RA 9288 Flashcards
Newborn Screening Act of 2004
RA 9288
When is the date of approval?
April 7, 2004
Who is the President who signed the Republic Act?
Gloria Macapagal-Arroyo
Declaration of Policy:
- promote and protect the right to health of the people
- institutionalize a national newborn screening program
- collaborate with government and non-government agencies
National newborn screening program should be:
Comprehensive
Integrative
Sustainable
Objectives of NBS:
- ensure that every newborn has access to newborn screening
- establish and integrate a newborn screening system
- ensure that all health practitioners are aware of the advantages of NBS
- ensure that parents recognize their responsibilities in promoting their child’s right to health
Comprehensive National Newborn screening system
- education of relevant stakeholders
- collection and biochemical screening of blood samples
- tracking and confirmatory testing
- clinical evaluation and medical confirmation
- medical management
- evaluation activities
Follow-up
Monitoring a newborn with heritable condition
Recall
Procedure for locating a newborn with possible heritable condition
Treatment
provision of medicine, surgical management, and dietary prescription for newborns
Health institutions
hospitals, infirmaries, lying-in centers, health centers, puericulture centers
Health practitioners
physicians, nurses, midwives, nursing aides, traditional birth attendants, medical technologists
Parent education
Provision of information on NBS
Newborn
A child from the time of delivery up to 30 days old
Heritable conditions
any condition that can result to mental retardation, physical deformity, or death if left untreated and undetected (usually inherited from the genes of parents)
Phenylketonuria (PKU)
Accumulation of phenylalanine
Absence of phenylalanine hydroxylase
Toxic and causes brain problems such as mental retardation and microcephaly
High phenylalanine
Urine odor of phenylketonuria
Mousy
Diet of babies with phenylketonuria
No phenylalanine-rich food in their diet
- meat products
- seafood
- dairy products
Maple Syrup Urine disease
Accumulation of leucine, isoleucine, valine
Absence or reduced branched chain alpha-ketoacid dehydrogenase
Babies are normal at birth but exhibits:
lethargy
vomiting
lack of appetite
failure to thrive
MSUD urine odor…
Maple syrup or burnt sugar
Congenital Adrenal Hyperplasia
21 -hydroxylase deficiency
decreased cortisol and aldosterone production, increased androgens
increased adrenocorticotropic hormone (ACTH)
Where are androgens produced?
Zona reticularis
Where is cortisol produced?
Zona fasciculata
Functions of cortisol
Stress hormone, promotes gluconeogenesis
Where is aldosterone produced?
Zona glomerulosa
Aldosterone is for…
Electrolyte imbalance
Excretes K, retains Na
Increases blood pressure and volume
