DMARDS
TNF-alpha and IL-1
2
Q
NSAIDS
A
Eat something
Over the counter not prescription
Acetaminophen not for pain relief
GI irritation, stomach ulcer
3
Q
Glucocorticoids
A
Great for short term Long term - side effects Immunodeficiency Hyperglycemia Skin breakdown OP Weight gain odd Adrenal insufficiency Glaucoma Cataracts Classified based on potency (matters for adverse rxn) Taper off 50% each time
4
Q
DMARDS
A
Try to correct disease state Prevent further progression and destruction of joints 1st line Routine eye exam for retinal detachment Keep under 6 mg I Adverse Rxn N/V/D, alopecia, hard on liver Contraindicated in pregnant
5
Q
Imuran
A
DMARDS Organ tissue rejection Dosing is wt based N/V 12% occurrence White count low
6
Q
MTX
A
One of most common DMARDS
1st used in peds and adults
Drug rxn:
GI, alopecia, liver
7
Q
TNF-alpha inhibitor
A
2nd gen agent
Remicade- need hospital, also for Crohns, takes 2-3 hr for infusion
Increased risk of pulm infection
8
Q
OA
A
Treat with NSAIDs
Acetaminophen not effective
DMOADs new treatment
