Quizzes and Terms Flashcards
Protease that degrade debris formed during the inflammatory phase of wound healing
MMP’s
Describe the sequence of the preoperative phase of healing
- angiogenesis
- granulation tissue formation
- wound contraction
- epithelialization
Wound contraction is accomplished by?
myofibroblasts
Myofibroblasts stem from?
fibroblasts
Which layers of the integument are vascularized?
dermis and hypodermis
Langerhans’s cells are contained in what layer of the integument?
Epidermis
The function of the Langerhans’s cells is to do what?
protect against infection
Which cells are found in the epidermis?
- keratinocytes
- merkel cells
- melanocytes
- Langerhans’ cells
During diapedesis these cells migrate through the capillar walls
PMN’s
What stage does diapedesis occur?
hemostasis/inflammatory
What are the 3 stages of wound healing and the typical time frame.
hemostasis/inflammatory: 0-4 days
proliferative: 4-21 days
maturation/remodeling: up to 2 years
What is a function of the hypodermis
insulation
T of F, the dermis regulates fluid loss?
False.
Name the layers of the integument
- epidermis
- dermis
- subcuteaneous tissue
- deeper tissue
Name the layers of the epidermis
- stratum corneum
- stratum lucidum
- stratum granulosum
- stratum spinosum
- stratum germanotivum or basale
Name the layers of the dermis
- papillary dermis
2. reticular dermis
Name the cells in the dermis
- fibroblasts
- macrophages and WBC
- mast cells
- receptors
A wound that has loss of superficial epidermis only is called what?
erosion wound
A wound that has loss of epidermis and part of the dermis is called what?
partial thickness wound
A wound that has loss of epidermis, dermis and extends to the subcutaneous layer is called what?
full thickness wound
what are the phases of healing?
- hemostasis/inflammation
- proliferation
- remodeling
Name 3 chemical mediators in the inflammation phase of healing.
- cytokines
- chemotactic agents
- growth factors.
which type of debridement is not consisdred selective? sharp autolytic enzymatic mechanical
mechanical
arrange the following terms in order of increasing bioburden
colonization
contamination
infection
contamination > colonization > infection
a patient has fungus infection in the wound. which of the following would you NOT put in the wound bed Gentamycin Miconazole Nystatin Oxiconazonle
Gentamycin - it is an antiobiotic
the use of endogenous enzymes to digest necrosis followed by the application of moisture retentive dressing can be classified as what type of debridement?
autolytic debridement
Serial instrument debridement is a type sharp debridement, which tools would you use and why?
forceps and scissors to remove loosely adherent necrotic tissue. this is maintenance debridement done over several visits with minimal pain and bleeding. some prior tissue prep may be needed.
3 factors to consider during nutritional assessment of a patient with a wound
etiology, comorbidities, BMI
NOT INR!
Albumin is not an accurate marker to determine malnutrition because
it has a long half life of 20 days
you are treating an obese pt with L BKA. she has a wound on her residual limb and cannot wear her prosthesis as a result. the wound is infected wiht MRSA.the appropriate team member to converse with regarding dressing selection is ?
WOCN and infectious disease MD
Protein levels are vital for homeostasis. Patients with copious amounts of drainage/exudate are at risk for which of the following issues?
negative nitrogen balance
3 signs of infection
- sudden change in pain level
- decline in wound bed status
- periwound erythema that is disproportional to the size of the wond
a patient with irradiated skin should be instructed
do not:
wear constrictive clothing or jewelry
scratch skin if it itches
use hot tubs, saunas, or take long hot showers
use adhesive bandages
DO: apply sunscreen to areas where direct sun exposure is anticipated